Org Marketing Statement
A career at Pfizer offers opportunity, ownership and impact.
All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.
Role Description
Statistician in a preclinical team focused on all aspects of early preclinical research and development supporting Neuroscience and Pain Research Unit.
The Research Statistician will be an integral member of a team, which develops and uses computational and statistical approaches to validate and discover disease targets, develop assays around these targets, and derive robust biomarkers. The statistician will play a pivotal role at all stages of experiments from design through signal processing to statistical analysis and interpretation.
In this position, the Research Statistician will work within the matrix environment collaborating across multiple groups including discovery biology, electrophysiology, imaging, genetics, computational biology, PK/PD modeling, and informatics. She/he will also interface with statisticians and clinicians whose focus is advancing compounds from lead development through Proof of Concept in the clinic.
Responsibilities
* Collaborate with scientists across WRD, including Neurodegeneration, Neuroinflammation and Psychiatry teams to design, analyze and present results of the experiments
* Bring innovative statistical thinking and methods to help drive data-driven drug discovery and development employing modern methods including Bayesian techniques
* Work with scientists to understand the biology and improve existing or derive new endpoints, utilize prior information, develop 'fit-for-purpose' statistical models
* Serve as a core member of scientific teams responsible for determining strategy and delivering high quality results in a timely manner
* Use statistical expertise to prepare both internal and external reports, presentations, manuscripts
Qualifications
PhD in Statistics, Biostatistics or in quantitative discipline such as Physics, Applied Mathematics, Bioengineering, Electrical Engineering coupled with high level of statistical expertise. Research experience with mathematical/statistical modeling using complex data and five or more years of postdoctoral or industrial experience are preferred.
* Strong background in experimental design and statistical analysis including good understanding of inference and probability, competence in contemporary linear and predictive modeling including (longitudinal) mixed models, nonlinear regression, and predictive modeling
* Expert level knowledge of machine learning algorithms with robust feature selection and optimization
* Experience with development and validation in biomarker studies, including analysis of imaging and/or electrophysiological data
* Comprehensive knowledge of methods of signal processing including image segmentation and/or electrophysiological data analysis
* Genuine interest in biology, preferably Neuroscience.
* The attitude of self-directed scientist; demonstrated ability to multitask
* Outstanding communication skills; ability to explain modeling concepts to non-experts
* Demonstrated ability to work effectively as a part of a team
* Demonstrated ability to effectively deal with ambiguity and change
Technical Skill Requirements:
* Expert level knowledge of statistical programming environments such as R and/or SAS
* Expert level knowledge of scientific programming in MATLAB and/or Python, along with low level languages C/C++/Fortran
* Hands-on experience with high-performance computing, Unix environment, scripting, are preferred
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
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