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Career postings for the Massachusetts Biotechnology Council

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    For more information, go to: http://www.cwsciences.com/Current-Openings/Research-Associate-Cell-Culture

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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  • 10/30/15--00:50: Pharmacovigilance Manager
  • For more information, go to: http://www.cwsciences.com/Current-Openings/Pharmacovigilance-Manager

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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    For more information, go to: http://www.cwsciences.com/Current-Openings/Sr-Research-Associate--Immunology

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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  • 10/30/15--00:56: Jr. Buyer
  • For more information, go to: http://www.cwsciences.com/Current-Openings/Jr-Buyer

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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    For more information, go to: http://www.cwsciences.com/Current-Openings/Quality-Engineer-Client-Liaison

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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  • 10/30/15--01:01: QA Associate
  • For more information, go to: http://www.cwsciences.com/Current-Openings/QA-Associate

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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    For more information, go to: http://www.cwsciences.com/Current-Openings/Scientist--IVD-Assay-Development

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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    For more information, go to: http://www.cwsciences.com/Current-Openings/Scientist-HighThroughput-Screening

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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    GENERAL SUMMARY OF POSITION:

    Under the supervision of the Principal Investigator or designee, the Research Laboratory Technician I, performs a variety of specimen preparatory techniques, dry lab data collection, and routine laboratory maintenance.

     

     

    MAJOR RESPONSIBILITIES:

    • Perform a variety of laboratory experiments using both routine and special techniques and methods
    • Assist in more complex laboratory tasks
    • Collect, analyze, and process laboratory samples
    • Record results, organize data, and perform basic computations
    • Maintain laboratory supplies and equipment
    • Comply with all safety and infection control standards
    • Perform other duties as required.

     

    REQUIRED QUALIFICATIONS:

    • Bachelor’s degree in Biological Science or equivalent experience
    • Knowledge of Microsoft Office products
    • Ability to perform duties independently
    • Judgment and action skills required to solve commonly encountered problems

     

    PREFERRED QUALIFICATIONS:

    • Work with laboratory animals
    • Experience with cell culture techniques
    • Experience handling mice is preferred

     

    SUPERVISION RECEIVED:

    Under the supervision of the Principal Investigator or designee

     

    SUPERVISION EXERCISED:

    None

     

    ENVIRONMENTAL WORKING CONDITIONS:

    Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.



    Apply Here

    PI92211380


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  • 10/30/15--01:16: Research Associate
  • For more information, go to: http://www.cwsciences.com/Current-Openings/Research-Associate

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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  • 10/30/15--01:23: Clinical Supply Coordinator
  • For more information, go to: http://www.cwsciences.com/Current-Openings/Clinical-Supply-Coordinator

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


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  • 10/30/15--02:08: Technical Writer
  •  

    Technical Writer II         

    Hours Full Time         

    Position Summary

    Job Description: 
    Responsible for coordination, development and writing of tech transfer documentation for Client projects at the manufacturing facility, including, but not limited to: 
    • Standard Operating Procedures (SOP) 
    • Manufacturing Batch Records (MBR) 
    • Formulation Preparation Records (FP) 
    • Protocols 
    Job Duties: 
    • Create templates and/or initial drafts for new documentation and work with PD, PTS and Manufacturing on incorporating technical content. 
    • Incorporate changes into document revisions resultant from document review process (initial draft reviewer’s comments and Attachment 2 comments), buffer run red lines, engineering run red lines, and tech transfer changes management process. 
    • Work with PTS and Manufacturing on reviewer’s comments resolution and provide feedback on any conflicting comments. 
    • Manage document revisions and maintain records of document changes through tracked changes of documents and spread sheets. 
    • Relay information to PTS and Manufacturing regarding conflicting comments between reviewers. 
    • Provide document status updates for scheduling purposes. 
    • Provide thorough review of documentation written by others, including review of post review reports. 
    • Ensure that documentation formatting is consistent with governing SOPs, and ensure that use of terminology and content within and between documentation is consistent. 
    • Review SOPs and Batch Records for alignment.         

     Requirements

    Education & Experience Requirements: 

    BS in Life Sciences or Engineering with 10+ years experience.


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    If interested and qualified, please include Req #2015-011 in the subject line when emailing resume tocareers@InotekPharma.com.

    Position Summary

    This person will lead the development and rollout of corporate branding messages across multiple communications channels and platforms.

    Responsibilities

    • Ability to develop a communication strategy, key messages and tactical execution plans.
    • Ability to write, review and edit documents, applying universal grammatical and editorial rules and standards as well as the company’s standards. Ability to distill complex language into easy-to-understand, grammatically correct language in an active voice and to quickly synthesize information from a variety of sources (internal and external) into one effective output.
    • Write, with little or no supervision, articulate, persuasive documents that compel the reader to think or act differently.
    • See all angles and versatility to address many different audiences; position messages appropriately to influence broader opportunities.
    • Ability to develop and leverage internal and external thought leader and advocate relationships to reinforce the company's messages, support products and market position, and promote ongoing relationship building and management.
    • Ability to recognize key data points, plan for and anticipate questions and conduct interviews to elicit/probe for appropriate information.
    • Ability to prepare and probe for information and apply reporting and facilitation techniques.
    • Technical knowledge of production process for the development of communication collateral materials.
    • Ability to identify and analyze business and audience needs to deliver messages via the most appropriate mix of media and channels as well as understand channels and vehicles available internally and externally.
    • Ability to counsel on regulatory requirements relevant to communication about and promotion of products.
    • Partner successfully with investor relations to ensure consistency of messages to external audiences including media and financial world

    Minimum Qualifications

    • Bachelors degree in public relations, communications, journalism or related field
    • Experience working in-house or within a PR agency
    • Proven ability to create and build a company brand and oversee Corporate Communications activities including Annual Report and Annual Meeting
    • 5 years of industry experience in Biotechnology, pharmaceutical or healthcare product public relations
    • Policy experience or crisis management experience are highly desirable
    • Strong oral and presentation skills; expert skills in PowerPoint
    • Ability to negotiate and persuade
    • Superior writing skills and proven media relations skills that are results-oriented
    • Strategic and creative thinker with ability to develop actionable programs that integrate soundly with business objectives
    • Ability to work on multiple projects simultaneously
    • Ability to productively navigate a challenging and dynamic environment, and deal with rapidly changing priorities
    • Ability to interact with all levels of management and vendors
    • Ability to think quickly, analytically and creatively to accommodate a dynamic communications environment
    • Excellent interpersonal skills; enthusiastic, team player and self-starter; serious commitment to hard work and excellence
    • Healthcare Industry experience required, preferably with specific experience working with the scientific communications; mix of agency and corporate experience preferred.
    • Experience and/or knowledge of multiple communications tools, including; web-based videos and social media.

    If interested and qualified, please include Req #2015-011 in the subject line when emailing resume tocareers@InotekPharma.com.

    Competencies

    • Adaptability / Perseverance– The ability to adapt to working effectively within a variety of situations; adapts enthusiastically to organizational change and to changes in job demands.  Shows initiative and demonstrates learning orientation and flexibility. Pursues tasks with energy, drive and enthusiasm, even in the face of adversity.
    • Communication and Teamwork– The ability to effectively express ideas in written, visual, and oral context.  The ability to work co-operatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.
    • Creativity/Innovation - creating a boundary-less environment that fosters curiosity and taking risks, openness to new approaches, diversity of new thought, blank page creativity and opportunistic thinking.
    • Job Knowledge– Achieves and maintains technical and professional proficiency related to current job position and areas of expertise.
    • Passion - create an exciting environment where there is the passion of academia with the discipline of industry where there is true intellectual exchange and ideas are challenged effectively.
    • Results Orientation / Productive Work Habits– Drives issues to closure and gets the job done.  Skilled at analyzing scope of work, as well as planning and executing a successful outcome.  Understands and assigns / utilizes resources effectively and efficiently.

    Company Overview

    Inotek Pharmaceuticals is a clinical-stage, publicly traded, biopharmaceutical company focused on the discovery, development and commercialization of novel therapies to treat glaucoma and other serious diseases of the eye. Our common stock is listed on the NASDAQ Global Market under the symbol "ITEK."

    Glaucoma is a disease of the eye that is typically characterized by structural evidence of optic nerve damage, vision loss and consistently elevated intraocular pressure, or IOP. Our lead product candidate, trabodenoson, is a first-in-class selective adenosine mimetic.

    This molecule was developed to selectively stimulate a specific adenosine subreceptor, and was developed initially to prevent apoptosis following ischemia-reperfusion injuries such as stroke or myocardial infarction. In the eye, stimulation of this same receptor has the effect of augmenting the intrinsic function of the eye's trabecular meshwork, or TM, which is the main passageway for transporting the aqueous humor, a liquid that maintains the eye's shape and typically experiences elevated pressure in glaucoma. We believe that by enhancing this naturally occurring TM process, rather than changing the fundamental dynamics of pressure regulation in the eye, trabodenoson's mechanism of action should result in a lower risk of unintended side effects and long term safety or tolerability issues. Additionally, trabodenoson's unique mechanism of action in the TM should complement the activity of existing products that lower IOP by addressing different parts of the in-flow and out-flow system of the eye.

    Trabodenoson has completed Phase 2 clinical development in primary open-angle glaucoma (POAG) and ocular hypertensive (OHT) patients and is ready for Phase 3. Trabodenoson, if ultimately approved by regulatory agencies, will be a valuable, innovative product that ophthalmologists can use alone or in combination with other approved medicines for glaucoma, and would also be a new treatment option for those patients who are refractory to current drug therapies.

    The neuroprotective potential of trabodenoson is supported by the basic biology of adenosine, which has shown that stimulation of the A1 receptor by endogenous adenosine protects tissues of the central nervous system. A pre-clinical study of the impact of high IOP on retinal ganglion cells showed that trabodenoson could protect this key population of cells in the retina that, when lost, results in the irreversible vision loss. A preclinical program investigating a number of currently untreatable degenerative retinal diseases that would benefit from the neuroprotective action of trabodenoson is ongoing with the goal of supporting proof-of-concept clinical trials.

    Inotek, in addition to having built a potential first-in-class ophthalmic product candidate in trabodenoson, has an experienced management team with a track record of multiple successful NDA approvals and successful product launches. Inotek intends to advance its programs through regulatory approval and to market its ophthalmology products, a specialty area, with a relatively small and focused sales and marketing team. The Company is based in Lexington, MA.

    For more information, please visit www.InotekPharma.com

    If interested and qualified, please include Req #2015-011 in the subject line when emailing resume tocareers@InotekPharma.com.

    Inotek Pharmaceuticals Corporation is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.


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    KEW is seeking a Senior Scientist to be part of a team that researches and critically assesses scientific literature to develop written summaries related to tumor and cancer genetics, biomarkers, therapeutic development, and clinical trials to be used in patient laboratory reports. You will play a central role in helping to build our knowledge management and curation team and will be a part of a collaborative team that thrives on scientific discussion. This is a unique opportunity to be part of a growing company that is having significant impact on cancer patients and cancer care.

    PRINCIPAL DUTIES AND RESPONSIBILITIES:

    - Functional analysis of cancer‐associated mutations;

    - Work with a multidisciplinary team including practicing oncologists, scientific thought leaders, and laboratory professionals to develop and maintain the KEW knowledgebase;

    - Research, critically assess, and provide written summaries of scientific literature related to tumor and cancer genetics, biomarkers, therapeutic development, and clinical trials to be used in patient laboratory reports;

    - Evaluate scientific literature to develop therapeutic pathways and other physician education materials to be used by community oncologists and other healthcare professionals;

    - Work with KEW IT team to collaboratively develop and evolve content delivery platform.

    SKILLS AND ABILITIES REQUIRED:

    - PhD or MD with significant working experience in the human oncology field (4‐6 years) and thorough knowledge of mammalian signaling pathway, protein structures and interactions;

    - In depth knowledge of cancer genetics, cancer pathobiology and targeted therapies is required, background in clinical care delivery and/or clinical trials a plus;

    - Excellent oral and written communication skills, with the ability to communicate effectively to colleagues and staff across multi‐disciplinary areas.

    OTHER REQUIREMENTS:

    Provide a writing sample. Could be a research paper, grant application, analysis of a project or study. Please indicate your role in the writing samples (Author with PI, etc.) and be sure to redact any confidential information before submitting.

     

    KEW Group Inc. is committed to providing and promoting equal opportunities in our work environment. We support a workplace environment free from unlawful discrimination, and which enhances and celebrates the diversity of its workforce. KEW Group Inc. follows all federal and state laws as outlined and enforced under the United States Equal Opportunity Commission as well as the Massachusetts Commission against discrimination.


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    The Clinical Molecular laboratory of KEW seeks a highly motivated, full time, QC-QA Molecular Laboratory Technologist with quality standards and experience working in a CLIA environment.

    PRINCIPAL DUTIES AND RESPONSIBILITIES

    • Performs functional Quality Control testing for Molecular Diagnostic products and reagents, perform Quality Assessment analysis of Laboratory data; review data and summarize findings;
    • Completes all auxiliary laboratory support functions including Equipment calibration and maintenance as applicable
    • Responsible for following laboratory procedures and specimen processing, test performance, analyses, and reporting and maintaining records of patient test results as well as all safety and compliance regulations
    • Adheres to and documents the laboratory’s quality control procedures & policies, document all quality control activities, instrument and procedural calibrations and maintenance performed as well as troubleshooting
    • Be capable of identifying problems and exceptions that may adversely affect test performance or reporting of test results and document all corrective actions taken when test systems deviate from the laboratory's established performance specifications. 
    • Assist with Laboratory Process Improvement activities in support of overall lab improvement

    REQUIREMENTS/QUALIFICATIONS

    • Strong understanding of QC and QA within a CLIA/CAP laboratory setting
    • Bachelors’ of Science degree, plus experience in biological science or other related discipline required;  1-2+ years of Next-Generation Sequencing experience preferred
    • Experience in a clinical laboratory setting performing CLIA high complexity testing a plus
    • Strong knowledge of Microsoft Office programs and ability to learn new laboratory equipment and software packages to incorporate into daily laboratory processes.

    SKILLS AND ABILITIES REQUIRED

    • Familiar with molecular biology techniques and associated equipment including DNA extraction, RT-PCR, Next-Generation Sequencing and data interpretation preferred
    • Ability to work both in a team and independently
    • Flexibility and adaptability to a fast-paced and changing environment
    • Excellent organizational, time-management skills and highest attention to detail
    • Superior oral and written communication skills.

     


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    KEW Group is a personalized medicine company focused on providing oncologists access to the latest genomic insights to guide them in designing optimal, individualized treatment approaches for patients.
    KEW’s mission is to revolutionize cancer care by determining which treatments will work best for which patients and offering clinicians specific and practical, action-oriented solutions. KEW does this by coupling comprehensive patient-specific genomic data generated by their proprietary genomics-based
    CancerPlex® test together with expert-curated, evidence-based information about approved and emerging therapies. These results, including clinical trial and specific therapeutic recommendations, are then utilized by oncologists to guide treatment decisions and advance optimal patient care.

    THE ROLE
    KEW is seeking an exemplary bioinformatician to join our team as we develop a comprehensive knowledge base of cancer genomics and patient data. As the Lead Medical Bioinformatics Scientist, you will play a central role in creating capabilities to explore and exploit the clinical, laboratory, biological and pharmaceutical data that underlies KEW’s proprietary informatics pipeline. The ideal candidate will have broad expertise and be a pro-active, collaborative problem solver with a willingness to roll up their sleeves. This is a unique opportunity to be part of a fast growing company that is having significant
    impact on cancer patients and cancer care.


    PRINCIPAL DUTIES AND RESPONSIBILITIES:
    - Lead the development of a robust, scalable infrastructure to aggregate clinical, laboratory, biological, and pharmaceutical information and to utilize this information in the interpretation of laboratory data and generation of clinical reports;
    - Collaborate with clinical laboratory operations staff to ensure high quality, accurate, robust, scalable laboratory data analysis;
    - Collaborate with research and development team to identify opportunities to add functionality to clinical laboratory testing service, including identification and evaluation of new laboratory technologies;
    - Process, analyze and interpret high volumes of data as part of internal process performance studies;
    - Develop automated methods and software to support large-scale process performance analysis;
    - Prepare and deliver presentations based on scientific and technical progress/innovations.


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  • 10/30/15--23:57: Research Associate II
  • The Genetic Perturbation Platform (GPP) of the Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Research and Development team, directed by Dr. John G. Doench (www.broadinstitute.org/~jdoench). While we have had the map of the human genome for over a decade, the function of the information encoded by much of the genome remains obscure. Functional genomics attempts to understand the genome by perturbing the flow of information from DNA to RNA to protein, and continued technological development, first with RNAi and more recently with CRISPR, promises to decode the function of genes and enable us to understand how gene dysfunction leads to disease. The GPP, formerly known as the RNAi Platform, is a worldwide leader in functional annotation of the genome. We collaborate with researchers in many areas of biology, from infectious disease and stem cell biology to psychiatric disease and cancer, illustrating the incredible demand for continued innovation in functional genomics.

    The Broad Institute is a vibrant research environment with close links to top academic institutions and hospitals across the Boston area and provides the potential for contributions to be used and recognized worldwide. The people, the resources, and the culture of the Broad enable cross-cutting approaches to our most important biological problems and therapeutic challenges. The successful candidate will play a key role in developing and implementing technologies for functional genomics in mammalian cells, with a focus on CRISPR technology. She or he will design and perform bench-level experiments using molecular biology techniques and genetic manipulation of cell lines, working under the direct supervision of PhD-level staff scientists, and in time will transition to independent research projects. The successful candidate will have the opportunity to develop as a scientist and learn in a fast-paced and dynamic research environment at the cutting edge of biomedical research.

    KEY RESPONSIBILITIES
    - Work in close collaboration with Platform scientists to design, execute, and analyze experiments critical to the development and characterization of functional genomics technologies such as CRISPR- Present experimental rationale and results in group meetings- Attend meetings from other Platforms and Programs to learn about other science at the Broad- Shared maintenance and organization of the lab, i.e. rotating lab jobs

    QUALIFICATIONS
    - Bachelor’s degree in biology, chemistry, or a related field
    - 2-4 Years minimum experience necessary to effectively perform essential functions of the jobSKILLS
    - Standard molecular biology techniques, such as restriction digests, transformation, PCR, etc.
    - Mammalian cell culture.
    - Attention to detail in experimental execution and maintenance of a well-organized laboratory notebook.
    - Quantitative literacy with intermediate-to-advanced skill in Excel, R, or similar.
    - Ability to work flexible hours, as needed by research projects.
    - Self-motivated and curious experimentalist.
    - Supportive and respectful teammate.Not required, but desirable:
    - Lentiviral vector production, and infection.
    - Flow cytometry.
    - Basic programing in Perl, Python, or similar.

    ENVIRONMENTAL DEMANDS/CONDITIONS
    Infectious AgentsRecombinant DNAHuman/Animal Tissue/Fluids

    The Broad Institute will not offer visa sponsorship for this opportunity.

    EOE/Minorities/Females/Protected Veterans/Disabilities

    To apply for this position, please CLICK HERE


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  • 10/31/15--00:01: Research Associate I
  • The Genetic Perturbation Platform (GPP) of the Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Research and Development team, directed by Dr. John G. Doench (www.broadinstitute.org/~jdoench). While we have had the map of the human genome for over a decade, the function of the information encoded by much of the genome remains obscure. Functional genomics attempts to understand the genome by perturbing the flow of information from DNA to RNA to protein, and continued technological development, first with RNAi and more recently with CRISPR, promises to decode the function of genes and enable us to understand how gene dysfunction leads to disease. The GPP, formerly known as the RNAi Platform, is a worldwide leader in functional annotation of the genome. We collaborate with researchers in many areas of biology, from infectious disease and stem cell biology to psychiatric disease and cancer, illustrating the incredible demand for continued innovation in functional genomics.

    The Broad Institute is a vibrant research environment with close links to top academic institutions and hospitals across the Boston area and provides the potential for contributions to be used and recognized worldwide. The people, the resources, and the culture of the Broad enable cross-cutting approaches to our most important biological problems and therapeutic challenges. The successful candidate will play a key role in developing and implementing technologies for functional genomics in mammalian cells, with a focus on CRISPR technology. She or he will design and perform bench-level experiments using molecular biology techniques and genetic manipulation of cell lines, working under the direct supervision of PhD-level staff scientists, and in time will transition to independent research projects.

    The successful candidate will have the opportunity to develop as a scientist and learn in a fast-paced and dynamic research environment at the cutting edge of biomedical research. We encourage those about to complete or having recently completed their undergraduate study and are interested in gaining experience before continuing their education, although we are more interested in those whose timelines would allow for at least two years at the Broad. Depending on the availability of the right candidate, the start date of this position can be immediate or in the Spring / Summer of 2016.

    KEY RESPONSIBILITIES
    - Work in close collaboration with Platform scientists to design, execute, and analyze experiments critical to the development and characterization of functional genomics technologies such as CRISPR
    - Present experimental rationale and results in group meetings
    - Attend meetings from other Platforms and Programs to learn about other science at the Broad
    - Shared maintenance and organization of the lab, i.e. rotating lab jobs

    EDUCATIONRequired:
    - Bachelor’s degree in biology, chemistry, or a related field
    - 0-2 Minimum years’ experience necessary to effectively perform essential functions of the job.

    SKILLS
    - Attention to detail in experimental execution and maintenance of a well-organized laboratory notebook.
    - Quantitative literacy with intermediate-to-advanced skill in Excel, R, or similar.
    - Ability to work flexible hours, as needed by research projects.
    - Self-motivated and curious experimentalist.
    - Well-developed written and oral communication skills.
    - Supportive and respectful teammate.

    Not required, but desirable:
    - Standard molecular biology techniques, such as restriction digests, transformation, PCR, etc.
    - Mammalian cell culture.
    - Flow cytometry.
    - Lentiviral vector production and infection.

    ENVIRONMENTAL DEMANDS/CONDITIONS
    - Infectious AgentsRecombinant DNAHuman/Animal Tissue/Fluids

    The Broad Institute will not offer visa sponsorship for this opportunity.

    EOE/Minorities/Females/Protected Veterans/Disabilities

    To apply for this position, please CLICK HERE


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    KEW Group is a personalized medicine company focused on providing oncologists access to the latest genomic insights to guide them in designing optimal, individualized treatment approaches for patients.

    The Molecular Diagnostic laboratory of KEW Group seeks a highly motivated, full time, Specimen Processing Specialist with quality standards and experience working in a Lab environment.

    PRIMARY RESPONSIBILITIES AND ESSENTIAL DUTIES

    - Accessions and processes clinical specimens sent to laboratory for Clinical testing.

    - Utilizes a computer terminal to input, verify, and accurately match information provided on the client requisition with specimens submitted and correctly enters that data into LIMS system and Clinical Laboratory Standard Operating Procedures.

    - Logs all applicable information into accessory Lab systems and databases.

    - Identifies and properly handles discrepancies and/or missing information.

    - Works with Client Services to resolve patient and client issues.

    - Understands the complex relationship between test(s) ordered and specimen(s) received.

    - Coordinates with departments regarding all sample status updates and specimen shipping updates.

    - Documents all communication in the patient file and maintains appropriate records.

    - Triages calls and redirects them to a medical professional when highly technical and/or medical input is required.

    - Assists as needed to perform other related duties and special projects as required.

    Education, Skills, and Experience

    - High School diploma or equivalent required. Bachelors’ degree in Life Sciences is preferred.

    - Ability to decipher various forms of handwriting.

    - Ability to enter alpha and numeric information into the laboratory information system with required speed and accuracy as determined by the laboratory support supervisor.

    - Ability to communicate effectively and follow written and verbal instructions.

    - Excellent skills in English usage, grammar, punctuation, and spelling.

    - Excellent computer and data entry skills.

    - Extremely high level of accuracy and attention to detail.

    - Ability to multi‐task and work in a fast‐paced, deadline driven environment.

    - Ability to adapt to changing procedures, policies and work environment.


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  • 10/31/15--23:48: Clinical Veterinarian
  • BASIC SUMMARY: Clinical and preventative medical assessment and care of all laboratory species with participation in all procedures and policies related to animal care and husbandry in a GLP-compliant facility.

     

    ESSENTIAL DUTIES AND RESPONSIBILITIES:

    • Clinical and preventative medicine of all laboratory species including surgery if necessary
    • Involved in training of technical staff involved in handling of laboratory animals
    • Participation in IACUC process
    • Assist with oversight of controlled substance procurement and control
    • Consultation/collaboration with scientists/study directors
    • Participation in compliance with USDA and AAALAC regulations and guidelines
    • Assist with surgical model development and implementation
    • Assist with oversight of facility operations and maintenance
    • Perform all other related duties as assigned

    QUALIFICATIONS:

    • Education: D.V.M/V.M.D. degree or equivalent
    • Experience: Experience in a preclinical laboratory environment preferred
      • Minimum 1 yr experience in associated preclinical animal facility field
      • Certification/Licensure: ACLAM board certification or board eligible preferred, MA Veterinary Licensure, driver’s license

     

    PHYSICAL DEMANDS:
    Must be able to perform laboratory procedure that require talking, hearing, standing or sitting for long periods of time, entering data into an computer, using appropriate instruments, reaching with the hands and arms, working in narrow spaces, and wearing safety equipment (PPE) according to OSHA regulations and company standards

    WORK ENVIRONMENT:

    Research laboratory/medical environment, which requires use of sharp objects, working around mechanical parts, working with or near known or unknown toxic or caustic chemicals and biological hazards, exposure to fumes and airborne particles, working at a quiet to moderate noise levels

     

    COMMENTS:
    This position may require domestic travel, weekends and/or holidays.  Interested candidates should send a cover letter and CV to Dr. Misty Williams-Fritze at mwilliams@cbset.org

    All employees are required to satisfactorily perform the essential duties and responsibilities of their position. • Theessential duties and responsibilities listed above are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required. • Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this job. 


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