Org Marketing Statement
All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That's why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.
Role Description
The candidate will lead biology efforts focused on therapeutic approaches involving vessel wall physiology and vascular inflammatory mechanisms in heart failure. This individual will leverage their depth of knowledge and hands-on expertise in studying pathophysiological mechanisms of the vascular system particularly as it underlies cardiovascular disease. This individual will be a key contributor in the cardiovascular group and expected to advance an innovative drug discovery portfolio spanning the continuum of drug development from target identification to advancing assets into the clinic and through Phase 2. The successful candidate will thrive in a fast-paced and goal-oriented, project team environment.
Responsibilities
* Contribute to identifying and advancing innovative new therapeutics approaches for the treatment of heart failure
* Drive preclinical biology through hands on research as well as effective management and mentorship of colleagues
* Effective project leadership built on collaboration with partner lines, vendors, and external experts to impact goals
* Colleague development and supervisory responsibility
* Innovative scientist who will identify and champion novel drug discovery approaches in the vascular inflammation and heart failure spaces.
* Requires excellent written and oral communication skills
Qualifications
* PhD or MD with 4+ years of post-doctoral experience, which may include 3-5 years of industry experience
* Strong record of scientific accomplishment
* Excellent verbal and writing communication skills
Technical Skills Requirements:
Technical proficiency with in vitro and in vivo models of vascular injury, particularly including some of the following:
* Experience in models of vascular injury which may include: atherosclerosis, ischemia reperfusion, myocardial infarction, stroke, wire injury, aortic constriction, pulmonary hypertension, vasculitis, angiotensin or isoproterenol infusion
* Experience with bone marrow transplant/ immune reconstitution techniques, intravital and confocal microscopy, leukocyte trafficking assays and/or preclinical histopathology techniques is desirable
* Experience with endothelial function assessment in preclinical species preferred
* Isolation and characterization of endothelial cells, smooth muscle cells and leukocyte subsets desirable:
* FACS
* Cell isolation from target tissue (atheroma, myocardium, spleen, bone marrow
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Please apply at: Application URL:http://www.aplitrak.com/?adid=QWxpc29uLlR1dGx5cy4yNDQzMi4zMTY3QHBmaXplci5hcGxpdHJhay5jb20