Come join our growing team!

Cytrellis Biosystems, Inc. is a clinical-stage medical device company developing powerful new medical devices to improve the quality and appearance of human skin. Our company has developed proprietary technology that harnesses the power of plastic surgery to produce unprecedented results with a minimally invasive, in-office procedure. We are a Boston-based venture capital backed company.

Cytrellis is looking for a strong, creative and hands-on mechanical engineer with a proven track record of new product development from inception to launch. The engineer will be integral to the development of our Company’s platform technology and first-of-a-kind products. In this position, you will be responsible for developing our highly integrated electro-mechanical platform technologies. You will lead the mechanical design, functional testing and customer evaluation of our new product concepts. You will be responsible for establishing and managing relationship with strategic suppliers. This position requires collaboration and the ability to work in a cross-functional environment.  

What skills do you need?

• MS in Mechanical Engineering
• At least 8 years experience in the medical device industry
• Strong track record of mechanical design and testing of electro-mechanical products under design control
• Strong expertise in CAD (SolidWorks is a plus)
• Comprehensive understanding of design for manufacturing (DfM) and design of experiments (DOE) principles
• Experience managing vendors for components design and supply, and product testing

• Understanding of requirements for worldwide commercialization of new medical devices
• Excellent cross-functional collaboration and communication skills
• Proven problem solving capabilities and analytical skills
• Previous experience in the development of products in the dermatology or plastic surgery field, and medical adhesives and dressings is a plus

Cytrellis Biosystems is conveniently located in Boston’s Innovation District. 

For more information, go to: http://www.cwsciences.com/Current-Openings/Animal-Technician-Part-timeInternship---

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

Come join our growing team!

Cytrellis Biosystems, Inc. is a clinical-stage medical device company developing powerful new medical devices to improve the quality and appearance of human skin. Our company has developed proprietary technology that harnesses the power of plastic surgery to produce unprecedented results with a minimally invasive, in-office procedure. We are a Boston-based venture capital backed company.

Cytrellis has an opportunity for a creative, hands-on mechanical engineer to join our growing team. The engineer will be integral to the development of our Company’s platform technology and first-of-a-kind products. In this position, you will be responsible for the design prototyping and testing of highly integrated electro-mechanical solutions. You will contribute to the development and evaluation of our new product concepts. This position requires collaboration and the ability to work in a cross-functional environment.

Desired experience includes:

• MS in Mechanical Engineering or Biomedical Engineering
• At least 2-5 years experience in the medical device industry
• Track record of mechanical design and testing of electro-mechanical products
• Strong expertise in CAD (SolidWorks is a plus)
• Strong experience testing for device feasibility and performance. Familiarity with standard laboratory measurement devices (LabView is a plus)
• Understanding of design for manufacturing (DfM) and design of experiments (DOE) principles
• Proven problem solving capabilities and analytical skills
• Previous experience in the development of products in the dermatology or plastic surgery field, and medical adhesives and dressings is a plus

 Cytrellis Biosystems is conveniently located in Boston’s Innovation District.

For more information, go to: http://www.cwsciences.com/Current-Openings/Civil-Engineer

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

Come join our growing team!

Cytrellis Biosystems, Inc. is a clinical-stage medical device company developing powerful new medical devices to improve the quality and appearance of human skin. Our company has developed proprietary technology that harnesses the power of plastic surgery to produce unprecedented results with a minimally invasive, in-office procedure. We are a Boston-based venture capital backed company.

Cytrellis is looking for a hands-on Clinical Project Manager with a proven track record of clinical trial management. Reporting to the head of Clinical, you provide substantive contribution to the definition of the clinical strategy, clinical study design, planning and outsourcing model in a highly collaborative environment. The Clinical Project Manager leads the execution of a portfolio of studies. You establish and manage relationship with vendors including CROs, monitors, laboratories and bio-statisticians. You are responsible for presenting updates to management teams. The Clinical Project Manager contributes to the continuous improvement of the Company’s processes and procedures and ensures inspection readiness in compliance with internal processes and regulatory requirements.

 Key responsibilities include:

• Development of clinical trial strategy, design and planning of clinical trial.
• Identification of research sites and principal investigators. Performs pre-study visits and is responsible for site qualification. Participates in the final selection of study sites.
• Definition of outsourcing model, identification and assessment of resources including laboratories, monitors, contractors. Responsible for study budget development and oversight.
• Development of clinical trial documentation (e.g. study protocols, informed consent forms, case report forms, study templates).
• Oversight of regulatory approval of clinical trials. Responsible for communicating with IRBs.
• Management of relationship with investigators, oversees investigator meetings.
• Subject recruitment strategy and support as needed.
• Monitoring of study progress. Responsible for tracking and reporting of study deliverables and metrics.
• Oversight of the day-to-day activities of the clinical trial. Ensures quality of study documentation, identifies and coordinates resolution of data deficiencies. Identifies and evaluates issues, coordinates issue resolution. Oversees study logistics. Maintains trial master file.
• Study progress report, formulates improvement recommendations.
• Reporting and documentation of adverse events per internal processes and applicable regulations.
• Study close-out activities, including documentation and resolution of issues.
• Coordination of final study report development and approval.
• Improvement of clinical processes and procedures.

 What skills do you need?

• Bachelors’ degree in scientific/clinical related discipline
• At least 8 years experience in clinical research/operations with significant contribution to the success of a clinical trial, from planning to close-out.
• In-depth understanding of medical device industry requirements and standards including ICH guidelines, GCP and CFR.
• Technical expert in the various aspects of the clinical trial process
• Proficient in development of clinical trial documentation (e.g. protocol, informed consent forms, case report forms, templates)
• Significant experience overseeing day-to-day activities of clinical trials
• Experience managing relationship with vendors, contractors, investigators and IRBs in a clinical trial context
• Excellent cross-functional collaboration and communication skills
• Flexibility to accommodate travel up to 30%
• Proficiency with MS Office suite (Word, Excel, PowerPoint)
• Experience in patient recruitment is a plus
• Previous experience in the development of products in the dermatology or plastic surgery field, and medical adhesives and dressings is a plus

Cytrellis Biosystems is conveniently located in Boston’s Innovation District.

Company Overview:

Chiasma is a late-stage biopharmaceutical company focused on improving the lives of patients suffering from orphan diseases by developing and commercializing novel oral forms of therapies that are available today only by injection. The company’s lead product candidate is octreotide capsules for the orphan condition acromegaly. Chiasma is evaluating additional proteins, peptides and small molecule drugs that are currently only available by injection, but could potentially be converted to oral delivery using the company’s TPE® technology. Chiasma is a public Delaware corporation (Nasdaq: CHMA) with a wholly owned Israeli subsidiary.

The Role:

We are seeking a highly motivated individual to join our growing Finance and Accounting team. This visible role will report to the US Controller and manage the Accounting & SEC Reporting for the company with emphasis on building strong, agile, technical accounting, SEC reporting, and internal controls capability for this recently public company. This individual will have interaction with company leadership (disclosure committee) and key external partners including auditors, outside legal counsel, SOX advisory firm, equity, and tax planning resources. With the support of others in finance, this candidate will manage the coordination and refinement of the monthly and quarterly financial close and reporting processes as we grow as a public company. 

Major Responsibilities:

• Manage SEC reporting processes including drafting of filings 10Q/10K and coordination with company leadership, external auditors, consultants, and legal counsel
• Manage coordination of the monthly and quarterly financial close including developing and refining scalable supporting processes
• Manage refinement of internal controls and Sarbanes-Oxley 404 process and audit
• Manage equity accounting and analytics for stock compensation and EPS
• Manage planning and setup of financial systems, reporting capabilities, and related processes e.g., planning and setup of new entities based on business needs
• Manage the technical memoranda necessary to support accounting treatment positions on matters of revenue recognition, stock compensation, etc.
• Supervisor to the to-be-hired Accounts Payable/Payroll Accountant and Staff Accountant.
• Management of project accounting, and coordination with the US Controller and Director of F,P&A for preparation of the monthly internal financial reporting.

Requirements and Qualifications:

Education:

• Bachelor’s Degree and CPA required

Experience:

• 5+ years relevant accounting experience
• Strong technical skills sought

Skills & Competencies:

• Demonstrated strong interpersonal and supervisory skills and effective in working collaboratively with cross functional team members and with external partners
• Excellent written and oral communication skills 
• Demonstrated ability and willingness to drill-in to operational details while maintaining appropriate whole-company perspective
• Demonstrated strong analytical skills with superior attention to detail
• Demonstrated proficiency with accounting and reporting systems; project accounting experience a plus
• Ability to manage multiple priorities 
• Flexibility to work in a fast paced and dynamic work environment

For more information, go to: http://www.cwsciences.com/Current-Openings/Materials-Manager-cGMP

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

Foundation Medicine is seeking a talented, highly motivated and results-oriented Scientist to join the Molecular Biology and Sequencing group and provide support to clinical and R&D teams. The ideal candidate is a highly collaborative scientist with excellent communication and interpersonal skills, and extensive hands-on experience supporting the late-stage development, implementation and optimization of next generation sequencing assays in a clinical setting. Responsibilities of this position include providing expert, hands-on technical support to the clinical and other teams by developing and maintaining highly collaborative, inter-disciplinary relationships.

• Work with a team of laboratory and computational scientists to support ongoing development and optimization of targeted DNA-seq and RNA-seq clinical diagnostic assays
• Provide technical support for NGS-based clinical assays including hands-on training, delivering presentations, and writing detailed, accurate, and accessible validation/experimental plans, SOPs, and reports summarizing assay performance
• Act as a bridge between operations and R&D teams to support ongoing assay development, optimization and troubleshooting. Deliver timely and innovative solutions to address needs by working collaboratively with inter-disciplinary teams including R&D, Commercial, Clinical, QA and Computational groups.

• Expertise in molecular biology and an in-depth understanding of the practices and principals of NGS, including DNA-seq and RNA-seq protocols, and various target-enrichment approaches (e.g. multiplex-PCR, hybrid selection); expertise working with and developing robust protocols for high throughput laboratory automation is preferred
• Experience working in a dynamic multidisciplinary environment with quickly changing priorities
• Demonstrated ability to effectively communicate, both written and verbal, scientific concepts, experimental plans and results
• Ability to work independently and collaboratively in a dynamic, fast paced team environment to design, plan and execute experiments

• Development, validation and implementation of CLIA-certified tests including writing SOPs and validation plans/reports
• Experience working with typical oncology specimens (e.g. FFPE, Blood, Bone Marrow)
• Basic NGS data management and analysis (e.g. SAMtools, IGV/Picard, Python/Perl)

• PhD, or equivalent, in Molecular Biology, Biochemistry, Genetics, Cancer Genomics is preferred
• Minimum 3-4 years working in Industry and/or Academia

Apply Here

PI92149764

Senior Administrative Assistant

Location: Cambridge, MA

Kanyos Bio is searching for an Senior Administrative Assistant to provide excellent administrative support to the Kanyos senior management team.  This individual will work with a high degree of autonomy and manage work with a high degree of autonomy and manage multiple administrative tasks for several executives, as well as assist the entire Kanyos team in our general operations. The individual will gain a unique experience working with colleagues in Europe and Asia, and become an essential part of a cutting-edge immunotechnology company striving to deliver therapies for patients with autoimmune disorders.

Responsibilities:

The successful candidate will provide various levels of support to the entire organization, and accomplish the following responsibilities:

• Supporting several executives with calendar management, expense reporting, and travel arrangements
• Answering telephones and screening calls as appropriate
• Scheduling meetings and teleconferences, including scheduling conference rooms, managing A/V needs and coordinating catering
• Prioritize and manage multiple projects simultaneously, and independently follow-through on issues in a timely manner
• Expense reconciliation and reporting using various electronic expense report systems
• Greeting and welcoming partners, visiting scientists, collaborators and other guests
• Administrative activities such as data entry, photocopying, scanning documents and filing

• Establish procedures and monitor document management and record keeping, including ensuring confidentiality of data
• Lead all office management activities, including supplies and coordinating external service providers

Qualifications:

• Bachelors degree and at least 5 years of experience with demonstrated mastery of all secretarial and administrative skills, at an executive level
• Excellent communication skills: written composition, oral, and interpersonal
• Exceptional attention to detail, follow-through and interpersonal skills
• Strong knowledge of software for office operations, including MS Office and Lotus Notes
• She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to a fast-paced entrepreneurial environment.

Contact:

To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KEA-01-2015-08)

Applicants should be legally entitled for employment in the United States.

Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale Lausanne) in Switzerland with our sister company, Anokion.  Kanyos and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.

For more information, go to: http://www.cwsciences.com/Current-Openings/Research-Associate-Microbiology

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

For more information, go to: http://www.cwsciences.com/Current-Openings/QC-Documentation-Specialist

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

For more information, go to: http://www.cwsciences.com/Current-Openings/Microbiology-Associate

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

For more information, go to: http://www.cwsciences.com/Current-Openings/Manufacturing-Associate-GMP

Candidates must live local and be a US Citizen or Green Card Holder

Email resume to: jobs@cwsciences.com

Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

Commonwealth Sciences, Inc.

www.cwsciences.com

Alnylam Pharmaceuticals, Inc. is seeking an experienced corporate/life sciences paralegal to join the legal department in Cambridge, MA.

Opportunity to join a dynamic legal department in a growing biotechnology company, responsible for public company and state licensing related matters and supporting corporate governance, as well as the growth of our European operations as Alnylam moves towards commercial launch of its first product.  This position reports directly to the Vice President, Associate General Counsel.

Responsibilities include: Manage and maintain board and committee related materials from the legal department, including meeting materials and minute books.  Lead formation of domestic and international subsidiaries, and maintain associated corporate books and records.  Support preparation and filing of all SEC filings, including periodic and current reports, proxy statements, Section 16 reports and confidential treatment requests.  Assist in development and maintenance of corporate governance policies and guidelines. Prepare, file and maintain all state qualifications to do business, annual reports and business licenses, including manufacturing and distribution licenses, as applicable.  Occasional support of litigation efforts, due diligence and responses to third party inquiries. Partner with Corporate Communications department to ensure company's public website is current and compliant with legal requirements for public companies.  Maintain legal department's intranet site; and assist in development and maintenance of templates, training and communications materials.

The following skills and experience are essential for a strong candidate:

• Experience with SEC reporting and NASDAQ compliance requirements.
• Experience with Delaware corporate governance requirements
• Excellent drafting and proofreading skills, with the highest attention to detail.
• Excellent organizational and time-management capabilities demonstrated through ability to coordinate multiple projects and priorities simultaneously, as well as a strong sense of project ownership.
• Ability to maintain confidential information.
• Strong oral and written communication skills.
• Strong interpersonal skills and the ability to communicate effectively throughout all levels of the organization as well as with external parties.
• Ability to work independently.

The ideal candidate will have 5-7 years of legal experience, including independent work in relevant areas including: public company reporting, corporate governance matters, subsidiary formation and maintenance, and evaluation, application and maintenance of state licenses for a life science company.  Life science industry experience and experience interacting with international subsidiaries preferred.

Educational background: Bachelor's degree and/or formal paralegal training and certification combined with significant work-related experience in a law department or law firm.

Alnylam Pharmaceuticals is an Equal Employment Opportunity (EEO) employer committed to an exciting, diverse, and enriching work environment. 

About ImmunoGen, Inc.

ImmunoGen, Inc. develops targeted anticancer therapeutics. The Company’s ADC technology uses tumor-targeting antibodies to deliver an ImmunoGen cell-killing agent specifically to cancer cells. The Company utilizes its ADC technology with its antibodies to create ImmunoGen product candidates and also out-licenses limited rights to use its technology to other companies. Roche's Kadcyla® is the first marketed product with ImmunoGen's ADC technology. More information about the Company can be found at www.immunogen.com.

Kadcyla® is a registered trademark of Genentech, a member of the Roche Group.

We are a nimble HR Team at the forefront of high growth as the company works to deliver innovative anti-cancer therapies that meaningfully improve the lives of patients.  The Human Resources Business Partner is responsible for assisting with the execution of HR strategies globally for part of a Line of Business (LOB), business segment or location with oversight by the Executive Director, Talent Acquisition. The person in this role should have strong business acumen with proven ability to align business needs with HR support and solutions to move the business forward in a growing and changing environment.  This position understands the overall needs of the business and proactively implements HR strategies to support business goals and growth. The HR Manager - collaborates with HR Centers of Excellence to manage and coordinate all facets of HR to help the business achieve its goals. This position is responsible to drive for results and utilize metrics that enhance organizational effectiveness, managerial capability, talent development and succession planning for the LOB for respective client groups or population.

 Key Responsibilities to include:

Strategic Business Partnership

• Understand and anticipate the client needs and develop HR strategies, in line with business goals.
• Consult with line management, providing HR guidance on organizational design, change management, workforce & succession planning programs.
• Establish and build strong relationships with the senior leaders in a Line of Business to deliver business aligned HR solutions that are congruent with business goals and objectives.
• Execute HR strategies and/or priorities which support business goals as appropriate for respective areas.
• Assist in the development of a comprehensive talent strategy, supported by succession plans to ensure the current and future caliber of talent needed to support the business, is in place.
• Help implement the organizational design of the LOB and create an HR framework, which proactively supports business growth.
• Collaborate and support LOB Partners and or leadership on the Performance Management program and annual compensation cycle, to ensure decisions are performance based and consistent with talent development goals.
• Provide guidance and coaching to LOB management and or local leadership to increase effectiveness and global cohesiveness.
• Support client leadership on Performance Management program and annual compensation cycle to ensure decisions are consistent with overall business strategy.
• Work closely with management and employees to improve work relationships, build morale, increase productivity and retention.

Change Management

• Provide change management to guide leadership on how to effectively navigate new HR programs and/or policies, as needed.
• Execute on change management plans for client, as needed, to support changes to the organization structure, implementation of business strategies, introduction of new business practices, etc.
• Provide guidance and counsel to an organization in the midst of organization change and shifting directions.

                Leadership Coaching:

• Deliver both solicited and unsolicited leadership feedback to managers and other senior leaders. Provide coaching, as needed, to address issues.

HR Partnership

• Escalate issues and feedback to Sr. HRBP and/or appropriate HR area leader as appropriate on effectiveness of programs and policies.

• Works with HR Centers of Knowledge on the development and execution of HR programs aligned to the needs of the client or location they support.
• Works with Sr. HRBP and others within HR Centers of Knowledge including Compensation, HCM, Training & Development and HRDirect to ensure HR Services are aligned to provide for the needs of the business

Employee Relations

• Provide advice and counsel to Managers and Supervisors regarding personnel practices, policy, and employment laws:    ensuring compliance with all employment regulations based on site/country legal requirements
• Guide line leaders in developing role profiles for hiring and promotion consideration; partner with compensation team for job evaluations
• Coach managers and associates in their own development and how to have development discussions
• Perform onboarding meetings with new hires to reinforce early development identified in recruiting process and with     new supervisors to inform about HR cycle and processes
• Support line managers and associates through Performance Management challenges including development and implementation of performance improvement plans
• Employee advocate whilst at the same time working to minimize company liability
• Support associates and line managers through voluntary termination events; answering questions and providing information regarding impact to benefits and pay; directing to HRIS support
• Advise, support and coach leaders through involuntary termination transactions
• Handle challenging employee relations incidents such as those escalating to the Novartis Business Practice Officer
• Practice mediating activities with line organizations
• Escalate/consult on performance or termination transaction activities with legal
• Manage the ADA Interactive Process, providing information and support to both the associate and supervisor

Required Qualifications:

• Strong Business Acumen and working knowledge of multiple human resources disciplines; including but not limited to compensation, benefits, talent/performance management, employee engagement, reward and recognition principles and federal and state respective employment laws.

• Comprehensive knowledge of strategic planning, organizational effectiveness, talent development, succession planning and leadership effectiveness
• Ability to translate business vision and strategy into an executable HR and business goals.
• The ability to work independently with minimal supervision, interact with staff (at all levels) in a fast paced environment
• Able to command respect at all levels of the organization, capable of highly-independent work as well as being a team player and role model
• Excellent verbal and written skills, able to lead open and effective dialogue throughout the Company and able to craft and deliver compelling messages internally.
• Demonstrated track record of proactively suggesting new alternatives to current HR practices, anticipating and developing both strategic and tactical HR plans and programs to accomplish the Company’s mission
• Experience in most or all of the functional areas associated with this position; excellent management, negotiating and organizational skills; demonstrated ability to achieve results
• High energy level, a driving sense of urgency and a seasoned “make it happen/can do” orientation.  Exceptional relationship management and interpersonal skills developing, building and maintaining strong business partnerships
• Proven ability to effectively interact with all levels of the organization, particularly senior management

Education or Experience:

• 7-10 years HRBP or Generalist experience. PHR/SPHR a plus.
• Bachelor’s degree in Human Resources or equivalent/similar, in Biotech or pharmaceutical environment experience preferred.
   

ImmunoGen, Inc. is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status.

ImmunoGen, Inc. does not accept non-solicited resumes or candidate submittals from search/recruiting agencies not already on ImmunoGen, Inc.’s approved agency list. Unsolicited resumes or candidate information submitted to ImmunoGen, Inc. by search/recruiting agencies not already on ImmunoGen, Inc. approved agency list shall become the property of ImmunoGen, Inc. and if the candidate is subsequently hired by ImmunoGen, Inc., ImmunoGen, Inc. shall not owe any fee to the submitting agency.

Key Responsibilities
Completes both animal husbandry and cagewash/facility duties according to standard operating procedures. These duties include, but are not limited to, providing clean sanitized caging material, fresh food and water and environmental enrichment on a scheduled and as needed basis.

Position Details
- Monitors animal health and well-being. Evaluates animal health, reports abnormal conditions, monitors and provides clinical treatments as directed by veterinarian, program management or designee and administers special water solutions and diets as directed by research protocols.
- Documents, organizes and maintains timely records in the laboratory animal resource software system.
- Ensures compliance with required regulations and consistently follows program and institutional procedures and policies.
- Operates bio-safety cabinets, animal transfer stations, individually ventilated rack systems and humane euthanasia equipment.
- Assists with preparing autoclaved caging material for animal colonies according to standard operating procedures.
- Completes cage, rack and equipment sanitation, sterilization and preparation.
- Processes all animal cage components & related equipment through mechanical cage, bottle, rack or tunnel washers.
- Performs quality assurance monitoring and record-keeping to ensure proper sanitation.
- Operates mechanical cagewash units, bulk steam sterilizers, decontamination equipment and material-transfer vacuum systems according to standard operating procedures and manufacturer instructions.

Requirements:
- High School diploma or GED and 1-3 years employed in a laboratory animal husbandry position.

- Ability to communicate effectively and professionally with research staff.
- Weekend and holiday work required. AALAS certification preferred.
- Must function well independently and as a team-member.

This position qualifies as an essential employee. Employment is conditional upon the satisfactory completion of an occupational health assessment for working with laboratory animals.

- Must have the ability to lift 50 lbs. and push/pull 300lbs.

The Broad Institute will not offer visa sponsorship for this opportunity.

EOE/Minorities/Females/Protected Veterans/Disabilities

To apply for this position, please CLICK HERE

We are seeking a highly motivated Computational Biologist with a strong background in “big data” approaches to experimental genomics to join our multidisciplinary drug discovery team. We are a group of experts in biochemistry, genomics, cell biology, and clinical medicine focused on transforming the treatment of rare metabolic disorders. The successful candidate will play an essential role on the team, helping to determine which target pathways are given the highest priority. This position requires a strong background in computational genomics (e.g., genome sequence analysis, ChIP data analysis, RNA-seq analysis, statistical genetics) with an ability to analyze newly generated data in the context of what is in the public domain. The ideal candidate will be an enthusiastic and organized individual who enjoys a fast-paced, team-based approach to discovery. Attention to detail and excellent communication skills are a must. There will be ample opportunities for co-authorship on high-impact papers

PRINCIPAL DUTIES AND RESPONSIBILITIES
- Analyzes large-scale data sets generated by an experimental team, including genome-wide CRISPR screens, RNA profiling, and metabolomics in the context of publicly available data sets
- Presents the results of data analysis to the entire team in a clear manner
- Readily adapts to new data sets by modifying existing analysis tools and developing novel approaches
- Plans and executes projects independently, identifying and resolving technical and methodological problems as they arise
- Trains, supervises, or mentors junior computational staff as needed

QUALIFICATIONS
- Ph.D. in a quantitative discipline (such as computer science, bioinformatics, physics; or in biology with a strong quantitative background) is required.
- Extensive background in data analysis (multivariate statistics, statistical inference, regression analysis) and genomics (bioinformatics, analysis of genomic information)
- Strong programming skills, including scripting, databases, and scientific computing
- Record of high impact research publications and scientific presentations
- Demonstrated ability to develop and shift plans to adjust to rapidly changing scientific priorities and technologies
- Excellent communication (both in writing and presenting), analytical, and interpersonal skills
- Outstanding organization and time management skills
- Ability to build excellent working relationships and foster collaboration in a team environment

EOE/Minorities/Females/Protected Veterans/Disabilities #LI-POST

To apply for this position, please CLICK HERE

Org Marketing Statement
All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That's why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.

Role Description
We seek a highly motivated individual with Ph.D. in systems biology/pharmacology modeling, biochemical engineering or other related field and a demonstrated track record in scientific publication. The postdoctoral fellow will be located in Cambridge (MA), a world-class center of pharmaceutical and biotech research. The individual will build quantitative systems pharmacology model(s) to yield an understanding of how inhibition of Janus Kinase (JAK) pathways correlates with efficacy and safety observations and to inform target selection and clinical trial design. The individual will work in a highly stimulating and multi-disciplinary environment and will have interactions with biologists, precision medicine scientists, clinical pharmacologists, clinicians and systems pharmacology modelers. In addition to building computational models, the individual will also have an opportunity to influence experimental designs towards data generation.

Responsibilities
* Create a multi-scale systems model describing inhibition of JAK pathways based on literature data and in-house information
* Develop linkage between in vitro JAK selectivity and resulting in vivo biomarker responses
* Apply data mining tools to obtain information on intracellular pathways relevant to inflammatory diseases
* Identify relevant data (in-vitro, in-vivo preclinical and clinical trial data) for model identification, optimization, and validation
* Design experiments aimed towards generating data for model validation and testing of relevant hypotheses
* Effectively communicate model results and outcomes to scientists in non-quantitative disciplines
* Write scientific publications and present at internal and external scientific meetings

Qualifications
* Ph.D. degree in mathematics, engineering or other disciplines related to quantitative pharmacology or equivalent experience with a strong emphasis on biopharmaceutical modeling and simulation.
* Previous experience in building systems biology/pharmacology models, including ordinary differential equation (ODE) based models is required.

TECHNICAL SKILLS REQUIREMENTS
* Excellent understanding of theory, principles and statistical aspects of advanced mathematical modeling and simulation
* In depth, hands-on knowledge of the state of the art modeling and simulation software and applications in the area of PKPD and systems modeling and simulation (i.e. MatLab, Simbiology toolbox, S-plus, R or comparable applications)
* Capable of rapidly and efficiently building implementing ODE based models of biological systems, and applying parameter estimation and optimization techniques
* General familiarity with modeling techniques beyond ODEs, e.g. partial differential equations, Bayesian modeling, population modeling will be a plus
* Proven track record in scientific communication and writing manuscripts
* Good understanding of in vivo animal models and drug discovery process is a plus

EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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Org Marketing Statement
A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description
We are seeking a Senior Associate Scientist to join our PDM Assay Development team in Andover, MA. The Senior Associate Scientist will be responsible for the development and qualification of robust and reliable ligand binding assays suitable for characterizing the disposition and immunogenicity of biotherapeutics and quantitation of biomarkers in various matrices using a range of potential screening platforms and assay techniques.

Responsibilities
Responsible for the design, trouble shooting, qualification and conduct of the assay to support biotherapeutic programs.
Timely delivery of concentration and immunogenicity data to PDM BioTX principal investigators and other partners. Advancing bioanalytical capabilities to improve efficiency, cost effectiveness and appropriateness of assay for discovery and development stage assets.
Design, develop and implement ligand binding assays (e.g. ELISA, MSD, Gyrolab) to measure protein of interest concentration (drug and/or biomarker) and detect the presence of anti-drug antibody in a fast paced and dynamic environment.
Perform data analysis and interpretation and be able to draw conclusions regarding progress and results of work, utilizing the data in appropriate decision making.
Gathers input from colleagues, literature, and additional resources to assist in driving the project forward.

Qualifications
*BSc with at least 3+ year's relevant experience, with a focus on ligand binding assay development; (R2); MSc with at least 2+ years relevant experience with a focus on ligand binding assay development (R3).
*Industry experience with a focus in biotherapeutics and a strong record of scientific achievement; excellent communication skills.
*Proven track record in the area of biotherapeutics bioanalysis with understanding of a broad range of bioanalytical platforms. Proven presentation skills.
*Knowledge and hands-on experience developing ligand binding assays, utilizing various platforms and demonstrated analytical problem solving skills.
*Broad understanding and skill in areas of bioanalytical laboratory techniques for biotherapeutics (knowledge of ligand-binding assays is essential; skills in other areas such as LC/MS, flow cytometry, cell-based assays, reagent characterization is a plus)
*Proven ability to generate high quality data against challenging time lines
*Ability to communicate across site and discipline to enable maximum impact of bioanalytical science.
*Knowledge of biotherapeutic structure, pharmacology, disposition and immunogenicity and the impact on assay selection.
*Ability to author technical documents such as data summary reports and analytical procedures. Collaborative skills and effective partnering skills in a complex, multi-discipline organizational model.
*Strong organizational and time management skills in order to balance working on multiple projects in parallel.

EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Application URL:http://www.aplitrak.com/?adid=QWxpc29uLlR1dGx5cy44Njk0NS4zMTY3QHBmaXplci5hcGxpdHJhay5jb20

Org Marketing Statement
A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description
A Principal Scientist position requiring a Ph.D. degree is available for a highly motivated and creative candidate with a strong background in immuno-oncology and tumor cell biology to join the Bioconjugates Group in the Oncology Research Unit. The successful candidate will have an opportunity to establish their own lab and expected to develop a research program in immuno-oncology. The ideal applicant will have extensive experience in cancer research, immunology, or related fields, and a desire to continue in a laboratory-focused role. The candidate will have a proven track record of scientific productivity as evidenced by first author publications in prominent journals and ability to participate in a highly matrixed and innovative research environment. The individual will have a leadership role who participates in strategic discussions, establishes external collaborations, mentors/manages other scientists, coordinates program activities, and aligns stake holders from partne
r lines to meet timelines and advance the program through the pipeline. Candidate should be able to translate basic research findings into novel therapeutic strategies that support clinical drug development.

Responsibilities
*Independently design and execute experiments using in vitro biochemical and cell-based assays to investigate target biology and therapeutic mechanisms of action.
*Participate in oncology target identification and validation.
*Demonstrate a high level of initiative in troubleshooting experiments and performing data analysis.
*Effectively collaborate with other members of the Oncology Research Unit and supporting partner lines.
*Present findings to project teams and governance bodies, prepare technical reports, and contribute to regulatory filings.
*Conduct research that leads to publication in peer-reviewed journals and presentation of data at internal and external meetings.

Organizational Relationships:
This role will have interactions with colleagues in the Oncology Research Unit, Bioconjugates Discovery and Development and Global Biological Technologies, Worldwide Medicinal Chemistry, Pharmacokinetics Dynamics & Metabolism, and Drug Safety R&D.

Supervision:
Position requires direct management of 1-2 colleagues plus project coordination with multiple scientists from various partner lines to advance their research and therapeutic compounds through the pipeline.

Qualifications
*Ph.D. degree in Immunology, Cancer Biology, Cell Biology, Molecular Biology, Biochemistry, Pharmacology or related field with 4+ years of postdoctoral or combined industry experience, plus a solid background in tumor biology, immuno-oncology and/or biologic-based therapeutics. Experience in innate immunity a plus.
*Strong research experience in RNA/protein techniques, antibody, immunotherapy and/or antibody drug conjugate characterization.
*Excellent communication skills, both written and oral, and highly organized in terms of goal-setting and achieving.
*Expertise and hands-on experience with mammalian cell culture, flow cytometry, FACS, immunofluorescence, spinning disk confocal microscopy, si/shRNA-mediated gene knockdown, ELISA, IHC and cell culture techniques.

EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Application URL:http://www.aplitrak.com/?adid=SmVzc2ljYS5Fc2NvdG8uODEzOTcuMzE2N0BwZml6ZXIuYXBsaXRyYWsuY29t