Warp Drive Bio is driving the reemergence of natural products in the era of genomics to create breakthrough treatments that make an important difference in the lives of patients. Built upon the belief that nature is the world’s most powerful medicinal chemist, Warp Drive Bio is deploying a battery of state-of-the-art technologies to access powerful drugs that are now hidden within microbes.

At Warp Drive Bio, we are building a proprietary “genomic search engine,” where the search query line consists of DNA sequences that encode the chemomeme within biosynthetic gene clusters, and the search space is defined by the universe of all accessible bacterial genomes. We are focusing this innovative search engine on chemomemes having high pharmaceutical pedigree, novel and profound biological effects that tap into areas of high unmet medical need, and the ability to access targets that abiotic small molecules and monoclonal antibodies cannot.

Job Description:

We are seeking a talented and motivated scientist with a diverse skill set in cellular and molecular biology, drug discovery, and biochemistry. The successful candidate will be responsible for identifying the mechanism of action of compounds shown to have biological activity via screening and target validation.

Primary responsibilities will include:

• Working with  a multi-disciplinary team of scientists to identify and validate therapeutic targets
• Developing and performing RNAi, cell based and biochemical assays to identify mechanisms of action
• Identifying and leveraging experts in academia for productive collaboration, as well contract research organizations for compound evaluation using in vitro systems and in vivo models
• Troubleshooting experiments and analyzing data generated internally and by collaborators

Minimum Requirements:

• PhD in Molecular or Cellular Biology, Biochemistry or related discipline
• 5-10 years relevant industry experience
• Expertise in cell and biochemical assay development to determine mechanism of action
• Experience with target validation and in vivo mechanism of action studies with a broad range of bioactive small molecules
• A broad scientific background with strong ability to evaluate compounds and targets across varying applications in broad disease areas (e.g.-infectious diseases, inflammation, cancer biology, autoimmunity) is essential.
• Ability to think creatively and broadly about applications of natural products compounds for diseases ranging from antibiotics to anti-cancer therapeutics
• Proven track record of establishing collaborations with academic labs
• Experience working in multi-disciplinary teams of scientists in a fast-paced, multi-disciplinary environment to accomplish project and company goals
• Experience with project leadership and setting milestones, as well as experience holding self and others accountable.
• Excellent verbal and written communications skills

To be considered for this role, please submit your resume to careers@warpdrivebio.com

Note to Employment Agencies: Please do not forward any agency resumes. Warp Drive Bio is not responsible for any fees related to resumes that are unsolicited.

Warp Drive Bio will only accept job applications from candidates who are properly documented with authorization to work in the United States.

Warp Drive Bio is driving the reemergence of natural products in the era of genomics to create breakthrough treatments that make an important difference in the lives of patients. Built upon the belief that nature is the world’s most powerful medicinal chemist, Warp Drive Bio is deploying a battery of state-of-the-art technologies to access powerful drugs that are now hidden within microbes.

At Warp Drive Bio, we are building a proprietary “genomic search engine,” where the search query line consists of DNA sequences that encode the chemomeme within biosynthetic gene clusters, and the search space is defined by the universe of all accessible bacterial genomes. We are focusing this innovative search engine on chemomemes having high pharmaceutical pedigree, novel and profound biological effects that tap into areas of high unmet medical need, and the ability to access targets that abiotic small molecules and monoclonal antibodies cannot.

Job Description:

We are seeking a PhD scientist with a deep knowledge of molecular biology techniques to be a key contributor in the Molecular Biology team.   In this role, you will work with libraries from diverse organisms and should be familiar with a variety of techniques to be able to perform genetic engineering in fastidious organisms, as well as be able to solve technical issues related to sub-cloning and expression across species.

The successful applicant have broad and deep expertise in genetic manipulation of yeast, E. coli and streptomycetes.  The successful candidate will have demonstrable experience managing projects and planning workflows with multi-disciplinary teams. You will be highly motivated, an excellent communicator who is able to manage changing priorities in a fast-paced, entrepreneurial, start-up environment.

Minimum Requirements:

• PhD in molecular biology, genetics, biochemistry or other relevant scientific field with 3-7 years relevant experience 
• Proven expertise in cloning biosynthetic gene clusters, site-directed mutagenesis and working with engineered overexpression systems
• Experience with standard molecular biology techniques (e.g. subcloning, mutagenesis, library construction, transfection, primer design, and DNA/protein sequence analysis), automatic liquid handling, and technology development
• Experience working with actinomyces/ streptomycetes needed
• Candidates with broad knowledge of bacterial and fungal molecular and cell biology techniques strongly preferred
• Familiarity with protein expression using E. coli, baculovirus systems and mammalian cells
• Significant experience in interpretation of DNA sequencing data, gene expression analysis, and molecular evolution analysis
• Knowledge of computing software for DNA analysis, as well as working knowledge in bioinformatics and statistical methods
• Knowledge of databases for project management / data tracking.
• Proven rigor in experimental design, optimization, data interpretation, and analysis 
• Demonstrated experience of successful planning and management of multiple projects / workflows.
• Demonstrated record of creative and innovative thinking 
• Demonstrated ability to work independently, as well as part of a team 
• Good interpersonal and communication skills, both written and verbal

To be considered for this role, please submit your resume to careers@warpdrivebio.com

Note to Employment Agencies: Please do not forward any agency resumes. Warp Drive Bio is not responsible for any fees related to resumes that are unsolicited.

Warp Drive Bio will only accept job applications from candidates who are properly documented with authorization to work in the United States.

Responsibilities:

To ensure the QC, publishing and technical quality of scientific documents, ensuring compliance with internal and external guidelines and supporting the timely compilation of submissions to HAs

Compile, integrate and publish nonclinical documents with state-of-the-art word processing, electronic publishing and document management systems in the company's development environment

Perform technical quality control (electronic functionality, adherence to internal and external document standards) of nonclinical and clinical documents

Conduct document issue resolution with customers and collaborators

Requirements:

At least 1-3 years' experience with electronic document management systems, publishing tools

Basic knowledge of document publishing / document management including CoreDossier, Adobe Acrobat, ISI toolbox and / ISI publisher

Basic knowledge of GxPs and OECD regulations

Basic experience in non-clinical and/or clinical report preparation and submission

Education:

Undergraduate degree, preferably in scientific field or related experience

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com
 
Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors.
Our clients value the basic integrity, customer service and industry expertise that defines our organization.
 
Commonwealth Sciences, Inc.
www.cwsciences.com

Looking for an individual to publish and QC scientific documentation including study reports for submission to regulatory authorities

Requirements:

• 1-3 years experience with electronic document management systems, publishing tools
• Basic knowledge of document publishing / document management including CoreDossier, Adobe Acrobat, ISI toolbox and / ISI publisher
• Basic experience in non-clinical and/or clinical report preparation and submission.
• Basic knowledge of regulatory requirements and pharmaceutical development
• Basic knowledge and compliance with the Good Laboratory Practices and Standard Operating Procedures

Education:

AS/BS in the life sciences

Candidates must live local and be a US Citizen or Green Card Holder
 
Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry
professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience.
CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors.
Our clients value the basic integrity, customer service and industry expertise that defines our organization.
 
Commonwealth Sciences, Inc.
 
www.cwsciences.com
 

Looking for an individual to be a key contributor in the Sample Management Group.  The successful candidate will be primarily responsible for processing new compounds and inventory requests.
 
Requirements:
 
Primary responsibility will be the handling of all new compound orders
Weighing solids in order to create solutions via Tecan liquid handler.
Should have a thorough knowledge of activities related to compound management.
Experience working with laboratory robotics
Ability to diagnose and triage hardware and software issues quickly
Experience with Tecan Genesis, Biomicrolab Volume Checker, Biomicrolab Tube Sorter is a plus

Education: AS/BS in life sciences
 
 
Candidates must live local and be a US Citizen or Green Card Holder
 
Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry
professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience.
CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors.
Our clients value the basic integrity, customer service and industry expertise that defines our organization.
 
Commonwealth Sciences, Inc.
 
www.cwsciences.com
 

Responsibilities

Performing analytical chemistry assays based on new and existing methodologies.
Operating analytical instrumentation such as HPLC, GC, GC/MS, FTIR, Titrator, Particle Size Analyzer.
Developing, establishing, and validating analytical testing methodology used to control raw materials, production intermediates, and final products. Transferring documented analytical methods to the QC department.

Qualifications
BS in Chemistry degree required.
1+ years of experience in a laboratory setting working with analytical instrumentation like HPLC, GC, GC-MS, FTIR, UV-VIS equipment, and data stations required. Demonstrated computer literacy, including word processing, spreadsheets, structural drawings, and databases preferably in a Windows environment.

Candidates must live local and be a US Citizen or Green Card Holder
 
Email resume to: jobs@cwsciences.com
 
Commonwealth Sciences is a professional recruiting firm specializing in science, engineering and green technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise,advanced recruiting tools and years of staffing experience. CWS works with a
variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.
 
Commonwealth Sciences, Inc.
 
www.cwsciences.com

The Director, Nova Diabetes Care (NDC) is responsible for directing all business functions within the consumer glucose division in the United States. The Director of NDC has complete P&L responsibility for all consumer blood glucose activities within the domestic market. The Director will be responsible for all functions related to Sales, Sales Operations and Marketing with dotted line responsibility to Manufacturing and Customer Call Center.  Job Responsibilities include: development of sales forecast, budgets and compensation plans; leadership of National Account Managers, Director of Sales, sales teams and operation activities and presentation of business to senior leadership.  The Director will develop and drive strategic goals, engage in business development, interface with key accounts and negotiate sales contracts. This position will also have direct reports including Director of Sales, Sales Operations Manager and all National Account Managers (DME, Retail and Managed Care channels).

Requirements:  BS degree, at least 5-10 years of diabetes industry sales channels experience, proven ability to lead, manage, coach and mentor sales teams and create a strategic vision, strong financial, analytical and negotiation skills. Ideally position is based in Waltham, MA

 Nova Diabetes Care, LLC is an independent, wholly owned subsidiary of Nova Biomedical and is the exclusive distributor of Nova Max products in the United States.

Nova Biomedical develops, manufactures and sells advanced technology blood testing analyzers based on electrochemical and optical measuring techniques. We employ over 1,000 people, have sales and service subsidiaries in 7 countries and distributors in over 90 other countries. Nova has manufacturing facilities in Waltham and Billerica, Massachusetts, as well as Taipei, Taiwan.  Nova is one of the 25 largest in vitro diagnostic companies in the world and the largest privately owned in vitro diagnostic company in the United States.

www.novadiabetescare.com and www.novabiomedical.com

Description:  

Candidate will be responsible for developing mammalian cell culture based processes for manufacturing viral vaccine candidates.  Will work to establish new viral vaccine expression platforms, prepare technology development protocols and reports in support of process transfer and regulatory documents.  

Requirements: 

PhD with 0-3 years of experience or M.S. with 3+ years of experience or B.S. with 6+ years of experience in an upstream process development role.Experience with mammalian cell culture and bioreactor operations is a must Must have experience in application of DOEs and other statistical techniques.

Candidates must live local and be a US Citizen or Green Card Holder
 
Email resume to: jobs@cwsciences.com
 
Commonwealth Sciences is a professional recruiting firm specializing in science, engineering and green technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise,advanced recruiting tools and years of staffing experience. CWS works with
a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.
 
Commonwealth Sciences, Inc.
 
www.cwsciences.com

• Design, development and evaluation of candidate vaccine formulations against infectious diseases
• Formulations through physicochemical characterization

• BS/MS/PhD in Pharmaceutics, Pharmaceutical Chemistry, Chemical Engineering, with 0 – 2 years experience
• Expertise in Assay development to evaluate formulations (HPLC, particle size, agarose gel electrophoresis, in-vitro cell based assays
• Knowledge of polymer- and/or lipid-base gene delivery systems is a plus

**Multiple Openings

Candidates must live local and be a US Citizen or Green Card Holder

Commonwealth Sciences is a professional recruiting firm specializing in science, engineering and green technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

http://www.cwsciences.com

Looking for a candidate to assist the lab manager in supervising a small chemistry group.  Responsibilities will include training of technicians, troubleshooting issues that arise and keeping the team on track.

Requirements:

BS/MS Chemistry/Biochemistry with 5 years of lab experience

Supervisory experience is a must
 

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in science, engineering and green technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise,advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

Description:  

Candidate will join a Bioanalytical/Biophysical group and provide protein analytics support for sample analysis and short term projects.  

Requirements:  

BS/MS with 1+ years experience analyzing proteins and have knowledge of protein purification and protein/protein interaction Must have hands on experience with peptides and intact proteins, with knowledge of handling complex biological samples Experience with HPLC, Size Exclusion Chromatography, Gel electrophoresis, and ELISA is a must Experience with UV/Vis, FT-IR, and Biacore is a plus

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.
www.cwsciences.com

Qualified candidates will have experience in the design and development of scientific software, including both applications and analysis pipelines; the demonstrated ability to work collaboratively with users to understand and solve problems; comfort working independently in a fast-paced and rapidly evolving environment; adaptability and an aptitude for software and hardware troubleshooting, and experience with the technologies listed below:

Qualifications: 

• Web-based application development using Perl, JavaScript, HTML and CSS
• Relational databases, including database design and SQL
• Mac OS X or other Unix-like operating systems
• Experience with signal and image processing, data visualization and interactive graphics, iOS app development, and neuroscience experience are all desirable but not required.
• Qualified candidates will have a Bachelors Degree in Computer Science or related discipline with 3-5 years experience
• Experience in the life science industry a plus

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.
www.cwsciences.com

Major Accountabilities:

Execute experiments independently to establish Phase I/II/III microbial and/or cell culture based manufacturing processes.
In collaboration with Research and Senior Technology Development team members conduct activities to establish new viral vaccine expression platforms.
Perform activities in support of one or more of the following deliverables: GMP cell banks and virus seed stocks, or definition of bulk upstream manufacturing processes.
Prepare technology development study protocols and reports in support of process transfer and regulatory documents. Must be able to do this independently and develop reports on your own.
Present results to colleagues at internal department and project sub-team meetings.

Skills

At least 2 years experience (MS) or 4 years of experience (BS) prior knowledge of sterile techniques and handling of mammalian/microbial cells. Experience with mammalian cell culture, microbial culture and bioreactor operations is a strong plus.
Demonstrated laboratory skills in the cell culture arena including associated analytical methods is a strong plus.
Must have experience in application of Design of Experiments and other statistical techniques.
Must be a self-starter and able to work with minimal supervision.
Will be responsible for working independently and delivering results.
The qualified candidate must be able to effectively partner with a diverse team members from various functions, multiple countries and members at various levels in organization
 

Education Requirements:

M.S. with 2 years experience or B.S. with 4 years of experience in pharmaceutical, biotechnology or related life sciences industry.

 

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in science, engineering and green technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise,advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

The Application Engineer will work with the Therapeutics Discovery and Development (TDD) platform within the Broad Institute to provide informatics solutions and support for all aspects of hit and lead discovery. Systems include electronic lab notebooks, LIMS for managing laboratory robotics, liquid handlers and detection technologies, tools to design and assess compound collections and analogs, databases and data import tools, and data validation, analysis and decision support environments. Must be able to effectively communicate with biologists, medicinal chemists and software engineers to provide application training and support, to translate screening, chemistry and data analysis requirements into software deliverables, and to troubleshoot, document and collaborate to resolve software problems.

CHARACTERISTIC DUTIES
- Provide end user support and training to TDD scientists using vendor and internally-developed data capture and analysis applications. Create and deliver training and support materials.
- Collaborate with biologists, chemists, software engineers and IT to define and document informatics requirements for drug discovery informatics and data analysis systems.
- Investigate issues with deployed systems and work with users and software engineers to determine the cause, provide immediate workarounds, and design long term solutions.
- Asses unmet business needs for users, facilitate build versus buy decisions and participate on cross-functional teams to implement selected solutions.REQUIREMENTS
- Minimum B.S. in biology, chemistry or computer science with three to five years of relevant work experience.
- Experience with small-molecule screening and hit progression is required. Some experience working in pharmaceutical drug discovery or development is a plus.
- Experience with electronic lab notebooks, LIMS and data analysis applications is preferred(e.g.CambridgeSoft, GeneData, Pipeline Pilot, Spotfire, Seurat). Experience with chemical databases and drawing applications or compound inventory management is a strong plus.
- Basic knowledge of relational database structure and SQL is required.
- Excellent written and oral communication skills are required, with a strong focus on customer support.
- Must possess strong organizational skills and an affinity for problem solving.Broad will not offer visa sponsorship for this position.

To apply for this position, please CLICK HERE

The RNAi Platform is the home for functional genomics at the Broad Institute. With RNAi, ORF, and TALE technologies, we seek to understand what genes do in the cell and how malfunctions in gene activity lead to human disease. We work with a wide-variety of groups at the Broad, studying biological problems ranging from cancer to infectious disease to psychiatric disorders. In this position, the successful candidate will work closely with the Target Accelerator, which aims to understand what genes are particularly crucial for disease, and the Klarman Cell Observatory, which is building the fundamental ‘wiring diagram’ for how a cell functions.

One powerful way to understand what a gene does is to perturb it and then measure the resulting cellular phenotype. We perturb genes by knocking down their expression with RNAi, increasing their expression with ORFs, or editing their genomic context with TALEs. How the cellular state has changed can be determined by mRNA expression profiling, proteomic approaches, imaging analysis, and many other assays. Fundamentally, all these experiments begin with cultured cells and the perturbagen of choice. The successful candidate will work closely with scientists in the RNAi Platform, Target Accelerator, and Klarman Observatory to optimize conditions for perturbing a wide range of cells for multiple downstream applications.

- Under the supervision of scientists in the RNAi Platform, she/he will execute cell-based lentiviral RNAi/ORF screens in a high-throughput environment with automated liquid handling
- She/he will interact with other RNAi Platform staff members to coordinate screening activities in a BL2+ laboratory
- Under the guidance of his/her supervisor, he/she will develop and optimize high-throughput cell based screening protocols
- She/he will plan, schedule and coordinate detailed phases of screens
- She/he will identify and resolve technical problems
- She/he will attend regular team meetings for experimental planning and analysis and/or present the results.

KEY RESPONSIBILITIES / ESSENTIAL FUNCTIONS
- Mammalian Cell Culture
- High-Throughput Screening
- Independent Data Analysis
- Planning, Organizing, Analyzing with Supervisor
- Required: B.A., Biology or related
- no minimum requirement
- Experience with high-throughput, mammalian cell-based screening a must.
- Organizational skills and attention to detail highly-valued.
- Must be capable of working with a broader research team and demonstrate good communication skills

To apply for this position, please CLICK HERE

Responsibilities:

Major focus on enabling successful drug discovery programs arising from target biology and an understanding of fundamental disease mechanisms. Manages internal programs as Research Project Leader. Successful candidate should be able to manage interactions across a broad range of disciplines relevant to drug discovery, including chemistry, high throughput screening, pharmacokinetics and metabolism, statistics, and safety pharmacology. Ensures that projects are conducted using best practices as developed within the NSRU.
Evaluates external in-licensing opportunities and collaborations. Supports the Neuro-opportunities group in the evaluation of in-licensing opportunities including working with due-diligence teams. Makes recommendations to the operations group concerning investment in external opportunities based on scientific evaluation of the projects. Identifies academic collaborations that supplement in-house efforts to advance pipeline projects. Evaluates and supports academic collaborations and industry-academia grants.
Enables portfolio delivery by ensuring that scientific strategy and resources are aligned with program milestones; drives both timely and rigorous progress of projects. Ensures that projects are in line with business goals of the NSRU. Ensures that project teams connect effectively with Pfizer business units to understand and drive medically meaningful drug discovery.
Develops scientific strategy for new programs entering the portfolio and ensure strategy for existing programs is updated as new data and science emerges. May be tasked with evaluating, with clinical teams and business units, the repurposing of existing compounds in the NSRU portfolio that have been shown to be safe in the clinic.
Partners effectively across the NSRU. Interacts with Department Heads of Psychiatry & Behavioral Disorders, Neuro-degeneration & Neurological Disease, and Integrative Neuroscience & Circuitry, Neuro-Informatics, Clinical and corresponding laboratory heads in each Department. Directly interacts with laboratory activities in preclinical drug discovery. Interacts closely with the Neuroscience Portfolio, Strategy and Communications group to ensure alignment for overall portfolio deliverables. Liaise with Pfizer biotechnology units (Rinat, Global Biotherapeutics Technologies, Vaccines, Covex, and Center for Therapeutic Innovation) to exploit the full range of therapeutic modalities for CNS targets.

Qualifications:

• PhD/MD or equivalent in an appropriate scientific discipline such as neurobiology, neuroscience or psychiatry.
• Demonstrated track record of delivery on successful drug discovery programs and development of scientific strategy required for execution.
• Experience with drug-discovery/development project leadership is preferred.
• Track record of working effectively in multidisciplinary teams.
• Ability to effectively facilitate meetings with scientific partners and ensure alignment with Neuroscience RU goals.
• Documented ability to understand, drive, and demand scientific rigor.
• Exceptional operational thinking coupled with strong organization skills.
• Demonstrated success in negotiating the environment of a highly matrix-based organization.
• Excellent communication skills and competency in leadership skills.
• Possesses a detailed knowledge of the pharmaceutical research and development process.
• Specific knowledge of Pfizer's approaches within Worldwide Research and Development a plus.

Equal Employment Opportunity:
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act.

All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site.

Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek.

In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer.

To apply for this position, please CLICK HERE

Job Focus:
The Bioanalytical Nucleic Acids group within the BioTx Clinical R&D group focuses on exploratory biomarker analysis for programs within Pfizer's Biotherapeutics (BioTx) organization. This position primarily focuses on the analysis of RNA expression data to discover and validate biomarkers of efficacy and disease/patient stratification to impact Pfizer's Precision Medicine strategy for clinical decision making.

Responsibilities:
- The successful candidate will have a solid understanding of molecular technology platforms (e.g. microarray, TLDA, RNA-seq), and work with biomarker laboratories primarily to help develop and apply cutting-edge technologies to the analysis of data for the stratification of response, classification of disease and related aspects
- In this role, the Analyst is responsible for designing and executing data analysis strategies to investigate human drug efficacy and disease heterogeneity at the molecular level. These strategies support Pfizer's Precision Medicine strategy for patient stratification in the context of drug response
- The analyst will be involved in the design of exploratory analysis plans to identify biomarkers and patients subgroups from interventional and observational clinical patient studies
- The successful candidate will be involved in setting up data QC protocols with CROs, coordinate data transfer and establish potential primary data reduction methods
- Responsible for the implementation, delivery and documentation of computational biology analyses to project teams
- The Analyst will accomplish these goals by leveraging their solid expertise in disease biology, physiology, and working closely with clinicians, basic researchers, and statisticians to integrate gene expression profiling data with a range of other biomarker readouts and related clinical data
- Contribute to information management (LIMS, sample management systems, primary and secondary data) initiatives within BioTx and Pfizer

Qualifications:
- PhD strongly preferred. Masters degree required.
- This role requires skillful experience in the analysis of complex molecular data as well as experience in matrix leadership roles as described below.
- 5+ years of experience in the analysis of complex biomarker data from multiple sources including significant experience with microarray data with a strong emphasis on clinical applications. Experience in the integrative analysis including genetic, cellular and protein data and a deep understanding of disease biology at the molecular level is also desirable.
- Ideal candidate will have experience in a pharmaceutical setting and preferably prior experience in the autoimmune disease drug discovery area.
- Ability to lead biomarker discussions, delineate biomarker priorities in a scientifically rigorous manner while influencing teams is required. Prior experience working in a matrixed environment will also be highly desirable.
- Ability to work in a team environment and rapidly respond to changing priorities. A highly collaborative, innovative mindset, and the ability to communicate complex concepts clearly to diverse audiences such as clinicians and pre-clinical scientist is a plus.

TECHNICAL SKILL REQUIREMENTS:

Equal Employment Opportunity:
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act.

All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site.

Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek.

In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer.

To apply for this position, please CLICK HERE

bluebird bio (www.bluebirdbio.com) is a leading gene therapy company developing breakthrough treatments to transform the lives of people affected by severe genetic disorders. Our proprietary platform addresses the root cause of genetic diseases by placing a healthy version of the human gene into the patient's own extracted stem cells, and then transplanting these corrected stem cells back into the patient. bluebird bio is a clinical-stage company, and has established proof of concept for gene therapy in humans for two indications (Adrenoleukodystrophy and Beta Thalassemia) that illustrate the broad potential of our platform.

Join bluebird bio’s enthusiastic and collaborative Cellular Immunotherapy team by contributing to the overall success of our novel gene-based immunotherapy approach. This new Scientist will join our group to design, develop and evaluate novel cellular immunotherapy approaches for clinical applications. 

Primary responsibilities:

• Design, develop and construct lentivirus vectors to genetically modify freshly isolated hematopoietic cells
• Design and develop approaches to expand, at small and large scale, the gene modified cells in culture.
• Design and develop flow cytometry-based assays to characterize freshly isolated hematopoietic cells and following in vitro culture
• Design and develop  cell-based assays to assess the functional characteristics of genetically modified hematopoietic cells
• Design and develop animal models of cellular immunotherapy to evaluate efficacy and safety of cellular immunotherapies in vivo
• Prepare all technical reports needed in support of an exploratory project moving to process development 
• Exercise independent judgment in development of new methods, techniques and evaluation criteria 

Requirements 

• PhD with 2+ years as post-doc in biology, molecular biology or immunology
• Experience in molecular cloning
• Experience with viral vector or vaccine production is a plus
• Expertise in mammalian cell culture, with specific experience isolating and propagating in vitro culture of human/mouse hematopoietic cells
• Experience with flow cytometry of primary human cells – cell sorting experience a plus
• Experience with immune effector cell functional assays
• Experience in working in animal models of adoptive immunotherapy a plus
• Proven ability to effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines
• Ability to work as part of a team, collaborating with members of other functional groups 
• Understanding of safe lab practices and BSL requirements 
• Excellent computer skills and experience with Microsoft Excel. Flow cytometry data analysis software experience essential 
• Superb organizational and communications, written and oral, skills and “do-what-it-takes” attitude

This is an exciting time to join the field of gene therapy in general, and to become a part of the bluebird bio team in particular.  bluebird bio is a well-funded, privately-held, entrepreneurial company backed by prominent investors and recently named to the 2012 FierceBiotech Fierce 15. We offer a fast-paced, dynamic, collaborative, colorful, and scientifically rigorous environment, with all the fun and passion that a start-up provides, plus an excellent benefits package that include stock options, commuter/parking benefit, etc.

To be considered for this exciting career opportunity, please forward your resume with a cover letter to work@bluebirdbio.com.

bluebird bio, 840 Memorial Drive, Cambridge, MA 02139 www.bluebirdbio.com

bluebird bio will only accept job applications from candidates who are properly documented with authorization to work in the United States.

Note to Employment Agencies: Please do not forward any agency resumes. bluebird bio is not responsible for any fees related to resumes that are unsolicited.

This Part-Time Accounts Payable candidate will be responsible for the entire accounts payable cycle.  In addition he/she will coordinate company’s time reporting and expense reporting systems.  This person will also may participate in the monthly closing and have some General Ledger responsibilities.  This position requires flexibility, a “can-do” attitude, attention to detail and a strong understanding of GAAP.

 Primary Responsibilities 

• Coordinate the accounts payable process from input thru check writing.
• Review and input all vendor invoices
• Enter accounts payable invoices into accounting system
• Research and resolve vendor billing and payment issues
• Cut checks and match with invoices for signature and mailing.
• Assist with the maintenance of the requisition system
• Review and post biweekly project allocation (time reporting).
• Review and post employee expense reporting
• Assist with the monthly close by entering repetitive monthly entries

 Core Competencies

• Solid understanding of GAAP
• High level of attention to detail is critical
• Exceptional organization, communication and multitasking skills required
• Strong knowledge of Excel and Great Plains
• Bachelor’s degree in Accounting or equivalent work experience
• 3-5 years experience in a similar position
• Proficiency with Microsoft Applications is required 

Educational and Experience Requirements

 Interested candidates please send your resume to careers@IntelligentMDx.com

Job Summary:

IntelligentMDx is seeking a legal intern interested in gaining patent law/intellectual property/transactional law experience.  The position will be a part-time paid position (between 15-20 hours per week). The intern will assist our Corporate and Intellectual Property Counsel. Activities will include reviewing and drafting contracts, managing a contracts database, including non-disclosure agreements and corporate documents, researching and drafting memos related to patent and trademark issues, researching company information of potential infringers, reviewing competitive patents, patent applications and products, and interfacing with scientists.

Requirements:

• Completion of at least one year of law school at an accredited institution (2L or 3L)
• A BS/MS/PhD in life sciences/biotechnology is required
• Prior experience or course work in patents/intellectual property is required
• Excellent legal and technical writing skills
• Excellent communication skills and detail-oriented
• Registration to practice before the USPTO is helpful, but not required

 Interested candidates please send your resume to careers@IntelligentMDx.com