Are you the publisher? Claim or contact us about this channel


Embed this content in your HTML

Search

Report adult content:

click to rate:

Account: (login)

More Channels


Showcase


Channel Catalog


Channel Description:

Career postings for the Massachusetts Biotechnology Council

older | 1 | .... | 788 | 789 | (Page 790) | 791 | 792 | .... | 855 | newer

    0 0

    For more information, go to: http://www.cwsciences.com/Current-Openings/Sr-Research-Associate--Immunology

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


    0 0

    For more information, go to: http://www.cwsciences.com/Current-Openings/Associate-Scientist--Protein-Analytics

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


    0 0
  • 11/06/15--01:26: Quality Associate
  • Acorda Therapeutics is a leading pharmaceutical company, with a manufacturing facility in Chelsea MA. Acorda is looking for a Quality Associate  to oversee on-sight production  activities and support laboratory and / or quality investigations.  This individual will also perform related duties as assigned.

     *Essential Duties and Responsibilities include the following. Other duties may be assigned.

    • Oversight of production activities, including area clearance, review of batch records, and decisions on initiation of Discrepancies
    • Support of Laboratory and/or Quality Investigations
    • Oversight, review, and approval of Materials Management and Supply Chain activities
    • Supports project deadlines and ensures performance standards are met
    • Ensures compliance with all of Acorda policies and procedures including safety rules and regulations
    • Revision of SOPs, protocols, reports and master batch records for continuous improvement
    • Review and approval of Certificates of Analysis for Raw Materials, Intermediates, and Finished Goods
    • Provides basic support during compliance inspections conducted by external sources (i.e. health authorities)
    • Suggests resolution of compliance concerns to management
    • Maintains Quality databases and logs
    • Active member of a self-directed work team with operations personnel to critically evaluate and continuously improve manufacturing control systems

     Education and/or Experience:

    • Bachelor’s Degree in Physical Science or Chemistry preferred
    • Minimum of 3-5 years of experience in a GMP regulated environment.

     Qualifications:

    • Working knowledge of GMPs and their application to pharmaceutical manufacturing required
    •  Knowledge of FDA guidance documents required
    •  Knowledge of current FDA trends and use of FDA website tools required

     

    Other Skills and Abilities:

     Excellent oral and written communication skills

    Ability to work both independently and in a collaborative team setting

    Excellent organizational skills and attention to detail are required

    Demonstrates appropriate safety consciousness

    Physical Demands:

    The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

    •  Ability to stand for long periods of time
    • Ability to lift up to 40 lbs.
    • This position requires minimal travel; average travel for this position is

     

    *To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

     

    Please visit our website www.acorda.com/careers

     

    NO AGENCY PHONE CALLS PLEASE


    0 0
  • 11/06/15--01:28: Jr. Buyer
  • For more information, go to: http://www.cwsciences.com/Current-Openings/Jr-Buyer

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

     

    Commonwealth Sciences, Inc.

    www.cwsciences.com


    0 0

    Scientist – Preclinical Immunology

    Location: Cambridge, MA

     Kanyos Bio is searching for a Scientist in Immunology to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will design and execute pivotal proof of concept studies in pre-clinical models of autoimmunity, and assist in cross-functional development of our research strategy. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as expand our immunology expertise to enable successful IND filings.

     Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Design and execution of well-controlled in vivo and in vitro experiments
    • In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity, preferably in type-1 diabetes and/or celiac disease
    • Develop, execute, and trouble-shoot immunoassays, including in vitro cellular stimulations, flow cytometry, ELISA, and microscopy
    • Share and contribute scientific and technical know-how and experience with team members

     Qualifications:

    • Ph.D. in the domain of immunology, preferably with focus in autoimmunity, vaccines, or tolerance
    • 3-5 years of post-doctoral or biotech/pharma experience in developing and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in mouse models, primary immune cell characterization, immunoassay development, and protein chemistry
    • Proven track-record of scientific accomplishment and contributions to the field of autoimmunity research
    • Exceptional scientific reporting and documentation proficiency
    • She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KAS-01-2015-06)

     

    Applicants should be legally entitled for employment in the United States.

     Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale de Lausanne) in Switzerland with our sister company, Anokion.  Kanyos Bio and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos Bio aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist – Preclinical Immunology

     Location: Cambridge, MA

     

    Kanyos Bio is searching for a Scientist in Immunology to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will design and execute pivotal proof of concept studies in pre-clinical models of autoimmunity, and assist in cross-functional development of our research strategy. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as expand our immunology expertise to enable successful IND filings.

    Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Design and execution of well-controlled in vivo and in vitro experiments
    • In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity, preferably in type-1 diabetes and/or celiac disease
    • Develop, execute, and trouble-shoot immunoassays, including in vitro cellular stimulations, flow cytometry, ELISA, and microscopy
    • Share and contribute scientific and technical know-how and experience with team members

     Qualifications:

    • Ph.D. in the domain of immunology, preferably with focus in autoimmunity, vaccines, or tolerance
    • 3-5 years of post-doctoral or biotech/pharma experience in developing and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in mouse models, primary immune cell characterization, immunoassay development, and protein chemistry
    • Proven track-record of scientific accomplishment and contributions to the field of autoimmunity research
    • Exceptional scientific reporting and documentation proficiency
    • She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KAS-01-2015-06)

    Applicants should be legally entitled for employment in the United States.

    Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale de Lausanne) in Switzerland with our sister company, Anokion.  Kanyos Bio and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos Bio aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist – Preclinical Immunology

     Location: Cambridge, MA

     Kanyos Bio is searching for a Scientist in Immunology to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will design and execute pivotal proof of concept studies in pre-clinical models of autoimmunity, and assist in cross-functional development of our research strategy. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as expand our immunology expertise to enable successful IND filings.

      Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Design and execution of well-controlled in vivo and in vitro experiments
    • In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity, preferably in type-1 diabetes and/or celiac disease
    • Develop, execute, and trouble-shoot immunoassays, including in vitro cellular stimulations, flow cytometry, ELISA, and microscopy
    • Share and contribute scientific and technical know-how and experience with team members

    Qualifications:

    • Ph.D. in the domain of immunology, preferably with focus in autoimmunity, vaccines, or tolerance
    • 3-5 years of post-doctoral or biotech/pharma experience in developing and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in mouse models, primary immune cell characterization, immunoassay development, and protein chemistry
    • Proven track-record of scientific accomplishment and contributions to the field of autoimmunity research
    • Exceptional scientific reporting and documentation proficiency
    • She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KAS-01-2015-06)

     Applicants should be legally entitled for employment in the United States.

     Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale de Lausanne) in Switzerland with our sister company, Anokion.  Kanyos Bio and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos Bio aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist – Preclinical Immunology

     Location: Cambridge, MA

     Kanyos Bio is searching for a Scientist in Immunology to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will design and execute pivotal proof of concept studies in pre-clinical models of autoimmunity, and assist in cross-functional development of our research strategy. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as expand our immunology expertise to enable successful IND filings.

      Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Design and execution of well-controlled in vivo and in vitro experiments
    • In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity, preferably in type-1 diabetes and/or celiac disease
    • Develop, execute, and trouble-shoot immunoassays, including in vitro cellular stimulations, flow cytometry, ELISA, and microscopy
    • Share and contribute scientific and technical know-how and experience with team members

     Qualifications:

    • Ph.D. in the domain of immunology, preferably with focus in autoimmunity, vaccines, or tolerance
    • 3-5 years of post-doctoral or biotech/pharma experience in developing and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in mouse models, primary immune cell characterization, immunoassay development, and protein chemistry
    • Proven track-record of scientific accomplishment and contributions to the field of autoimmunity research
    • Exceptional scientific reporting and documentation proficiency
    • She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KAS-01-2015-06)

     Applicants should be legally entitled for employment in the United States.

     Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale de Lausanne) in Switzerland with our sister company, Anokion.  Kanyos Bio and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos Bio aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist, Antibody Discovery & Optimization

    Location: Cambridge, MA

     

    Kanyos Bio is searching for a  Scientist  to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will formulate and execute a proprietary antibody and protein engineering platform. Assist in cross functional development of research and development strategy, plan and coordinate the resources for the protein engineering function. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as building out an protein engineering function from scratch and developing unique proteins to enable successful IND filings.

     

    Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Antibody display and screening, including affinity maturation
    • Conceive and execute protein stability, biochemical activity, and antibody affinity assays
    • Rational protein/enzyme design
    • Development of humanization strategy and backbone selection
    • Develop a variety of expression systems (E.coli, mammalian, yeast)
    • Share and contribute technical know-how and experience with team members

     

    Qualifications:

    • Ph.D. in the domain of protein/antibody engineering, biochemistry
    • 5+ years of post-doctoral or biotech/pharma experience in conceiving and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in molecular biology, antibody library design, construction, and screening, as well as protein chemistry and design
    • Exceptional scientific reporting and documentation proficiency

     

    She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     

    Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KSC-01-2015-06)

     

    Applicants should be legally entitled for employment in the United States.

     

    About Kanyos Bio:

    Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale Lausanne) in Switzerland with our sister company, Anokion.  Kanyos and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist, Antibody Discovery & Optimization

    Location: Cambridge, MA

     

    Kanyos Bio is searching for a  Scientist  to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will formulate and execute a proprietary antibody and protein engineering platform. Assist in cross functional development of research and development strategy, plan and coordinate the resources for the protein engineering function. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as building out an protein engineering function from scratch and developing unique proteins to enable successful IND filings.

     

    Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Antibody display and screening, including affinity maturation
    • Conceive and execute protein stability, biochemical activity, and antibody affinity assays
    • Rational protein/enzyme design
    • Development of humanization strategy and backbone selection
    • Develop a variety of expression systems (E.coli, mammalian, yeast)
    • Share and contribute technical know-how and experience with team members

     

    Qualifications:

    • Ph.D. in the domain of protein/antibody engineering, biochemistry
    • 5+ years of post-doctoral or biotech/pharma experience in conceiving and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in molecular biology, antibody library design, construction, and screening, as well as protein chemistry and design
    • Exceptional scientific reporting and documentation proficiency

     

    She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     

    Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KSC-01-2015-06)

     

    Applicants should be legally entitled for employment in the United States.

     

    About Kanyos Bio:

    Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale Lausanne) in Switzerland with our sister company, Anokion.  Kanyos and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist, Antibody Discovery & Optimization

    Location: Cambridge, MA

     

    Kanyos Bio is searching for a  Scientist  to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will formulate and execute a proprietary antibody and protein engineering platform. Assist in cross functional development of research and development strategy, plan and coordinate the resources for the protein engineering function. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as building out an protein engineering function from scratch and developing unique proteins to enable successful IND filings.

     

    Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Antibody display and screening, including affinity maturation
    • Conceive and execute protein stability, biochemical activity, and antibody affinity assays
    • Rational protein/enzyme design
    • Development of humanization strategy and backbone selection
    • Develop a variety of expression systems (E.coli, mammalian, yeast)
    • Share and contribute technical know-how and experience with team members

     

    Qualifications:

    • Ph.D. in the domain of protein/antibody engineering, biochemistry
    • 5+ years of post-doctoral or biotech/pharma experience in conceiving and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in molecular biology, antibody library design, construction, and screening, as well as protein chemistry and design
    • Exceptional scientific reporting and documentation proficiency

     

    She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     

    Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KSC-01-2015-06)

     

    Applicants should be legally entitled for employment in the United States.

     

    About Kanyos Bio:

    Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale Lausanne) in Switzerland with our sister company, Anokion.  Kanyos and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Scientist, Antibody Discovery & Optimization

    Location: Cambridge, MA

     

    Kanyos Bio is searching for a  Scientist  to provide expertise in developing our immunotechnology for targeted therapies for type-1 diabetes and celiac disease.  This individual will formulate and execute a proprietary antibody and protein engineering platform. Assist in cross functional development of research and development strategy, plan and coordinate the resources for the protein engineering function. The individual will gain a unique experience working with colleagues in Europe and Asia, as well as building out an protein engineering function from scratch and developing unique proteins to enable successful IND filings.

     

    Responsibilities:

    The successful candidate will advance several aspects of Kanyos Bio’s lead molecules to support pre-clinical investigations, using their targeted skill set to accomplish the following responsibilities:

    • Antibody display and screening, including affinity maturation
    • Conceive and execute protein stability, biochemical activity, and antibody affinity assays
    • Rational protein/enzyme design
    • Development of humanization strategy and backbone selection
    • Develop a variety of expression systems (E.coli, mammalian, yeast)
    • Share and contribute technical know-how and experience with team members

     

    Qualifications:

    • Ph.D. in the domain of protein/antibody engineering, biochemistry
    • 5+ years of post-doctoral or biotech/pharma experience in conceiving and conducting laboratory research
    • In-depth knowledge and extensive hands-on experience in molecular biology, antibody library design, construction, and screening, as well as protein chemistry and design
    • Exceptional scientific reporting and documentation proficiency

     

    She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.

     

    Contact:

    To apply, please send your cover letter and resume to: careers@kanyos.com (Job Reference KSC-01-2015-06)

     

    Applicants should be legally entitled for employment in the United States.

     

    About Kanyos Bio:

    Kanyos Bio is an early-stage immunotechnology company focused on developing targeted therapies for type-1 diabetes and celiac disease. Our technology originated at EPFL (Ecole Polytechnique Fédérale Lausanne) in Switzerland with our sister company, Anokion.  Kanyos and Anokion are collaborating in this effort with Astellas Pharma.  As an independent affiliate, Kanyos aims to develop antigen-specific, disease-modifying therapies for patients with type-1 diabetes and celiac disease by leveraging the immunotechnology expertise of Anokion and the clinical translation experience of Astellas.


    0 0

    Position Summary
    Moderna is seeking a cGMP Pilot Plant Senior Manufacturing Associate for a second shift position based at their Cambridge, MA site. The individual in this role will be capable of working with and leading a cohesive team responsible for producing high quality mRNA-based medicines for evaluation in human clinical trials. He/she will apply their demonstrated knowledge of common bioprocess unit operations and cGMPs to enable technical success with stringent adherence to a Quality System that respects global regulatory expectations. The successful candidate will be a critical thinker that can assess issues and act quickly and appropriately to effect short-term remediation and long-term solutions. They will have strong observational and documentation skills and will communicate their technical and operational observations as cross-functional ambassadors of the Pilot Plant group to Quality Control, Quality Assurance, Logistical and Process Development Technology Transfer counterparts Second shift hours are 3:00 - 11:00 pm.

    Responsibilities
    * Be a leadership figure on an evening or overnight shift, with strong accountability for the productivity and integrity of the output of that team.
    * Demonstrate general knowledge of standard laboratory practices and equipment.
    * Demonstrate an understanding of GMPs uphold the highest GMP standards for their team.
    * Establish and follow written procedures for the clear and accurate documentation of equipment operation and process instructions, and of process data.
    * Be an authority figure that can train others on specific process operations as well as GMP principles.
    * Monitor process operations to ensure compliance with specifications.
    * Complete tasks in support of large scale manufacturing, including in the care of high-value capital equipment, such as pilot-scale chromatography systems.
    * Take a leadership role in the investigation of procedural deviations.
    * Be capable of assuming Batch Leader responsibilities that span all shifts and all unit operations, including the aggregation of in-process control, process parameter and quality attribute data for both Drug Substance and Drug Product processes, and accountability for batch documentation closeout with Quality Assurance counterparts.
    * Coordinate closely with Warehousing personnel to assure seamless supply of raw materials and consumables from inventory.
    * Coordinate with Facilities personnel on equipment and facility maintenance issues.
    * Practice safe work habits and adhere to Moderna's safety procedures and guidelines.
    * Utilize knowledge to improve operational efficiency.
    * Adhere to Pilot Plant gowning procedures and maintain a clean general operating area.
    * Adhere to documented waste handling procedures to respect environmental regulations.

    Minimum Qualifications
    * Bachelor's degree in Biology, Biochemistry, Molecular Biology, Chemistry or Chemical Engineering
    * 3-5 years of cGMP operational experience in a biotech or pharmaceutical early or late-phase manufacturing facility.
    * Experience with major pilot-scale chromatography, TFF and single-use equipment platforms.

    Preferred Qualifications
    * Master's degree in Biology, Biochemistry, Molecular Biology, Chemistry or Chemical Engineering
    * 5+ years of professional/industrial cGMP experience in a biotech, diagnostic, therapeutic or pharma company
    * A demonstrated history of defining and implementing CAPA's in response to deviations.
    * Experience with major pilot-scale chromatography, TFF and single-use equipment platforms.

    Competencies
    * Aligning Performance for Success
    * Coaching
    * Decision Making
    * Detail Oriented
    * Developing Others
    * Energy
    * Facilitating Change
    * Planning and Organizing
    * Safety Awareness
    * Stress Tolerance
    * Technical / Professional Knowledge
    * Technical Transfer

    Why Join Moderna
    Moderna is pioneering messenger RNA Therapeutics™, an entirely new in vivo drug modality that produces human proteins or antibodies inside patient cells, which are in turn secreted or active intracellularly. This breakthrough platform addresses currently undruggable targets and offers a superior alternative to existing drug modalities for a wide range of disease conditions. Moderna has developed a broad intellectual property estate, including more than 250 patent applications covering novel nucleotide chemistries and drug compositions. The company plans to develop and commercialize its innovative mRNA drugs through a combination of strategic relationships as well as newly formed ventures.

    Founded in late 2010 by Flagship VentureLabs, Cambridge-based Moderna is privately held and currently has strategic agreements with AstraZeneca and Alexion Pharmaceuticals.

    Moderna recently signed a collaboration agreement with Astra Zeneca that provided a $240MM upfront payment (plus milestone payments).

    Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

    Application URL:http://www.aplitrak.com/?adid=YWxsaXNvbi5tYXllci4yNDg1OS4zMTY3QG1vZGVybmF0aGVyYXBldXRpY3NpbmMuYXBsaXRyYWsuY29t


    0 0

    Primary Role:
    This position is accountable for development, implementation, and maintenance of GMP related training programs in support of manufacturing operations. Other duties include facilitating Instructor Led Training and partnering with business process owners to developing and executing training and change management strategies.

    Responsibilities:
    * 40% Developing Training Materials
    * 30% Delivery of Training
    * 20% Training Project Management
    * 10% Supporting Quality Systems and Inspections

    Education & Experience Requirements:
    * BS/BA degree or equivalent
    * 5+ years related experience

    Key Skills, Abilities, and Competencies:
    * With general supervision develop training materials for manufacturing operations
    * Partner with Business Process Owners to determine training assignment and delivery approach for new and revised documents
    * Develop and maintain curricula for manufacturing personnel
    * Facilitate Instructor Led Trainings, including new hire and gowning
    * Serve as manufacturing learning consultant to assess needs and develop solutions to address performance issues and expand organizational competencies to enable business goals
    * Partner with HSE to lead initiatives that result in an effective culture of safety
    * Conduct periodic reviews of training systems to maintain compliance with corporate training policies and procedures
    * Serve as a Subject Matter Expert for manufacturing training programs during regulatory agency inspections
    * Review training content for instructional design and content accuracy
    * Serve as a master instructor, exemplifying excellent presentation and classroom facilitation skills
    * Integrate new tools, methods and industry best practices into training program. Champion and infuse new ideas and behaviors into the training team.
    * Project manage training improvement initiatives
    * Support training programs and related change management efforts
    * Excellent communication, interpersonal and professional competencies
    * Focus on results
    * Program management, influencing and negotiation
    * Presentation and classroom facilitation
    * Collaborative style and customer focus
    * Comprehensive knowledge of global cGMP requirements and ICH Guidelines
    * An understanding and ability to apply adult learning principles and instructional design principles and methodology
    * Multi-task and lead cross-functional projects

    Complexity and Problem Solving:
    * High degree of autonomy and self-directed activities prioritized according to business need. Excellent critical thinking / problem solving skills.

    Internal and External Contacts:
    * Internal: Technical Operations Training Community
    * Vendor: As necessary
    * Customer: Manufacturing Operators and Management
    * Other: Quality Organization, IT, HSE
    * Other: Cross Functional Colleagues as required

    Shire's Brave culture offers employees with diverse backgrounds the opportunity to enable those with life altering conditions to lead better lives. Shire is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by applicable law. US Applicants who require accommodation in the job application process may contact 484-595-8400.

    Application URL:http://www.aplitrak.com/?adid=bGF1cmVuZC40MzQ2Mi4zMTY3QHNoaXJlLmFwbGl0cmFrLmNvbQ


    0 0

    The Senior Project Manager will be responsible for the integration, creation and execution of multiple complex CMC & Preclinical development plans. By partnering closely with Project Leaders and cross-functional Project Team members, the Senior Project Manager develops and maintains fully integrated project plans to ensure that deliverables are successfully executed, are in accordance with project and disease area objectives, and are within budget. The Senior Project Manager is also responsible for comprehensive communication, including status reporting, risk management and escalation of issues to cross-functional stakeholders and Senior Management.

     

    KEY RESPONSIBILITIES:

     

    Advance those of the CMC & Preclinical  Project Manager to include the following additions or refinements:

     

    • Independently leads sub-teams for critical development projects
    • Strategically develops plans, goals, and logistics for projects, gaining cooperation and consensus
    • Regularly interacts with functional areas beyond CMC & Preclinical (CP), such as Regulatory and/or Clinical
    • Acts as a liaison for external suppliers
    • Conduct scenario planning to proactively provide analysis and recommendations on alternative development plans, along with the associated assumptions and risks
    • Effectively summarize key information such as program progress, timeline updates, and risk/opportunity assessments for periodic presentations to management
    • Proactively provides key project issues and status to senior management to ensure alignment 
    • Compile succinct reports and prepare minutes for select internal meetings. Methodically track all action items, and find innovative ways to stay abreast of this multi-dimensional task
    • Maintain frequent communication with the network of cross-functional internal and external stakeholders so that all parties are aware of current program status, issues, contingencies, and milestones
    • Contribute to the best practices of project management to support the continued success and evolution of the department

     

    PROJECT MANAGEMENT AND COMMUNICATIVE SKILLS:

     

    In addition to the attributes of a CMC & Preclinical  Project Manager:

     

    • Has maintained excellence in all expected role obligations and responsibilities
    • Distinction achieved by mentoring subordinates, maintaining procedural and ethical standards and cultivating healthy team morale
    • Superior communicator (verbal and written) within all levels of the department and cross functionally throughout the organization
    • Demonstrates outstanding determination and/or persistence in supporting projects

     

    PREFERRED EDUCATION AND EXPERIENCE:

     

    • B.S./M.S./Ph.D. with 8+years of relevant development or project management work experience

     


    0 0
  • 11/08/15--07:33: Project Manager
  • PROMETRIKA, LLC provides a challenging and dynamic environment that encourages learning and collaboration. We are looking for a high-energy, bright-minded individual who is skilled at managing project activities and performing other services across functional areas of the business.

     PROJECT MANAGEMENT:

     Oversee multiple projects simultaneously.

     Coordinate project organization, implementation and management activities between all functional areas at PROMETRIKA and with the client using PROMETRIKA’s Project Manual, procedures and tools.

     Prepare the project plan including timelines and resource requirements using these tools to measure actual project progress.

     Work with PROMETRIKA study teams and clients to implement solutions to challenges related to timelines, schedules, resources, budgets, etc.

     Along with internal finance project management, develop, evaluate and manage project budgets against project milestones for assigned projects.

     Track and report significant changes in scope of work and recommend change of scope orders to management, when appropriate.

    Coordinate project team meetings (prepare agenda and meeting minutes) for assigned projects if stated in the contract. 

    Prepare project status reports of assigned projects for the client as required. 

    Participate in all formal interactions with the client on a pre-determined frequency. 

    Coordinate monthly Project Finance Review meetings with executive management for all impacted projects at PROMETRIKA. Coordination includes preparing agenda’s, preparing minutes, and assisting other Project Managers prepare the necessary reports, as needed. 

    Participate in the maintenance of the Project Manual and SOPs related to Project Management. 

    Participate in customizing established tools for finance project management for project managers. 

    Perform other duties as assigned.

    SUPPORTING OTHER FUNCTIONAL GROUPS:

     Examples of the types of tasks in other functional areas: 

    Coordination, attendance and preparation of meeting minutes across functions. 

    Clinical Operations – support the team as needed to meet project goals and timelines 

    Medical Writing - prepare or QC documents including study design and protocol development 

    Biostatistics - participate in meetings, prepare minutes, and interactions with study physicians 

    Client Relations - assisting with Account Management tasks and budget preparation 

    EDUCATION/EXPERIENCE: 

    • Minimum of a Bachelor’s degree in a scientific discipline.  An advance degree preferable.
    • Minimum of three years of project management experience, preferably within the pharmaceutical or biotechnology industry. 
    • At least five years of project management experience within an academic environment will also quality for this role.

     REQUISITE SKILLS: 

    Excellent written and oral communication skills. 

    Excellent organizational skills with ability to multi-task. 

    Demonstrated ability to effectively manage projects with limited supervision. 

    Demonstrated ability to accurately identify and resolve problems. 

    Demonstrated ability to work effectively with representatives from a broad range of scientific disciplines. 

    Solid understanding of the drug development process. 

    Demonstrated expertise with PCs and standard Microsoft Office software applications. 

    Familiarity with formal concepts of project management and planning. 

    PROMETRIKA, LLC is conveniently accessible by public transportation. Compensation and benefits are highly competitive including comprehensive health, dental, disability and life insurance plans, and 401(k). Qualified candidates please email resume to our managing human resources representative.

     


    0 0

    Job ID: 26547
    Date Posted: 05/29/2015
    Location: Building HM
    Job Family: Technician/Technologist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Job Description

    The Wong laboratory is focused on understanding the genetic alterations involved in lung cancer initiation and progression through the use of human lung cancer cell lines and genetically engineered mouse lung cancer models. Equally important, we are employing these different model systems for the testing of novel therapeutics that would be effective in the treatment of genetically stratified lung cancers.

    • The successful candidate for this position will be energetic, eager to learn new techniques, and excited by the opportunity to work in a supportive and collegial multidisciplinary lab environment.
    • Additional requirements for this position include strong interpersonal and organizational skills that are conducive to effective communication and contribute to a congenial work environment. Maintain positive work atmosphere by behaving and communicating in a professional manner. Attention to detail, methodical record keeping, and a desire to contribute to research projects both independently and within a team.

    Primary duties include:

    • Assist in the maintenance, care and drug administration of large mouse colonies (PO, IP, gavage, etc). This includes breeding and weaning of multiple genetic strains of mice and PCR-based genotyping of mice.
    • Assist with and perform necropsies; tissue collection
    • Daily health checks
    • Adhere to SOPs and animal protocols

    Minimum qualifications:

    BS in biological sciences. Also require hands-on experience, laboratory research, and basic computer skills. Demonstrated experience in animal handling/dosing preferred.



    Schedule

    Regular Monday - Friday schedule. Some flexibility required dependent on on-going experiments.

    Weekly paid employee.



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.




    Apply Here

    PI92264404


    0 0
  • 11/08/15--02:37: Research Technician
  • Job ID: 27314
    Date Posted: 11/05/2015
    Location: Smith Building
    Job Family: Technician/Technologist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.

    The Center for Cancer Systems Biology (CCSB) in the Department of Cancer Biology has an immediate opening for a Research Technician with a Bachelor's or Master's degree to join the CCSB Edgotyping Project.

    The major duties are to work with CCSB Group Leaders and Scientists to carry out ORF cloning, high throughput binary interaction screening, microbial transformations and mammalian cell transfections, and computational analysis of networks usingMySQL and Cytoscape as part of a large-scale protein interaction mapping project to investigate network perturbations arising from genetic variation in familial disorders such as Retinitis Pigmentosa and Usher Syndrome.

    Responsibilities will involve all steps of protein interaction mapping using yeast two hybrid systems and mammalian cell culture, including preparation of media, performing primary screening assays, carrying out validation assays employing various cell-based assay systems, maintaining strains and microbial stocks, along with integration of data from external data sources and implementation via use of programming languages including R, C and Python and data visualization using Cytoscape. The hours of this position will vary to meet deadlines in order to complete experiments and achieve project goals in a timely fashion.

    Prior experience working in a laboratory or on an internship in a laboratory setting is required. Direct hands-on experience with one or more experimental techniques (such as use of liquid handling robots, colony PCR, site-directed mutagenesis, high throughput Gateway recombinational cloning, plasmid vector development, preparation of microbial media, bacterial and yeast transformation, mammalian cell culture and yeast two-hybrid screening) is required, plus hands-on experience in data integration/analysis/visualization involving acquisition of genetic information from public repositories along with demonstrated ability to implement various statistical and network analyzes using the program R and produce visual outputs of network datasets is preferred.



    Schedule

    This is a full time position only with variable hours.



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.




    Apply Here

    PI92265658


    0 0
  • 11/08/15--02:39: Lab Supervisor
  • Job ID: 27313
    Date Posted: 11/04/2015
    Location: Dana
    Job Family: Laboratory/Research
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    POSITION SUMMARY:

    The responsibilities of this position will include, but not be limited to, oversight and management of two research laboratories in the Molecular and Cellular Oncology (MCO) division. This includes the management of daily laboratory operations, ensuring adequate resources to perform the research activities, and following of all compliance and institute policy regarding laboratory operations. The individual would be current in technologies used in the lab, participate in improving operations of the lab, both administratively and scientifically, recommend and implement changes including new reagents, consumables, instrumentation and database-type solutions to track key experimental data and assets. This individual will have training and supervisory duties.

    PRIMARY DUTIES AND RESPONSIBILITIES:

    • Coordinate two major lab operations within MCO
    • Responsible for ensuring compliance in the laboratory (ex. scheduling lab safety training, etc.)
    • Coordination of on-boarding activities for new research technicians and fellows
    • Scientific and technical contributions to various lab projects, including the research work on those experiments responsible; designing and executing advanced experiments, setting strategy, and analysis of results
    • Collaborate with the investigators to assess short and long-range needs regarding research technologies and facilities
    • Work with the investigators on reviewing and updating standard operating procedures in the laboratory
    • Provide input on equipment purchases
    • Ensure appropriate and timely equipment services including calibration, maintenance, repairs, service contract renewal, software and hardware upgrades and validation activities
    • Support the investigators to ensure the efficient and cost-effective management of the laboratories
    • Professional development to provide intellectual and interactive commitment to the position by keeping up with appropriate literature and research publications, as well as attending seminars, etc.
    • Financial management responsibilities – oversight of laboratory supply purchases
    • Attend applicable meetings as the laboratory representative
    • Supervisory and training responsibilities
    • Project management

    JOB QUALIFICATIONS:

    Bachelors Degree required. At least 5 years lab operations experience required.

    • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff
    • Ability to analyze information and use logic to address work-related issues and problems.
    • Must have attention to detail and be thorough in completing work tasks
    • Ability to work within a team environment



    Schedule

    Monday - Friday schedule, though there may be some flexibility required dependent on on-going experiments and operations.

    Weekly paid position.



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.




    Apply Here

    PI92266281


    0 0
  • 11/08/15--05:01: Head of CMC
  • If interested and qualified, please include Req # 2015-012 in the subject line when emailing resume tocareers@InotekPharma.com.

    Position Summary

    This person will be responsible for Chemistry, Manufacturing and Controls (CMC) for the Company’s pharmaceutical assets.  The successful candidate will create and implement comprehensive CMC strategies, plans and processes to support all phases of pharmaceutical development (from pre-IND, through clinical development and up to commercial manufacturing scale).   The new Head of CMC will partner closely with internal and external stakeholders and work collaboratively across multiple functional areas.  S/he will have strong working relationships with outsourcing partners and internal colleagues.

    Responsibilities

    • Develop and execute CMC strategy for the Active Pharmaceutical Ingredient (API) process development and manufacturing, and Drug Product (DP) formulation, manufacturing and testing for non-clinical and clinical development and ultimately commercial sale
    • Identify, qualify, contract and manage contract formulation and manufacturing partners for GMP production of API and DP
    • Responsible for managing technical transfer between CRO’s or development partners producing API or DP
    • Drafting, review and approve technical CMC documentation including but not limited to stability protocols and reports, deviation reports, technology transfer protocols, validation protocols, technical reports, manufacturing and labeling procedures, etc., to ensure conformance with GMP regulations and quality agreements with vendors
    • Work closely with Clinical Operations and Quality Assurance to insure adequate supply of DP required to execute clinical development plans
    • Develop and manage inventory of API and non-GMP DP for use in non-clinical pharmacokinetic, pharmacology and animal safety studies
    • Maintain compliance with all regulatory guidance and company requirements
    • Responsible for analytical test method development and validation, and for the collection and interpretation of initial and stability testing data, directly, or through the management of a CRO partner
    • Prepare all CMC-related regulatory submissions, including INDs, NDAs and CTAs
    • Attend FDA meetings and teleconferences to address any CMC-related questions, comments or issues
    • Organization and documentation of regular CMC program reviews, and the preparation of communications on CMC issues for Inotek Management and Board of Directors

    Minimum Qualifications

    • BS degree in the life sciences (i.e., Chemistry, Chemical Engineering, Pharmaceutics, Pharmaceutical Sciences or closely related field)
    • 10 or more years of drug development experience in CMC
    • Prior experience technical development and supportive regulatory requirements in all functions of Pharmaceutical development (process chemistry, analytical methods, formulations, supply chain etc.)
    • Detailed knowledge and understanding of GMP, USP and ICH guidance and regulations
    • Working knowledge CMC development strategies across IND-NDA stages
    • Strong organizational skills and demonstrated expertise in the management of a team of CMC consultants and vendors
    • Proven ability to identify/understand/solve problems, anticipate and communicate risk
    • Past experience developing and executing risk-management plans for CMC development programs
    • Excellent written/oral communication skills with cross-functional effectiveness
    • Demonstrated ability to work collaboratively within team structure to accomplish mission critical corporate objectives
    • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the education and experience listed above

    Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)

    • PhD in Chemistry, Pharmaceutical Sciences, Chemical Engineering, Pharmaceutics or related field.
    • 15+ years of relevant experience in the life sciences
    • Prior success interacting with chemistry reviewers at regulatory authorities
    • Previous experience drafting CMC-related sections of IND submissions and NDA applications
    • Successful track record in a small pharma/biotechnology work environment

    Competencies

    • Adaptability / Perseverance– The ability to adapt to working effectively within a variety of situations; adapts enthusiastically to organizational change and to changes in job demands.  Shows initiative and demonstrates learning orientation and flexibility. Pursues tasks with energy, drive and enthusiasm, even in the face of adversity.
    • Communication and Teamwork– The ability to effectively express ideas in written, visual, and oral context.  The ability to work co-operatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.
    • Creativity/Innovation - creating a boundary-less environment that fosters curiosity and taking risks, openness to new approaches, diversity of new thought, blank page creativity and opportunistic thinking.
    • Job Knowledge– Achieves and maintains technical and professional proficiency related to current job position and areas of expertise.
    • Passion - create an exciting environment where there is the passion of academia with the discipline of industry where there is true intellectual exchange and ideas are challenged effectively.
    • Results Orientation / Productive Work Habits– Drives issues to closure and gets the job done.  Skilled at analyzing scope of work, as well as planning and executing a successful outcome.  Understands and assigns / utilizes resources effectively and efficiently.

    If interested and qualified, please include Req # 2015-012 in the subject line when emailing resume tocareers@InotekPharma.com.

    Company Overview

    Inotek Pharmaceuticals is a clinical-stage, publicly traded, biopharmaceutical company focused on the discovery, development and commercialization of novel therapies to treat glaucoma and other serious diseases of the eye. Our common stock is listed on the NASDAQ Global Market under the symbol "ITEK."

    Glaucoma is a disease of the eye that is typically characterized by structural evidence of optic nerve damage, vision loss and consistently elevated intraocular pressure, or IOP. Our lead product candidate, trabodenoson, is a first-in-class selective adenosine mimetic.

    This molecule was developed to selectively stimulate a specific adenosine subreceptor, and was developed initially to prevent apoptosis following ischemia-reperfusion injuries such as stroke or myocardial infarction. In the eye, stimulation of this same receptor has the effect of augmenting the intrinsic function of the eye's trabecular meshwork, or TM, which is the main passageway for transporting the aqueous humor, a liquid that maintains the eye's shape and typically experiences elevated pressure in glaucoma. We believe that by enhancing this naturally occurring TM process, rather than changing the fundamental dynamics of pressure regulation in the eye, trabodenoson's mechanism of action should result in a lower risk of unintended side effects and long term safety or tolerability issues. Additionally, trabodenoson's unique mechanism of action in the TM should complement the activity of existing products that lower IOP by addressing different parts of the in-flow and out-flow system of the eye.

    Trabodenoson has completed Phase 2 clinical development in primary open-angle glaucoma (POAG) and ocular hypertensive (OHT) patients and is ready for Phase 3. Trabodenoson, if ultimately approved by regulatory agencies, will be a valuable, innovative product that ophthalmologists can use alone or in combination with other approved medicines for glaucoma, and would also be a new treatment option for those patients who are refractory to current drug therapies.

    The neuroprotective potential of trabodenoson is supported by the basic biology of adenosine, which has shown that stimulation of the A1 receptor by endogenous adenosine protects tissues of the central nervous system. A pre-clinical study of the impact of high IOP on retinal ganglion cells showed that trabodenoson could protect this key population of cells in the retina that, when lost, results in the irreversible vision loss. A preclinical program investigating a number of currently untreatable degenerative retinal diseases that would benefit from the neuroprotective action of trabodenoson is ongoing with the goal of supporting proof-of-concept clinical trials.

    Inotek, in addition to having built a potential first-in-class ophthalmic product candidate in trabodenoson, has an experienced management team with a track record of multiple successful NDA approvals and successful product launches. Inotek intends to advance its programs through regulatory approval and to market its ophthalmology products, a specialty area, with a relatively small and focused sales and marketing team. The Company is based in Lexington, MA.

    For more information, please visit www.InotekPharma.com

    If interested and qualified, please include Req # 2015-012 in the subject line when emailing resume tocareers@InotekPharma.com.

    Inotek Pharmaceuticals Corporation is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.

     


older | 1 | .... | 788 | 789 | (Page 790) | 791 | 792 | .... | 855 | newer