www.genocea.com

Genocea Biosciences is a small fast-growing vaccine discovery and development company based in Cambridge, Massachusetts. Genocea is harnessing the power of T cell immunity to develop the next generation of vaccines and immunotherapies. 

Sr. Scientist/Group Leader, EBV

Position Summary

Seeking a top notch contributor to join our dynamic and dedicated team. Reporting directly to the Director of Vaccines in the Vaccine Development group, the Sr. Scientist/Group Leader will be expected to apply an understanding of Epstein-Barr virus (EBV) virology and immunology towards the development of new vaccines candidates against EBV. The candidate will contribute with both technical and intellectual expertise to many levels of a program, including antigen screening and prioritization, adjuvant testing, immunization strategies, animal modeling, and external collaborations. The successful candidate will supervise of a team that supports the evaluation of immunogenicity and efficacy of candidate vaccine formulations in animal models and clinical trials. He/she will develop collaborations to advance Genocea’s EBV strategy through strong alliance management, driving publications, and representing the company at key scientific meetings.

Competencies

•  Excellent communication, problem solving and analytical skills
• Deep knowledge of EBV virology and immunology
• Understanding of EBV-associated diseases
• Solid technical knowledge and hands-on experience with immunological and virological techniques
• Experience in vaccine development

Required Skills

• Plan, implement and directly supervise complex projects
• Assist in developing budgets
• Familiarity with current scientific literature and ability to select methods and techniques for obtaining solutions within accepted practices and procedures
• Provide guidance and supervision to multiple direct and indirect reports, demonstrate leadership skills, successfully develop and manage timelines
• Assume lead role in providing solutions to difficult problems associated with specific projects
• Ensure technical quality and compliance
• Participate in development of patentable technology
• Maintain broad knowledge of state-of-the-art principles and theory
• Make important contributions to scientific projects, draft manuscripts for publication, present technical data at scientific conferences
• Exhibit an exceptional degree of sustained ingenuity, creativity and resourcefulness
• Application and/or development highly advanced technologies, scientific principles, theories and concepts that may be new to the industry
• High-level creative problem solving and analytical skills, using technical discretion in the design, execution and interpretation of experiments that contribute to project goals

Education & Experience

MD or PhD with 7-10 years of relevant experience in infectious diseases, immunology, oncology, virology or related field. Relevant experience in industry is a plus.

Please reference that you are applying for the requisition number MSB140

www.genocea.com

Genocea Biosciences is a small fast-growing vaccine discovery and development company based in Cambridge, Massachusetts. Genocea is harnessing the power of T cell immunity to develop the next generation of vaccines and immunotherapies. 

Scientist / Sr. Scientist, Immuno-Oncology

Position Summary

The Scientist/Senior Scientist Immuno-Oncology reports to the Head of Immuno-Oncology. He/she is responsible for the discovery and development of T cell antigens for cancer immunotherapy. In addition, the candidate will identify and develop Immuno-Oncology biomarkers.  S/he will design and perform experiments for internally- and externally-focused research programs. The candidate will effectively and routinely collaborate with colleagues in Discovery and Vaccine Development, as well as present scientific results to multidisciplinary teams and the leadership team at Genocea Biosciences.

The Scientist/Senior Scientist will contribute to the external scientific visibility of Genocea through publications and presentations at key scientific meetings and serve as a subject matter expert in immunology and oncology.

Primary responsibilities

• Work collaboratively with other departments to characterize and identify the specificity of T cell responses to tumors and design and evaluate novel immunotherapies
• Support R&D collaborations as a technical expert and scientific liaison
• Critical interpretation of data, including formulation of suggestions for alternate approaches for data generation and evaluation
• Integration with existing project teams
• Drafting of manuscripts for publication in peer-reviewed journals

Required Skills

• Experience in the development of cancer vaccines, including the evaluation of novel adjuvants and delivery systems is critical
• Expertise in T cell culture, flow cytometric methods, and cell cloning is required
• Experience with molecular biology including RNA, DNA and protein analysis is preferred
• Experience with culture of tumor-infiltrating lymphocytes, in silico epitope predictions, TCR sequencing, and processing of human tumors for next generation sequencing is a plus

Candidate must:

• work independently and manage multiple projects simultaneously
• demonstrate the ability to analyze and present data in professional format
• keep up-to-date with the literature related to his/her field
• demonstrate clear and professional verbal and written communication
• work and communicate effectively in a matrix environment

Education and Experience

A PhD or MD/PhD degree in oncology, immunology or tumor immunology related field, with at least 4 years of post-doctoral or industry experience working in tumor immunology or related field with a demonstrable record of scientific achievement is required

Please reference that you are applying for the requisition number MSB141

www.genocea.com

Genocea Biosciences is a small fast-growing vaccine discovery and development company based in Cambridge, Massachusetts. Genocea is harnessing the power of T cell immunity to develop the next generation of vaccines and immunotherapies. 

Purchasing Administrator (Part-Time, 24-30 hours)

Position Summary

We are looking for part-time purchasing administrator to support the procurement process in a fast paced biotechnology company. The right candidate will have experience with NetSuite; be responsible for the ordering of materials, supplies, and/or equipment; follow through with vendors on shipment and delivery. The candidate will interact with the scientific and administrative staff and process requests in a timely manner.

Primary responsibilities

• Place and process orders
• Reconcile receipt of materials with purchase orders
• Participate in researching and negotiating repetitive purchases.
• Coordinating with suppliers on contracts and reorders of goods and services.
• Monitoring usage history of goods & inventory stock items in coordination with Laboratory Operations staff
• Maintain inventory for office supplies
• Ensure the details of purchase transactions are carried out in a timely fashion
• Follow up on orders to ensure that materials are shipped and delivered on promised dates.

Required Skills

• Have previous procurement process experience and be accustomed to using a computerized system for processing purchase orders
• Be skilled at using Microsoft Excel, Word and PowerPoint
• Demonstrate clear and professional verbal and written communication
• Work and communicate effectively in a matrix environment
• Be detail oriented and possess excellent organizational skills

 Education and Experience

A BS or HS diploma with at least 2 years purchasing experience is required. Experience in the biotechnology field and familiarity with NetSuite or other purchasing software is a plus.

To apply for this position, please CLICK HERE

www.genocea.com

Genocea Biosciences is a small fast-growing vaccine discovery and development company based in Cambridge, Massachusetts. Genocea is harnessing the power of T cell immunity to develop the next generation of vaccines and immunotherapies. 

Senior Research Associate

Position Summary

We are seeking an Associate to join our Research Department in Cambridge, MA.  The ideal candidate is a motivated, energetic, detail-oriented person who will design and carry out experiments with limited supervision.  Position involves making contributions to experimental design and data analysis.  Must have the capacity to adapt, and demonstrate a strong desire to learn new concepts and techniques.  Expected to work well within a dynamic and team-oriented small company environment.

Primary Responsibilities

• Immunological-based techniques including ELISA-based assays, and functional T cell assays (e.g., antigen presentation, ELISPOT, Luminex, multicolor flow-cytometry).
• Animal modeling of infection and vaccination.
• Cell culture and molecular biology techniques (qPCR, western blots, etc).
• Independently design experiments, analyze data and prepare reports.
• Maintain basic knowledge of principals in field(s) at hand.
• Prepare slide decks independently and present them for internal company meetings.
• Maintain literature files and accurate laboratory records and notebooks.
• Troubleshoot experimental process under minimal supervision.

Required Skills

• A solid theoretical understanding of and experience with cellular and molecular immunology techniques. Assay development experience is a plus.
• Proficiency with in vivo mouse models of infection or disease.
• Ability to analyze data, draw conclusions, communicate results and compile technical reports.
• Excellent record keeping abilities to adequately record and document analytical data.
• Solid technical knowledge and hands-on experience.
• Ability to work effectively in a cross-functional setting.
• Capacity to adapt, with a strong desire to learn new concepts and techniques.
• Excellent communication, problem solving and analytical skills. Strong organization and ability to multi-task.

Education & Experience

Master’s degree with a minimum of 3 years or Bachelor’s degree with a minimum of 5 years of experience in biopharmaceutical industry

To apply for this position, please CLICK HERE

www.genocea.com

Genocea Biosciences is a small fast-growing vaccine discovery and development company based in Cambridge, Massachusetts. Genocea is harnessing the power of T cell immunity to develop the next generation of vaccines and immunotherapies. 

Bioassay Scientist

Position Summary

Seeking a top notch contributor to join our dynamic and dedicated team. The Bioassay Scientist will be expected to plan and execute experiments as well as analyze data generated by other internal and external contributors. The candidate will have demonstrated hands-on experience with in vivo and cell-based potency assays, technology transfer, data analysis and troubleshooting. The successful candidate will supervise a small team that supports the evaluation of immunogenicity and efficacy of candidate vaccine formulations both in mouse models and in vitro. He/she will work closely with our Biopharmaceutical Development and Production group to support our vaccine development programs with reliability, integrity, and commitment while working in a cross-functional setting.

Competencies and Responsibilities

•  Provide technical resource for bioassay method development, optimization, implementation and validation.
• Assist with feasibility studies and method transfers within and outside of Genocea.
• Routine review of method performance, design and execution of remediation experiments should discrepancies be identified, and development and implementation of improvements to existing assay methods.
• Assist in maintaining critical reagent supply and instrumentation for assigned methods.
• Write animal use protocols, SOPs, validation protocols, and study reports.
• Work collaboratively across organization and sites for method readiness, transfer, performance and troubleshooting.
• Work closely with Biopharmaceutical Development and Production, Vaccine Development, and Translational Medicine team members to understand their deliverables to achieve organization goals.
• Ability to work independently and as a part of a cross-functional team with a positive attitude.
• Performance of in vivo and in vitro bioassays for vaccine development, comparability, potency, and lot release studies.
• Demonstrated experience with bioassay method development, qualification and validation is necessary.
• Experience with vaccine potency assays is a plus.

Education and Experience Requirements

•  PhD with a minimum of 4 years of relevant experience with bioassays and immunoassays in biologics process development.
• Relevant experience in industry is a must.

To apply for this position, please CLICK HERE

www.genocea.com

Genocea Biosciences is a small fast-growing vaccine discovery and development company based in Cambridge, Massachusetts. Genocea is harnessing the power of T cell immunity to develop the next generation of vaccines and immunotherapies. 

Anti-Microbial Vaccines Sr. Scientist / Group Leader

Position Summary

We are seeking a top notch contributor to join our dynamic and dedicated team. Reporting directly to the Director of Vaccines in the Vaccine Development group, the Sr. Scientist/Group Leader will be expected to apply an understanding of microbial host-pathogen interactions towards the development of new vaccines candidates against Chlamydia trachomatisand Streptococcus pneumoniae among others. The candidate will contribute with both technical and intellectual expertise to many levels of the program, including development of the overall strategy, antigen screening and prioritization, adjuvant testing, immunization approaches, animal modeling, and external collaborations. The successful candidate will supervise a team that supports the evaluation of immunogenicity and efficacy of candidate vaccine formulations in animal models and clinical trials. He/she will develop collaborations to advance Genocea’s vaccine strategy through strong alliance management, driving publications, and representing the company at key scientific meetings.

Competencies

•  Excellent communication, problem solving and analytical skills
• Deep knowledge of microbial pathogenesis, host-pathogen interactions, and animal models of human disease
• Understanding of microbial immunity
• Solid technical knowledge and hands-on experience with immunological and microbiological techniques
• Experience in vaccine development

Primary Responsibilities

• Work collaboratively with other departments to characterize and identify the specificity of T cell responses toChlamydia trachomatis and Streptococcus pneumoniae, and design and evaluate novel vaccines or immunotherapies
• Plan, implement and directly supervise complex projects; assume lead role in providing solutions to difficult problems associated with specific projects
• Perform experiments at the bench to test hypotheses
• Support R&D collaborations as a technical expert and scientific liaison
• Draft manuscripts for publication in peer-reviewed journals
• Budget development
• Ensure technical quality and compliance
• Presentation of technical data both internally and at scientific conferences

 Required Skills

•  Critical interpretation of data, including ability to formulate suggestions for alternate approaches for data generation and evaluation
• Familiarity with current scientific literature and ability to select methods and techniques for obtaining solutions within accepted practices and procedures
• Experience mentoring and managing multiple direct and indirect reports
• Demonstrated leadership skills, with evidence of successful development and management of timelines
• Broad knowledge of state-of-the-art principles and theory
• Exceptional degree of sustained ingenuity, creativity and resourcefulness
• Ability to apply and/or develop highly advanced technologies, scientific principles, theories and concepts that may be new to the industry
• Experience working with both Gram negative (i.e. Chlamydia) and Gram positive (i.e. Pneumococcus) organisms
• High-level creative problem solving and analytical skills, using technical discretion in the design, execution and interpretation of experiments that contribute to project goals

Education Requirements

MD or PhD with 7-10 years of relevant experience in infectious diseases, immunology, microbiology or related field. Relevant experience in industry is a plus.

To apply for this position, please CLICK HERE

Primary Role:
This position actively participates in and assists management in maintaining the quality and compliance of the output of the Global PVRM organization through development and execution of global and departmental processes, PV standards, PVRM training program, and compliance monitoring systems.
Fosters a culture of continuous process improvement and identifies opportunities to further enhance quality and compliance.

Responsibilities:
5%: Maintain and facilitate the collation of a single PV master file and similar documents covering all Shire divisions.

30%: Act as backup or primary if directed by the Head of PV Compliance and Training for Generation of global performance metrics for quality and submission timeliness, including individual case safety report regulatory submission timeliness and aggregate report submission timeliness. Investigate root cause and Identify corrective and preventative actions. Develop process and conduct trend analysis and liaise internally across Shire and externally (alliance partners) to identify root case and CAPA. Identify areas for enhancement of the compliance monitoring process within PVRM. Participate in compliance index and dash board initiative as the PVRM representative. Adequately represent process in procedures and be able to articulate process in audit and inspection interviews. Maintain all documentation inspection-ready. Liaise with management relative to metrics and lead discussions to identify root cause and CAPA.

10%: Assist with audit preparation, document retrieval and tracking, and aid with audit finding responses as directed by the Head of PV Compliance and Training. Participate PVRM related inspections and audits.

20%: Manage the PVQST (owned by Compliance and Training) email box including alerting the Head of PV Compliance and Training to any issues or issues that need the Head of PV Compliance and Training to address. Investigate issues and formulate answers to questions independently and seek advice when necessary.

10%: Manage creation/revision of assigned procedural documents including cross-functional documents. Liaise with PVRM and cross-functional subject matter experts as necessary.

5%: Provide support to globalization and company integration projects impacting the pharmacovigilance system.

5%: Evaluate legislation related to pharmacovigilance; identify gaps with current process; articulate gaps to management as well as identify potential resolution to identified gaps. Ensure changes to legislation are reflected timely in PVRM process documents. Serve as point of contact with contracted vendor for global regulatory intelligence as directed by Head of PV Compliance and Training.

5%: Manage special projects as directed by Head of PV Compliance and Training and/or PVRM management.

10%: Manage curriculum for PVRM staff and identify any gaps or issues. Liaise with Head of PV Compliance and Training related to any issues that may develop. Identify areas for improvement. Liaise with R&D Quality and Compliance to determine PVRM requirements for SOP/Policy training. Work within department to ensure compliance.

Education & Experience Requirements:
o Bachelors of Science Degree preferred in science-related or technical field.
o 3+ years experience in technical writing needed especially procedural documents.
o 1-2 years experience working within a pharmacovigilance system
o Experience with generating and reviewing metrics such as key performance and quality indicators
o Working knowledge of databases
o Basic knowledge of Quality Management Systems as well as FDA/EU regulations and ICH guidelines for GXP or devices

Other Job Requirements: Domestic and international travel will be required (

Shire's Brave culture offers employees with diverse backgrounds the opportunity to enable those with life altering conditions to lead better lives. Shire is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by applicable law. US Applicants who require accommodation in the job application process may contact 484-595-8400.

Please apply at: Application URL:http://www.aplitrak.com/?adid=c3N6Y3plc255LjczNjgyLjMxNjdAc2hpcmUuYXBsaXRyYWsuY29t

Org Marketing Statement
All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That's why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.

Role Description
We are seeking an enthusiastic independent scientist with a demonstrated track record in basic or translational sciences related to obesity/diabetes, who is interested in pursuing an academic style Postdoctoral Fellowship in an industry setting. Scientific training in the fields of endocrinology, metabolism, or neuroscience is ideal.

The scientific focus relates to the study of pathways regulating body weight homeostasis. The goal is to build a deep understanding of central and/or peripheral mechanisms that regulate caloric intake and metabolism utilizing rodent in vivo approaches in conjunction with human tissue models. Publication in high-impact journals and presentation of research is prioritized, however project work may also bring about opportunities to complement drug discovery interests.
The candidate will have daily interactions with a team of creative and innovative scientists in a supportive environment for rigorous scientific training. Mentorship is focused on nurturing skills to enable development as an independent scientific investigator. Strong self-motivation, excellent communication interpersonal skills, and the ability to work independently and as part of a team is essential.

Responsibilities
- conceptualize and design experiments to perform cutting edge research to uncover novel biological mechanisms regulating energy homeostasis
- organize and conduct in vivo/ ex vivo studies independently (including preparation, data collection, interpretation, and presentation)
- author manuscripts for quality publications in top-tier journals.
- attend and present at international meetings and collaborate across groups in the research unit.

Qualifications
EDUCATION AND EXPERIENCE
PhD related to biological sciences. A strong background in endocrinology, metabolism, or neuroscience is preferred. A proven track record of publishing in top tier journals is required.

TECHNICAL SKILLS REQUIREMENTS
Hands-on experience with in vivo rodent experimentation, general molecular biology (PCR), protein detection (ELISA, Western blot) and immunohistological skills. Experience in imaging techniques is a plus.

PHYSICAL POSITION REQUIREMENTS
Flexible working hours.
Rodent work.
Handling human tissues.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Please apply at: Application URL:http://www.aplitrak.com/?adid=ZWRkeS5uaWNvbGFzLjIzMzk2LjMxNjdAcGZpemVyLmFwbGl0cmFrLmNvbQ

Org Marketing Statement
A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description
Post-doctoral Research Fellow in Analytical and Bioprocess Research and Development the successful candidate will be responsible for developing, optimizing and applying a variety of analytical methods designed to rapidly characterize N-linked oligosaccharide structures on test monoclonal antibodies and determine nucleotide sugar levels in cell culture samples. The candidate will also be responsible for employing cell and molecular biology techniques aimed at modulating N-linked oligosaccharide structures. The position is shared between the Analytical Research and Development and the Bioprocess Research and Development groups in the Biotherapeutics Pharmaceutical Sciences department. These groups are partnering in collaboration with an academic research lab in Cambridge, MA to understand the systems and synthetic biology concepts and tools required to control the N-glycan profile of monoclonal antibodies expressed in CHO production cells. The goal of the work is the
development of methods in support of this collaboration. The candidate will be expected to evaluate existing methodology and then further develop, optimize and or apply as necessary to satisfy the analytical needs of the collaboration. The desired outcome is the publication of results in peer-reviewed journals and presentations at scientific conferences.

Responsibilities
The qualified candidate will be responsible for developing, optimizing and applying a variety of analytical methods designed to rapidly characterize N-linked oligosaccharide structures on test monoclonal antibodies and determine nucleotide sugar levels in cell culture samples. Thorough research of contemporary literature regarding high throughput analysis of N-linked glycans and nucleotide sugars and application/advancement of state of the art techniques documented within the literature is expected. The candidate will be expected to assist in applying learning from the analytical analysis by designing and executing experiments using cell culture models to modulate N-linked glycans. The candidate will also be expected to work with cell line development colleagues at Pfizer or in an academic lab to develop sample handling procedures designed to minimize sample handling artifacts and generate samples that are most representative of the cell's metabolic state. The qualified candidate will be expected to collaborate with multiple groups within Pfizer and with an external academic lab. The candidate will be expected to generate data and contribute to manuscripts for publication in peer-reviewed journals and to presentations at scientific conferences.

Qualifications
PhD in Chemistry, Biochemistry or related fields required. A strong background in N-linked glycan analysis and small molecule separations is required. This includes experience with high performance liquid chromatography and mass spectrometry at a minimum. Experience with high throughput analytics is desirable. A strong understanding of the glycosylation pathways in mammalian cell systems is required. A working knowledge of cell and molecular biology and cell culture techniques is desirable. Strong written and verbal communication skills are required. A strong history of publications in peer-reviewed journals and presentations at national conferences is desired.

PHYSICAL/MENTAL REQUIREMENTS
The position will require that the colleague perform routine lab tasks such as pipetting, standing or sitting at a lab bench for extended periods of time and walk up and down stairs in order to move from one lab to the next. The position will also require that the colleague perform complex data analysis and work at a computer for extended periods of time.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
The colleague will be expected to perform most of their work at the Andover facility but will also be expected to attend meetings in Cambridge at least twice a month. The colleague will be expected to present at external conferences, which may require travel.

EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Please apply at: Application URL:http://www.aplitrak.com/?adid=ZWRkeS5uaWNvbGFzLjA4MTA5LjMxNjdAcGZpemVyLmFwbGl0cmFrLmNvbQ

Org Marketing Statement
A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description
Pfizer is developing small-molecule compounds to treat the basic defect in cystic fibrosis (CF) which involves misfolding of the CFTR chloride channel. We are seeking a Senior Associate Scientist to measure the activity of CFTR modulators using cell-based assays of CFTR function.
The candidate will evaluate compounds using assays on primary airway cells from CF patients. The work will involve designing experiments, dosing compounds, performing assays, analyzing the results, and assessing the reproducibility of the data. The candidate will help optimize these assays and maintain prototype instrumentation. The candidate will work closely and collaboratively with other colleagues, requiring proactive communication and a teamwork mentality. Electrophysiology experience is desirable but not required. A strong candidate will have experience in mastering multiple cell-based assays in a drug discovery setting, preferably requiring the use of lab automation, and a demonstrated track record of learning and applying new skills.

Responsibilities
She/he will be responsible for delivering high quality data to the project team, presenting results at meetings, and adapting work flow to the needs of the program. The successful candidate will make use of problem solving, critical thinking, and effective written and oral presentation skills in a dynamic, multidisciplinary team environment.
* Design experiments in consultation with supervisor.
* Independently perform electrophysiology experiments.
* Report results at team meetings.
* Maintain a compound inventory and testing queue.
* 5) Train and collaborate with junior colleagues and student interns.

Qualifications
Required:
M.Sc. in Biology with 2+ years' experience in a drug discovery setting or B.Sc. in Biology with 4+ years' experience in a drug discovery setting

Physical Requirements:
Work involves sitting, standing, and walking.

Schedule/Travel Requirements:
Weekend work will be required occasionally. Occasional travel to meetings and conferences is involved.

EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Please apply at: Application URL:http://www.aplitrak.com/?adid=QWxpc29uLlR1dGx5cy40NDMzNC4zMTY3QHBmaXplci5hcGxpdHJhay5jb20

Org Marketing Statement
A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description
The Research Statistics group collaborates across a wide variety of activities in the early phases of drug discovery. This position is located in Groton CT and has a focus on the optimization of chemical matter and the development of assays to characterize these molecules

Responsibilities
The successful candidate will:
* Demonstrate leadership in influencing and improving drug discovery by identifying, developing, and applying new quantitative methods.
* Proactively seek collaborations with scientists and lab heads.
* Collaborate with scientists to plan meaningful studies, statistically analyze, and communicate / document the results.

Qualifications
Minimum Qualifications:
* M.S. or Ph.D. in Statistics, Biostatistics, or related field and 2+ years statistical consulting experience in drug discovery and development, preferably in a laboratory science environment.

Desired Qualifications:
* Five or more years experience in the pharmaceutical industry.

PHYSICAL/MENTAL REQUIREMENTS:
Minimum Requirements:
* The ability to proactively seek collaborations with scientists and lab heads.
* Strong initiative, excellent interpersonal and communication (written and verbal) skills
* Understanding of inference and probability; competence in contemporary linear modeling including mixed models, nonlinear regression; and predictive modeling/machine learning.
* Solid understanding of experimental design
* An understanding of tools for the analysis of high dimensional data
* Strong computational skills in R

Desired:
* Sound understanding and experience of applying Bayesian methods
* Formal training in, or thorough understanding of: human physiology, cell biology, pharmacokinetics and/or pharmaceutical chemistry.
* Strong computing skills in scripting languages, such as perl, python, unix shell scripts or others. SQL and LaTeX skills are also advantageous.

EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Please apply at: Application URL:http://www.aplitrak.com/?adid=SmFtZXMuQ3JvbmluLjA3ODE2LjMxNjdAcGZpemVyLmFwbGl0cmFrLmNvbQ

Job Description:

We are seeking a talented and dedicated Laboratory Technician who is interested in joining a highly dynamic and intellectually challenging work environment and ready to multi-task within scope. The successful candidate will have experience in standard laboratory procedures and will be intimately involved in the successful operation of a multifunctional laboratory environment.

Basic responsibilities:

• Point person for scientific staff; will train on the lower end lab tasks
• Responds to emergency alarms after hours
• Glass wash responsibilities:

1. Ensures a smooth and efficiently run glassware operations
2. Ensures that glassware cleaning eliminates contaminations and allows the scientists to achieve results that are accurate and consistent
3. Works to avoid delays and ensures proficiency in Glass wash production
4. Facilitates others so everyone in the lab understands how glassware support our scientific needs

• Ensures a safe working environment whereby meets or exceeds OSHA and FDA Regulations
• Manages supply inventory and performs the ordering and receiving in company online software (VWR, Invitrogen, inventory of key supplies/reagents such as CO2 and dry ice as trained and requested).  Follows up on back orders.
• Receives all Evelo packages from loading dock or front door and stores them according to specific needs of the contents and manages all returns.
• Waste management BIO (empty individual biohazard bins, interface with Safety Partners to maintain waste room and schedule pick-ups, DOT trained)
• Interface with specific lab vendors such as Stericycle, Veolia, Delaney Linens and Gas Vendors
• Conducts lab support for autoclave, dishwash, buffer and reagent prep and maintain BL2 areas
• Under supervision will call for equipment servicing and manage all service calls
• Maintain and organizes freezers and refrigerator cleanliness (ex: defrost freezers, refrigerators, clean incubators)
• Scanning, barcoding and tube labeling
• Keep whole laboratory stocked with required items

Desired skills and experience:

• Organized, efficient and solution oriented
• Can do attitude and can handle a multi-tasking environment
• Excellent communication and inter-personal skills, team player spirit

Education and work experience:

• Associates degree in Lab Technology preferred
• 2-5 years of relevant experience in academia or industry
• GLP certifications a plus

About Evelo

Evelo Therapeutics is dedicated to transforming cancer therapy through a deep understanding of the cancer microbiome. Evelo is discovering and developing Oncobiotic™ therapies, novel treatments designed to attack cancer by disrupting the microbial envrionment which supports tumors and protects them from the body's immune system. Evelo's platform disrupts the tumor microenvironment at the metabolic and stromal levels and provides next-generation, microbiome-based immunotherapeutics. Founded at Flagship VentureLabs, Evelo is the first microbiome company foscused on cancer. For more information, please visit www.evelotx.com.

Editas Medicine is a transformative genome editing company with a mission to translate its genome editing technology into a novel class of human therapeutics that enable precise and corrective molecular modification to treat the underlying cause of a broad range of diseases at the genetic level. 

We are seeking a highly motivated and innovative research associate with molecular biology and cell culture expertise to support the development of gene editing-based therapies. The successful candidate will contribute as part of a dynamic, multidisciplinary discovery team dedicated to the development of a novel class of therapeutics. The successful candidate is expected to have proven practical experience in molecular biology and mammalian cell culture. The candidate should be a scientifically motivated self-starter, capable of independently conceiving, conducting, and critically analyzing his/her own innovative research with minimal supervision. Strong presentation skills, communication and the ability to work in a fast-paced and team-oriented environment will also be vital.

Minimum Requirements

·       B.S. in cell or molecular biology with 3-5 years post-degree research experience, M.S. preferred

·       Extensive expertise in molecular biology, with hands-on skills such as primer design, PCR, plasmid construction/cloning, Gibson assembly, genomic DNA extraction, RNA isolation, qPCR

·       Proven expertise in mammalian cell culture, transient transfections, cell-based assays, and other basic techniques such as ELISAs and Western Blots

·       Experience with flow cytomety and imaging assays a plus

·       Hands-on expertise with DNA analysis software (VectorNTI, Lasergene, Geneious) preferred

·       Excellent attention to detail

·       An ability to work in a team-oriented, multidisciplinary environment

The Company:

Calvert Laboratories, Inc., a nonclinical development Contract Research Organization (CRO) offers comprehensive services in Toxicology (Acute, Subchronic, Chronic, Carcinogenicity, Developmental, Reproductive and Multi-Generation), General Pharmacology, Discovery Pharmacology, Safety Pharmacology, Immunology, Immunotoxicology, Pharmacokinetics/Toxicokinetics and ADME.  Calvert Laboratories is considered by many to be a premier ‘first-into-man’ contract research organization, has been in business for over forty-five years and enjoys an excellent regulatory history.

The Opportunity:

The Director, Business Development will assume complete responsibility for developing new and strategic clients identified individually and in conjunction with the VP, Commercial Operations and the VP, Business Development.  Key to the success of Calvert’s growth is maintaining long-term relationships between our clients while constantly developing new business opportunities.  Establishing strong business relationships between targeted clients and Calvert’s scientific staff will drive successful sales objectives and long term company expansion. 

This position is directed toward significantly expanding the Company's presence in the Boston territory and offers the opportunity for an account executive to gain and/or develop knowledge of non-clinical drug development.  The Director, Business Development is responsible for establishing and executing tactical and strategic account plans toward achieving the company’s sales objectives in the Toxicology, Pharmacology, Immunology and Metabolism services.   This position will focus on emerging pharmaceutical and biotech companies and requires prospecting and penetrating skills to gain access to our target segment.

Essential Responsibilities:

Meets or exceeds sales goals for the territory. 

Ability to effectively communicate Calvert’s value proposition to prospective pharmaceutical and biotech companies.

Conduct a minimum 15-20 face to face client meetings per month.

Continually develop technical knowledge of Calvert’s services to effectively promote the company’s business and position Calvert favorable to our competitors. 

Develop new and existing business and sales strategies for Calvert’s services in conjunction with senior management.   

Provide forecasts, competitive activity, call and expense reports and document sales activity as required.

Essential Qualifications:

Bachelor degree in Science.  Advanced degree preferred.  Knowledge of drug development required and essential to success.   A strong desire to learn non-clinical drug development.

Living in or relocation to the Boston area required.

A minimum of 2-4 years of successful business development sales experience selling to major pharmaceutical and biotech accounts, especially CRO services.  Pharmaceutical, laboratory and diagnostic sales experience will also be considered.  Will also consider CRO Client Service or inside sales experience.

An understanding of contract negotiation and request for proposal (RFP) process.

Effective presentation and communication skills and the ability to persuasively communicate with senior management across Calvert and client base.

The ability to drive profitable sales and identify viable business targets by understanding the client’s business need and successfully translating their need into opportunities

Demonstrated track record of success, including tactical and strategic account and territory plans.

The ability to focus on key accounts, top opportunities, and manage territory and the sales funnel.

Good organizational skills and the ability to set priorities and manage time effectively.

Travel up to 50% of the time as this territory and the requirements to meet the desired outcomes are extensive. 

Ethical leader with the ability to work in a face paced, demanding environment.

Knowledge and use of a CRM such as SalesForce.

To Apply:

Please submit your resume and examples of your work to joe.winslow@calvertlabs.com. Include the job title in the subject line of your email.  Compensation package commensurate with background and experience.   Please include salary requirements and cover letter.

Calvert is an equal opportunity employer offering a competitive salary and benefits package. To qualify, applicants must be legally authorized to work in the United States, and should not require, now or in the future, sponsorship for employment visa status.

Learn more about Calvert Labs and other Calvert companies at: www.calvertholdings.com

We are seeking a Director/Manager of Accounting to join the Finance team.  The Director/Manager of Accounting reports to the Controller and key responsibilities include assistance in monthly close process and financial reporting, including the development of public company policies and procedures.  The ideal candidate will be a highly organized individual with strong attention to detail and a sound understanding of accounting, financial reporting and internal controls.   The individual should enjoy working in a fast-paced and rapidly growing environment.

Responsibilities:

• Assist in monthly close process, including management of the monthly accrual process
• Assist in developing the patient accrual methodology and establish the clinical trial accrual process
• Participate in accounting for activities under existing and future collaboration agreements
• Assist in the preparation of monthly financial statements and analysis versus budget
• Assist in calculation of quarterly stock-based compensation expense
• Assist in administration of Company equity programs
• Participate in enhancement of accounting policies and procedures
• Work with external auditors on quarterly reviews and year-end audit
• Conduct technical accounting research and document the Company’s accounting analysis
• Supervise Staff Accountant
• Assist with special projects as may arise

Qualifications:

• Accounting degree with CPA certification
• At least 5 years’ experience, preferably with a background in public accounting
• Strong technical accounting skills and knowledge of US GAAP and financial reporting
• Ability to prepare quarterly and annual SEC filings
• Experience with the developmentand maintenance of an effective system of internal controls and compliance with Section 404 of the Sarbanes-Oxley Act
• Ability to work collaboratively and effectively with others
• Ability to work under pressure and meet deadlines
• Strong analytical and communication skills
• Well organized and detail oriented

Job ID: 27428
Date Posted: 12/07/2015
Location: Building HM
Job Family: Technician/Technologist
Full/Part Time: Full-Time
Regular/Temporary: Regular
About Dana-Farber

Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Overview

The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

Our Core Values are:

Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

Compassion and respect - For those in our care and for one another.

Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.

The laboratory of Dr. Constantine Mitsiades, Principal Investigator (P.I.) at Dana-Farber Cancer Institute and Assistant Professor at Harvard Medical School, is seeking an experienced, ambitious, and highly motivated technician to support ongoing projects which investigate the role of the tumor microenvironment in both cancer growth, and responses to various therapies.

The technician would work under the direction of Dr. Mitsiades and Dr. Eugen Dhimolea (Instructor in Medicine, Dana-Farber and Harvard Medical School), and with other lab personnel, performing a variety of research-related tasks. The position offers the opportunity for excellent in-depth training in a wide range of cell culture systems, animal models, molecular biology, and biochemical techniques in our state-of-the-art laboratory.

The position requires self-motivation, excellent organization skills, and strong experimental skills. Prior experience with cell culture techniques, cell growth and reporter assays, transfections, molecular biology/cloning, immunohistochemistry (IHC) and/or animal handling (stereotactic cell injections), as well basic Office Excel knowledge, are highly desired. Rapidly achieving proficiency with complex instrumentation is expected.

Schedule

M-F, 40 hours/week

How to Apply

Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.

Equal Employment Opportunity

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

Apply Here

PI92483040

 Applied DNA Sciences, Inc

DIRECTOR DNA SALES

Position Summary:  Promotes custom DNA manufacturing services using patent-pending Triathlon™ production system. The Triathlon™ is the first system and process to enable the polymerase chain reaction (PCR) to be used for the large-scale manufacturing of DNA sequences. Working closely with customers, this position allows Applied DNA Sciences to respond rapidly to their novel applications for PCR products with a high-quality product and excellent turnaround time.  Applications include DNA Ladders, Linear Gen Expressions. Diagnostic Standards, Aptamer Screening, DNA bar-coding, Direct evolution, RNA, Probes, Research, Libraries, Gene Therapy, DNA Vaccines.  Builds DNA vertical, negotiates contracts with the aim of maximizing sales profits.

Essential Duties and Responsibilities: To perform this job successfully, an individual must be able to perform the following satisfactorily; other duties may be assigned. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

• Develops and implements strategic sales plans to accommodate corporate goals.
• Directs sales forecasting activities and sets performance goals accordingly.
• Reviews market analyses to determine customer needs, price schedules, and discount rates.
• Directs staffing, training, and performance evaluations to develop and control sales program.
• Directs channel development activity and coordinates sales distribution by establishing sales territories, quotas, and goals.
• Directs product simplification and standardization to eliminate unprofitable items from sales line.
• Represents company at trade association, biotechnology, and university meetings to promote Triathlon™ DNA product.
• Delivers sales presentations to key clients. 
• Maintains relationships with key clients and contacts. 
• Assists other departments within organization to prepare manuals and technical publications.
• Prepares periodic sales report showing sales volume, potential sales, and areas of proposed client base expansion.
• Monitors and evaluates the activities and products of the competition.

 Qualifications:

 Education/Experience:

Master's degree or equivalent; or four to ten years related experience and/or training; or equivalent combination of education and experience.

Senior level sales experience in Bio-Pharmactucial sales.

Language Ability:

Read, analyze and interpret scientific and technical journals, financial reports and legal documents. Respond to inquiries or complaints from customers, agencies or members of the business community. Write speeches and articles for publication.

Mathematical Ability:

Calculate figures and amounts such as discounts, interest, commissions, proportions, percentages, area, circumference and volume. Apply concepts of basic algebra and geometry.

Reasoning Ability:

Solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists. Interpret a variety of instructions furnished in written, oral, diagram, or schedule form.

Computer Skills:

To perform this job successfully, an individual should have excellent knowledge of Microsoft Office; MS Word, MS Excel.

Certificates and Licenses:

No certifications needed

Our client is a biopharmaceutical company with a strong history of successful drug discovery and commercialization. They are looking for a detail-oriented, experienced, and responsible individual to help the Global Patient Safety team as a Senior Pharmacovigilance Specialist.

You will have the opportunity to review and interpret all new and follow up documentation to add to the Global Safety Database as well as ensure that all international regulations are followed per PV procedures.  You will also interface with study sites to make sure they are in compliance as well as work with senior department members with signal detection activities.  The ability to be cross team functional is a large piece of this opportunity.

Requirements:

• B.S. in a scientific field (or equivalent degree) and 3 – 5 years of work and clinical trial experience, or

• PharmD, and 2 – 4 years of relevant work and clinical trial experience

• Experience with Clinical Trials and Post-Marketing Database Workflow

• Sound ability to communicate effectively in a matrix environment while maintaining a strong sense of responsibility to work autonomously

• Proficient in safety database navigation

About StratAcuity
Whether you are seeking a career change or simply interested to become part of our network, you will appreciate the ethics guiding each StratAcuity team member. We build lasting relationships with exceptional scientists and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a StratAcuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

CHEMISTRY IS EVERYTHING™

New England Research Institutes (NERI) was founded in 1986 and has grown to become a research organization with a global reputation for high-quality research, innovative thinking, and the use of state-of-the-science tools and techniques. NERI continues to be a leader in public health research, clinical trials management, epidemiology, and state of the art media and dissemination research.

NERI's uninterrupted growth and success has been driven by strong leadership, disciplined attention to scientific integrity, and its ability to attract and retain exceptionally talented staff members. The depth of experience, skill, and expertise that the entire NERI staff brings to each project is what sets NERI apart from other research organizations and is what continues to propel NERI through the 21st century.

We currently have an opening for a full time Sr. Clinical Data Manager. In that position, the Sr. Clinical Data Manager will:

• Oversee data management activities to ensure that the clinical trial team and statistical expectations are understood, timelines are met and communication remains open; 
• Work cooperatively and constructively to develop effective solutions to operational data management problems. Monitor the quality of data management deliverable and track problems to resolution; 
• Coordinate and supervise project staff involved in all data management activates/objectives within a study. Train staff and set project timelines for data management activities; 
• Assist in the dissemination of results/findings and maintain communication patterns with physicians, hospital staff and study sponsors; 
• Act as a liaison with all study members and other functional groups on all levels on technical requirement for database development and data quality within a study; 
• Actively contribute to the review of working practices and data management SOP's and demonstrate GCDMP knowledge and practices.

Qualifications: 

• Bachelor degree in social, biological or computer science and 3-5 years of significant data management experience or a MPH and 2+ years of significant data management experience; 
• Demonstrated ability to coordinate and monitor the quality of research data collected; 
• Proven skills in a variety of data management software such as SAS and/or commercially available EDC/ CTMS systems; 
• Excellent communication skills---both oral and written; 
• Proficiency in Microsoft Office applications. 

NERI is an Equal Opportunity Employer and considers qualified applicants for employment without regard to race, color, creed, religion, national origin, sex, sexual orientation, gender identify and expression, age, disability, Vietnam era or other eligible veteran status, or any other protected factor.

For more information, or to apply now, you must go to the website below. Please DO NOT email your resume to us as we only accept applications through our website.

https://neriscience.applicantpro.com/jobs/245214-19107.html