Job Responsibilities/Department Description:
The candidate will join Process Analytics (PA) department, Late Stage Process Development (LSPD). The candidate will provide in-process sample testing using a variety of analytical assays to support cell culture, purification development and fill finish development groups.
Responsibilities:
·Provide analytical sample testing to support upstream and downstream process development activities within LSPD departments. Provide assay results in a timely manner. Follow Standard Operating Procedures (SOP) rigorously and trend assay controls and instrument performances
·Support assay investigation associated with analytical testing activities.
·Transfer and implement assay in Process Analytics; perform comparability studies and document assay transfers
·Participate in high throughput assay development under manager’s supervision. Write experimental protocols; consult with supervisor for guidance and approval.
·Document experiments, results and findings in laboratory notebook; presents work at the group and department meetings; participates in the writing of technical reports, SOPs, and analytical method protocols, etc.
Basic Qualifications:
·Bachelor’s Degree and 5-8 yrs. or Master’s 3-6 yrs. experience.
·Technical expertise and knowledge through experience and application; hands-on with the following techniques: HPLC/UPLC (R. Phase. SEC, affinity etc.), electrophoresis (CGE, cIEF, native and denaturing SDS-PAGE gel systems); antibody based assays (Western blotting and ELISA) and protein quantitation assays
Preferred Qualifications:
·Skilled in protein sample handling, storage, and preparation ·Participates in general lab activities to maintain lab infrastructure (e.g. lab organization, assay control inventory, chemical inventory, instrument log maintenance etc.).
·Maintain accurate and up to date notebook records.
·Analyze and present data in a clear fashion. Summarize assay results in technical presentations/reports.
·Ability to learn new technologies fast with good problem-solving skills.
·Good fundamental understanding of protein biochemical assays and process analytics.
·Advanced knowledge of Microsoft Excel; Proficient in Microsoft Word, Power Point
Excellent communication and interpersonal skills; high attention to detail. Must be able to work in a team-oriented environment