Compass Therapeutics is an antibody discovery and development company focused on comprehensively drugging the tumor-immune synapse with combinations of human monoclonal antibodies, multiclonals and engineered protein constructs. Compass is industrializing antibody discovery and decentralizing biologic validation through a partnership-first mentality that leverages best-in-class technologies and top-tier academic laboratories around the world. Novel scientific insights are validated and explored deeply inside our labs before Compass pursues the best proprietary combinations of therapeutics into human clinical trials.
In 2015, Compass quietly closed a $120mm Series A financing to fund our ambitious plan to build a fully-integrated biopharmaceutical company from the ground up. Our investors are among the most sophisticated venture capitalists in the industry who exemplify our philosophy of building long term economic value only by delivering therapeutics with meaningful efficacy beyond standard of care. They include OrbiMed Advisors, Fidelity Biosciences, Borealis Ventures, Google Ventures and a handful of smaller VCs and passionate angel investors.
Our Protein Analytics Group is seeking a Senior Associate Scientist at our Cambridge, MA site.
Principal Responsibilities:
- Perform analytical characterization of antibodies and other biologics with a main focus on binding kinetics, in support of drug discovery and clinical development
- Closely collaborate with other discovery groups and serve as an analytical subject-matter expert to enable the design and execution of antibody functional characterization
- Act as a scientific and technical resource on a variety of protein analytical techniques
- Track literature and monitor developments in relevant fields to develop new assays and/or improve existing practices
- Cure Cancer.
Preferred Qualifications:
- Solid technical knowledge and hands-on experience using SPR (Biacore) and/or BLI (Fortebio) for affinity measurement, ranking of binders and epitope binding & mapping
- Experience with biochemical & biophysical methods for protein characterization such as SEC/RP/IEX-HPLC, SEC-MALS, Mass Spec, SDS-PAGE, DSC/DSF
- Microsoft Excel programming skills for data transfer, deposition, analysis and statistical characterization using Prism or Sigmaplot
- Excellent record keeping abilities to adequately document analytical data
- SOPs writing and mentoring junior scientists
- Ability to work in a fast-paced environment, properly manage priorities and maintain timelines for multiple projects
- Strong desire to learn new concepts and techniques
Basic Qualifications:
- B.S./M.S. with 5+ years of relevant experience
Compass Therapeutics offers individually-tailored compensation packages which include competitive cash compensation, meaningful equity participation, comprehensive healthcare and adoption benefits, continuous career development, sabbatical programs, education reimbursement and many other benefits aligned with our philosophy of putting our team first. Our labs are located at 450 Kendall Street in Cambridge, MA.