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Career postings for the Massachusetts Biotechnology Council

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    Position Summary
    We seek a highly skilled and motivated senior scientist who is an expert in modern proteomics. The candidate will expand the capabilities of our existing LC/MS laboratory and establish new state of the art tools with the goal of characterizing therapeutic and endogenous proteins, as well as protein-mRNA interactions. The Proteomics Sr. Scientist will work with other Moderna scientists and external groups to expand the fundamental understanding of the impact of exogenous mRNA-directed therapeutic protein generation on disease biology.

    Responsibilities
    * Expand state of the art proteomics laboratory
    * Establish peptidomics- and proteomics-based strategies for characterization of exogenously delivered mRNA-cellular protein interactions
    * Apply new methodologies for characterization of mRNA-encoded proteins
    * Hire and supervise proteomics scientific staff members

    Minimum Qualifications
    * Ph.D. in chemistry, biochemistry, cell biology or a related discipline
    * Extensive experience with mass spectrometry with 5 years of postdoctoral/industrial experience
    * Ability to manage, maintain, and employ Orbitrap-based mass spectrometry platforms, as well as experience in HPLC/Auto-sampler utilization
    * Experience with computational tools for protein identification, statistical analysis and visualization/interpretation of mass spectrometric data
    * Proven experience with LC/MS analysis of biological samples derived from in vitro and in vivo sources
    * Knowledge of affinity purification techniques for isolation of biomolecules; experience in handling mammalian cells
    * Willingness to engage and ability to coordinate multiple collaborative projects in a cross-functional team environment
    * Experience in quantitative approaches including MRM, PRM and reference peptide analysis

    Preferred Qualifications
    * Ph.D. with at least 8 years of industry experience in protein sciences
    * Relevant publications in peer-reviewed journals expected in support of candidacy
    * Familiarity with mRNA biology
    * Ability to multi-task to meet technology development and research goals

    Competencies
    * Effective Communication
    * Independence/Teamwork
    * Applied Learning
    * Customer Focus
    * Ability to inspire and supervise staff members
    * Technical/Professional Knowledge

    Why Join Moderna
    Moderna is pioneering messenger RNA Therapeutics™, an entirely new in vivo drug modality that produces human proteins or antibodies inside patient cells, which are in turn secreted or active intracellularly. This breakthrough platform addresses currently undruggable targets and offers a superior alternative to existing drug modalities for a wide range of disease conditions. Moderna has developed a broad intellectual property estate, including more than 250 patent applications covering novel nucleotide chemistries and drug compositions. The company plans to develop and commercialize its innovative mRNA drugs through a combination of strategic relationships as well as newly formed ventures.

    Founded in late 2010 by Flagship VentureLabs, Cambridge-based Moderna is privately held and currently has strategic agreements with AstraZeneca and Alexion Pharmaceuticals.

    Moderna recently signed a collaboration agreement with Astra Zeneca that provided a $240MM upfront payment (plus milestone payments).

    Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

    Application URL:http://www.aplitrak.com/?adid=YWxsaXNvbi5tYXllci43MTk2OS4zMTY3QG1vZGVybmF0aGVyYXBldXRpY3NpbmMuYXBsaXRyYWsuY29t


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  • 12/11/15--06:48: Director Toxicology
  • BASIC SUMMARY: 

    Responsible for leading the site toxicology organization, overseeing site toxicology scientific resources, and providing scientific expertise for the site toxicology group.  Serve as a member of the Global Toxicology Governance Committee and Site Leadership team.  Direct Scientific Directors, Study Directors and Toxicology Study Operations team to ensure high scientific quality, protocol adherence, integrity and full GLP compliance of general toxicology studies, as applicable.

     

    ESSENTIAL DUTIES AND RESPONSIBILITIES: 

    • Provide overall scientific and operational leadership to the site toxicology organization overseeing toxicology scientific resources and toxicology study operations at the site.
    • Serve as a member of the Global Toxicology Governance Committee to resolve issues and identify and advance standardization/optimization of toxicology operations and procedures. 
    • Supervise Study Directors, Study Operations and Archives in their interactions with Sponsors, design of studies, preparation of protocols, interpretation of data and preparation of study reports.
    • Assist with Study Director assignments and workload balancing, study scheduling, and report tracking.
    • Foster the training, professional development and scientific credentials of the Toxicology department at the site.
    • Institute processes to optimize toxicology study execution.
    • Represent Charles River and the site to potential new clients.
    • Work closely with direct and indirect reports to achieve/maintain a high level of integrity in all aspects of customer service, effective communications and study execution. 
    • Develop and implement plans/actions to continuously identify and reduce costs in toxicology and related areas.
    • Contribute to the development of major business proposals for key clients as required.
    • Perform Testing Facility Management duties as delegated.
    • Direct activities of assigned group(s) to ensure optimum performance of the group/function.
    • Responsible for personnel management activities such as: scheduling, personnel actions (hiring, promotions, transfers, etc.), training and development, providing regular direction and feedback on performance, disciplinary actions and preparing and delivering annual performance and salary reviews.
    • Develop short- and long-range operating objectives, organizational structure, staffing requirements and succession plans.
    • Integrate activities with those of other major organizational units (e.g. segments, departments, functions).
    • Develop and recommend departmental budget and authorize expenditures.
    • Develop and oversee the implementation of departmental training programs, including orientation.
    • Support the policy of equal employment opportunity through affirmative action in personnel actions.
    • Partner with site senior leadership team in the development and implementation of succession plans of key toxicology personnel.
    • Responsible for ensuring client expectations are met and issues involving study conduct or reporting are resolved in a way that maximizes client satisfaction.
    • Direct the development and communication of systems, SOPs, policies and procedures, as appropriate.
    • Perform all other related duties as assigned.

     

     

    Study Director Duties

     

    • Serve as a Study Director when appropriate.
    • Generate study protocols for various regulatory guidelines and obtain sponsor approval.
    • Assure that the protocol, including any change, is approved as provided by the GLP’s and is followed.
    • Supervise the conduct of the studies; assures all applicable good laboratory practice regulations are followed.
    • Assure that all data for the studies are accurately recorded and verified.
    • Keep both management and the sponsor informed as to any significant protocol changes or circumstances that may affect the quality and integrity of the study and documents the corrective action taken.
    • Interpret, analyze, document and report the results for toxicology studies.
    • Ensure that at the end of the study all raw data, supporting documentation, protocols, specimens and final reports are archived.
    • May act as an interim or alternate study director in the event the assigned study director is unavailable.
    • Submit reports in a timely fashion.
    • Perform all other related duties as assigned.

     

            Safety and Health

     

    • Conform to all relevant safety information, within area of responsibility, including use of specialized safety equipment required by Standard Operating Procedures (SOP), protocols, and OSHA regulations.
    • Reduce or eliminate possible hazards with input from Health and Safety Officers on any new or changed procedures in the work place.
    • Inform affected employees of special safety precautions via verbal and written notification and see that any additional safety training is provided prior to the conduct of the study.
    • Responsible for appropriate safety gear worn by employees.

     

    QUALIFICATIONS:

    • Education:  An advanced degree (M.S., Ph.D. or equivalent) in toxicology or related field required. 
    • Experience:  At least ten years of relevant scientific and management experience in the pharmaceutical or contract research fields in a GLP environment in scientific and project management roles.  An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
    • Certification/Licensure:  Board Certification in Toxicology (D.A.B.T.) highly desired.
    • Other:  Ability to critically evaluate written scientific documents for overall quality, clarity of presentation, and acceptability of scientific interpretation. Ability to handle multiple projects, prioritize work and meet deadlines.  Excellent written, verbal and problem solving skills.  Good interpersonal skills which are conducive to effective communication and delegation

     

     

    PHYSICAL DEMANDS:

    • Must regularly operate a computer and occasionally operate other office productivity machinery such as a calculator, copy machine, and computer printer.
    • Must regularly communicate with employees/customers; must be able to exchange accurate information.
    • Must occasionally move about inside the office to access file cabinets, office machinery, etc.
    • Specific vision abilities required by this job include close vision and the ability to adjust focus.

     

    WORK ENVIRONMENT:

    • General office working conditions, the noise level in the work environment is usually quiet.
    • While performing the duties of this job the employee may occasionally be required to wear protective clothing (goggles, face shield, surgical mask, cap, gloves, scrubs, boots), work near toxic or caustic chemicals, work with biohazards, and/or work with live animals with risk of exposure to allergens and/or zoonotic diseases.
    • The employee may occasionally be exposed to fumes or airborne particles, unpleasant odors, and/or wet, humid and/or extreme temperature conditions.

     

    Comments:

    • This position requires occasional domestic or international travel.

    Equal Employment Opportunity

     

     

    Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet


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    Research Associate/Senior Research Associate, Immunology

     

    The successful candidate will work with the Equipoise Therapeutics team to develop novel therapies that stimulate immune responses against both solid and hematologic cancers.

     

    Responsibilities:

    • Primary immune cell isolation, particularly T and NK cells, and propagation in cell culture
    • Culture of cancer cell lines and development of cell line derivatives
    • Assay phenotype and sort immune cells with multi-parameter flow cytometry
    • Assay functions of immune cells (e.g. cell killing and cytokine production) in cell culture
    • Perform cell and molecular biology experiments
    • Perform in vivo work in mice
    • Plan experiments and coordinate with others when needed
    • Generate, analyze, interpret, and present experimental data
    • Manage daily work flow independently and seek advice when appropriate
    • Stay attentive but flexible with deadlines
    • Work collaboratively with the Equipoise team

     

    Qualifications:

    • B.S. or M.S. degree in immunology, molecular biology, or relevant field
    • 3+ years of relevant research experience, industry experience preferred
    • Strong background in immunology, cell and molecular biology, or cancer biology
    • Demonstrated mastery of primary cell culture of non-adherent cells, preferably lymphocytes
    • Experience with basic molecular biology and biochemistry techniques as well as flow cytometry
    • Proficiency with data analysis methods and software
    • Strong organizational and record keeping skills
    • Ability to multi-task with a high attention to detail
    • Ability to work in concert with a team as well as independently
    • Excellent written and verbal communication
    • Self-motivated, conscientious, and enthusiastic about curing cancer

     

    Equipoise Therapeutics is a discovery-stage company that aims to stimulate immune responses against cancer. We are developing novel first-in-class therapeutics targeted at natural killer cells as well as other cells of the innate immune system. These therapies are designed to counterbalance immune suppressive factors present in the tumor microenvironment and mobilize anti-cancer immune responses. Our molecules are expected to be potent as single agents as well as in treatment combinations with existing cancer immunotherapies. Our scientific founders are major figures in cancer biology and immunology and have launched Equipoise to effectively harness the power of the immune system to provide durable cancer treatments for patients.

     

    Please send your cover letter and resume to: join@equipoisetherapeutics.com.

    Updated December 10, 2015.

    Equipoise Therapeutics | One Kendall Square | Bldg 200, Suite 2203 | Cambridge, MA 02139 | equipoisetx.com


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  • 12/10/15--22:00: Senior RA Discovery, Biology
  • If you are a motivated researcher who is curious as to the "why" of a discovery program then please read on!  We are looking for an independent scientist to join our growing company and help drive this therapeutic to patients

    Requirements:

    • BS/MS degree with 3-10 years experience (junior PhD candidates will be considered as well).

    • Design and conduct cell-based assays (viability and apoptosis), perform WB and qPCR, as well as collaborate to execute MS based metabolomic endpoints to drive early discovery.

    • Engineer cell lines (stable knockdown and/or overexpression via RNAi and viral methods) for target engagement interrogation.

    • Good lab citizenship, excellent record keeping and attention to detail, a drive to learn and grow professionally.

    About StratAcuity
    Whether you are seeking a career change or simply interested to become part of our network, you will appreciate the ethics guiding each StratAcuity team member. We build lasting relationships with exceptional scientists and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a StratAcuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

    CHEMISTRY IS EVERYTHING™


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  • 12/10/15--22:14: Medical Writer
  • The Medical Writer is responsible for preparing moderately complex clinical study documents and sections of regulatory submissions. The Medical Writer may assist other Medical Writing staff to prepare more complex documents and may assist with developing documents produced by other departments.
    KEY RESPONSIBILITIES:
    - Prepare routine clinical regulatory documents, including clinical study protocols, clinical study reports, and investigator’s brochures, and sections of regulatory submissions
    - Assist with preparing more complex documents
    - Serve as the lead medical writer for routine clinical studies
    - Coordinate the efforts of cross-functional teams to produce high-quality, scientifically accurate documents and ensure consistency between related documents
    - Manage timelines and communicate with team members to maintain awareness of expectations, milestones, and deliverables
    - Review documents, including those authored by other functions
    TECHNICAL AND COMMUNICATIVE SKILLS:
    - Excellent written communication skills
    - Experience producing high quality scientific/medical documents
    - Ability to analyze, interpret, and summarize data
    - Basic understanding of drug development, clinical research, study
    design, biostatistics, pharmacokinetics, regulatory requirements, and medical terminology
    - Excellent interpersonal skills; a team player
    - Basic project management and organizational skills
    - Ability to prioritize and manage multiple projects
    - Attention to detail related to consistency, grammar, syntax, and scientific accuracy
    - Basic computer skills related to word processing, templates, table/figure creation, and literature searches

    Minimum Requirements 

    -Ph.D. (or equivalent degree) and 0 – 3 years of relevant work experience, or
    - M.S. (or equivalent degree) and 1 – 4 years of relevant work experience, or
    - B.S. (or equivalent degree) and 3 – 6 years of relevant work experience

     


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    Research Associate/Senior Research Associate, Protein Engineering

     

    The successful candidate will work with the Equipoise Therapeutics team to develop novel therapies that stimulate immune responses against both solid and hematologic cancers.

     

    Responsibilities:

    • Expression and purification of recombinant proteins
    • Engineer (design and subclone) new proteins products
    • Perform biochemical, cell and molecular biology experiments
    • Culture of cancer cell lines and immune cells
    • Plan experiments and coordinate with others when needed
    • Generate, analyze, interpret, and present experimental data
    • Develop new assays and troubleshoot when needed
    • Manage daily work flow independently and seek advice when appropriate
    • Stay attentive but flexible with deadlines
    • Work collaboratively with the Equipoise team

     

    Qualifications:

    • B.S. or M.S. degree in biochemistry, molecular biology, or relevant field
    • 3+ years of relevant research experience, industry experience strongly preferred
    • Strong background in biochemistry, cell and molecular biology, or cancer biology
    • Demonstrated mastery of protein expression, purification, and assay
    • Experience with basic cell and molecular biology techniques and cell culture
    • Proficiency with data analysis methods and software
    • Strong organizational and record keeping skills
    • Ability to multi-task with a high attention to detail
    • Ability to work in concert with a team as well as independently
    • Excellent written and verbal communication
    • Self-motivated, conscientious, and enthusiastic about curing cancer

     

    Equipoise Therapeutics is a discovery-stage company that aims to stimulate immune responses against cancer. We are developing novel first-in-class therapeutics targeted at natural killer cells as well as other cells of the innate immune system. These therapies are designed to counterbalance immune suppressive factors present in the tumor microenvironment and mobilize anti-cancer immune responses. Our molecules are expected to be potent as single agents as well as in treatment combinations with existing cancer immunotherapies. Our scientific founders are major figures in cancer biology and immunology and have launched Equipoise to effectively harness the power of the immune system to provide durable cancer treatments for patients.

     

    Please send your cover letter and resume to: join@equipoisetherapeutics.com.

    Updated December 8, 2015.

     

     

    Equipoise Therapeutics | One Kendall Square | Bldg 200, Suite 2203 | Cambridge, MA 02139 | equipoisetx.com


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  • 12/10/15--23:08: Medical Coder
  • CLIENT: BIOTECH COMPANY

    Job Summary 
    The Medical Coder is responsible for conducting centralized medical coding activities using agEncoder as part of the ARISg Safety database. 

    Principal Accountabilities 

    1. Perform medical coding (WHO Drug Dictionary Enhanced and MedDRA) activities according to the coding schedule. Maintain optimal communication with Safety staff and Safety vendors for all post marketing cases managed by Safety as per Biogen and/or applicable coding conventions 
    2. Support senior coders in coding related activities and supversioning activities 
    3. Contribute to the development of coding conventions and coding process 

     

    ADDITIONAL INFO:

    Safety experience coding safety cases. Clinical trial experience in coding 

    2-5 years medical coding using the MedDRA and WHO Drug dictionaries as well as the structure and function of systems used to perform coding. 

    Possesses a degree in nursing, pharmacy or other related medical field.


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  • 12/10/15--23:30: Business Analyst
  • Job Description: Intern

     We are seeking an Intern to join our team for the academic year.  In this role, your primary responsibility will be to conduct business and scientific due diligence and write summary slides/reports on your findings.  In this role you will report to the President and Chief Scientific Officer.

     Essential Duties:

     - Conduct scientific and competitive market research and write reports on potential clinical indications, scientific approaches, and competing drugs on the market

     - Evaluate market and business opportunities and write reports

     - Conduct literature searches, read clinical & scientific papers and summarize results

     - Conduct patent searches and write reports

     - Maintain databases of competitive intelligence.

     - Prepare presentations

     - Maintain project schedules

      -Maintain and organize files

      -Perform clerical and other office functions as needed

       
    Working hours: Flexible (minimum 10hrs/week)

    Credentials/Requirements:


       - Enrolled in a 4-year undergraduate program with at least two years of study in a science or business major

       - Friendly, professional with excellent oral and written communication skills


       - Organized, proactive self-starter

       - Proficiency with business software

       This is an excellent opportunity to contribute to our team and expand your knowledge base.    

     About Corbus:

    Corbus Pharmaceuticals, Inc. is a clinical stage biopharmaceutical company located in Norwood, MA, focused on the development and commercialization of novel therapeutics to treat rare (“orphan”), life-threating inflammatory-fibrotic diseases with clear unmet medical needs. Our lead product Resunab™ is a novel oral anti-inflammatory drug that is currently in Phase II clinical trials for the treatment of cystic fibrosis, scleroderma, and dermatomyositis.  www.corbuspharma.com

     

     

     


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    Toxikon Corporation, originally founded in 1977, is a Contract Research and Testing company with laboratories in Bedford, MA and Belgium. Our mission is to provide quality pre-clinical research services to Pharmaceutical, Medical Device, and Biotech industries.

    We are seeking an experienced Outside Sales professional to market Toxikon's preclinical testing services in assigned territories.  The Business Development Manger will identify, analyze, contact, and provide testing service proposals to new customers.  Will generate leads, prepare quotes, request protocols, and work with customer service and laboratory staff.

    Minimum Qualifications

    • Degree in life sciences, chemistry or biology
    • Strong understanding of the testing and service industry, including regulatory agencies, as well as the ability to converse with clients on testing & service needs (for pharmaceutical, biotech, and medical device companies).
    • Prior CRO and/or lab experience preferred.
    • Experience with cold calls and client development required.
    • Proven ability to generate new accounts and meet territory account revenue targets.
    • Must be self-motivated and a strong team player.
    • Excellent communication, presentation, organizational, and computer skills required.
    • The ability to handle several projects concurrently is necessary.
    • Must travel at least 60% for face to face client meetings.

    We are an ISO certified environment, and studies are conducted under numerous guidelines, protocols, and Standard Operating Procedures. Business Development Representatives will be required to learn about Toxikon services and systems.  Must also adhere to Toxikon's Standard Operating Procedures, as well as other regulatory guidelines.

    To apply to this position go to: https://workforcenow.adp.com/jobs/apply/posting.html?client=toxcorp&jobId=11519&lang=en_US&source=CC272256

    For additional information about Toxikon, please visit www.toxikon.com.

    Toxikon offers a comprehensive benefits program including: paid vacation, sick time, 401(k) plan with company match, medical, dental, vision care, life insurance, short and long-term disability insurances, flexible spending accounts, employee assistance program, employee referral bonus, discount programs and more. 


    Toxikon is an equal opportunity employer.  As an equal opportunity employer we do not unlawfully discriminate against any applicant because of race, sex, gender, ethnicity, religion, creed, age, color, military/veteran status, genetic condition or information, Family and Medical Leave entitlement, sexual orientation, gender identity, national origin, ancestry, marital status, qualified physical or mental disability, transgender status, or any other legally protected class in accordance with federal, state and local laws. 


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  • 12/11/15--00:07: Facilities Manager
  • Toxikon Corporation, originally founded in 1977, is a Contract Research and Testing company with laboratories in Bedford, MA and Belgium. Our mission is to provide quality pre-clinical research services to Pharmaceutical, Medical Device, and Biotech industries.

    Job Summary

    As the Facilities Manager, candidates will operate, inspect, maintain and repair all HVAC, mechanical, electrical and plumbing equipment and systems in the facility to obtain most efficient operating results and life expectancy.  This individual will assure that equipment is being maintained in an energy efficient and safe manner and down time is reduced to a minimum by anticipation of necessary repairs.  Performs inspections and repairs to the facility interior and exterior areas including walls and flooring, installed fixtures, roofing systems, lighting, etc.

    Duties and Responsibilities

    • Performs and supervises ongoing preventive maintenance and repair work orders by the facility staff on mechanical, electrical, lighting and other installed systems, equipment and other components.
    • Schedule and supervise the maintenance operation and repair of all HVAC systems and associated equipment, electrical distribution equipment, plumbing systems, building interior/exterior repairs and related grounds.
    • Perform facility inspections as required by monthly work orders.
    • Respond effectively to all emergencies.
    • Insure facility safety procedures, maintaining good housekeeping and safety of work areas.  Recognize danger and safety hazards and propose methods to eliminate them.
    • Maintain compliance to all State, Federal and Agency codes.
    • Must be willing and able to support after-hours building related activity as required and respond to emergency calls and/or organize back-up 24 hour coverage.
    • Manage day-to-day financial including budgeting and reporting. 
    • Perform other operational tasks as may be typically expected of the Facilities Manager.

    Minimum Requirements

    • Associates Degree in Facility Maintenance or Related Field.
    • Must possess and maintain a valid State driver’s license.
    • Universal CFC recovery certification.
    • Minimum of 5 years of technical experience in all aspects of building engineering with a strong background in technical aspects of HVAC equipment and systems, plumbing, electrical, equipment repair and maintenance, and overall system design and application.
    • Experience in Emergency Procedures waste water treatment operation helpful.
    • Customer focused attitude. 
    • Experience with laboratory equipment installation and maintenance, water systems, process water and acid waste systems. 
    • Ability to prioritize and work on several projects concurrently. 
    • Must be dependable and work independently. 
    • Ability to work with vendors and review work for contractors.
    • Knowledge of Microsoft Office Word, Excel & Outlook. 

    Physical Requirements

    • Physical demands required include the ability to sit, walk, climb up and down stairs, use hands and fingers and reach with hands and arms. 
    • Required to occasionally lift up to 60 lbs.

    To apply to this position go to: https://workforcenow.adp.com/jobs/apply/posting.html?client=toxcorp&jobId=12641&lang=en_US&source=CC2

    For additional information about Toxikon go to www.toxikon.com.

    Toxikon offers a comprehensive benefits program including: paid vacation, sick and personal time, 401(k) plan with company match, medical, dental, vision care, life insurance, short and long-term disability insurances, flexible spending accounts, employee assistance program, employee referral bonus, discount programs and more.

    Toxikon is an equal opportunity employer.  As an equal opportunity employer we do not unlawfully discriminate against any applicant because of race, sex, gender, ethnicity, religion, creed, age, color, military/veteran status, genetic condition or information, Family and Medical Leave entitlement, sexual orientation, gender identity, national origin, ancestry, marital status, qualified physical or mental disability, transgender status, or any other legally protected class in accordance with federal, state and local laws.

     


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  • 12/11/15--00:11: Formulations Chemist
  • Toxikon Corporation, originally founded in 1977, is a Contract Research and Testing company with laboratories in Bedford, MA and Belgium.  Our mission is to provide quality pre-clinical research services to Pharmaceutical, Medical Device, and Biotech industries.

    Job Summary

    Seeking qualified individual with 2-5 years of formulations and dose preparation skills to maintain a formulations laboratory in a preclinical testing facility. Strong math and science skills and the ability to maintain a fully compliant laboratory environment is essential. Successful candidate will work with Department Heads and Study Directors to provide all support required for their studies.

    Essential Duties - Pharmacy/Log-In

    • Assist with picking up and maintaining custody of all incoming materials from clients from Shipping/Receiving.
    • Generate tracking forms and study related documents (Sponsor communications, protocols, requisition form) for all relevant studies.
    • Properly store and track all materials (including dosing formulations and other study related materials) maintained in the Pharmacy.
    • Track removal and return of all test materials.
    • Reconcile and account for all materials appropriately at the end of a study as directed by the Sponsor or Study Director.
    • Maintain up to date accurate records for materials that have entered the pharmacy and records of use and log out of materials for both formulations, dosing and other usage.
    • Work with Study Directors to accurately determine if additional materials are needed.
    • Work with Health and Safety for proper storage, formulation and use of any potentially hazardous materials.

    Essential Duties - Formulations

    • Responsible for preparation and processing of formulations per instructions in protocols and/or SOPs.
    • Generate and maintain records on all dispensation, preparation, routing and custody of samples.
    • Maintain active inventory of test article, control articles, vehicles, carriers, etc.
    • Assist in the characterization and verification procedures of formulations with the Analytical Chemistry department.
    • Maintain Formulations Laboratory and instruments per Equipment Usage procedures and interface with Metrology and Validation services as required.
    • Maintain all equipment records and submit monthly performance verification records for the Formulations Laboratory.
    • Maintain all required records to quality standards and completeness requirements.
    • Assist in managing technical and regulatory site visits to the laboratory and interface with QA and RA on all vendor/regulatory audits.

    Essential Duties - Study Support

    • Maintain and monitor schedule of performance, flow of information and reporting of studies.  Ensure that reports are reported timely and all special testing preparations are properly handled
    • Participate in the daily scheduling, forecasting and needs of the Formulation Laboratory.
    • Assist project management and other sales staff with quotation/pricing information.
    • Maintain laboratory accreditation and registrations as required.
    • Interact with clients as required.
    • Maintain conformance with Toxikon’s quality mission statement, goals and values. Enforce and maintain compliance with Toxikon’s Quality System ISO 17025. 

    Minimum Requirements

    • Bachelor’s Degree in chemistry or pharmaceutical sciences.
    • Experience in the preparation, processing and testing of dose formulations (sterile or non-sterile) for pre-clinical pharmaceutical studies.
    • Must have strong organizational skills and ability to multi-task in a fast paced environment.

    To apply to this position go to: https://workforcenow.adp.com/jobs/apply/posting.html?client=toxcorp&jobId=12241&lang=en_US&source=CC2 

    Toxikon offers a comprehensive benefits program including: paid vacation, sick and personal time, 401(k) plan with company match, medical, dental, vision care, life insurance, short and long-term disability insurances, flexible spending accounts, employee assistance program, employee referral bonus, discount programs and more.

    Toxikon is an equal opportunity employer.  As an equal opportunity employer we do not unlawfully discriminate against any applicant because of race, sex, gender, ethnicity, religion, creed, age, color, military/veteran status, genetic condition or information, Family and Medical Leave entitlement, sexual orientation, gender identity, national origin, ancestry, marital status, qualified physical or mental disability, transgender status, or any other legally protected class in accordance with federal, state and local laws.


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    Sr. Research Associate - Immunology will test protein therapeutics in transplantable tumor models.

     

    For details visit: http://www.cwsciences.com/Current-Openings/Sr-Research-Associate--Immunology

     

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


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    Sr. Research Associate - Immunology will test protein therapeutics in transplantable tumor models.

     

    For details visit: http://www.cwsciences.com/Current-Openings/Sr-Research-Associate--Immunology

     

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


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    Candidate will express, purify, and characterize monoclonal antibodies and other therapeutic proteins, and help select the best drug candidate

    For details visit:

    http://www.cwsciences.com/Current-Openings/Associate-Scientist--Protein-Analytics

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.

    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


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    Downstream Process Development Associate will support the development of biologics.

    For details visit:

    http://www.cwsciences.com/Current-Openings/Downstream-Process-Development-Associate

     

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


    0 0

    GENERAL SUMMARY/OVERVIEW STATEMENT: 

    Under the direction of the Director of the BWH Center for Comparative Medicine, incumbent has overall responsibility for overseeing and managing daily operations and activities involved with the provision of animal husbandry, vivarium operation, procurement, and cagewash at all BWH CCM facilities. The individual will ensure all aspects of operation of the vivarium and the husbandry/animal care conducted within the facilities meets federal and state regulations, AAALAC accreditation standards, and research support needs for the investigative research staff. This position will manage contract staff and serve as a liaison between the contract vendor and BWH.    

    PRINCIPAL DUTIES AND RESPONSIBILITIES: 

    1.Actively provides administrative and managerial support to BWH CCM Director by developing and collaboratively establishing process improvement to meet the business needs of the organization and/or enhance the institutional animal care and use program. 2.Oversees and directs facility supervisors and the daily operations and management of all BWH CCM facilities and a variety of laboratory animal species.  3.Ensures fiscal responsibility in the daily operations of the animal facilities and overall animal research program. Generates budgets relevant to his/her area of oversight. 4.Performs administrative duties associated with running a facility: tracking of operating revenues and expenses, capital equipment needs, projects, capacity, and other operational metrics, including oversight of billing and establishing per diems. 5.Manages the daily operations of the BWH CCM facilities, including personnel and process management, during a supervisor absence. 6.Collaborate with internal hospital departments/research labs, especially key stakeholders in Security, Occupational Health, IACUC, Finance, Environmental Health, and the IBC, as well as external stakeholders (HMS, etc.) 7.Serves as the primary point of contact with outside equipment vendors and service contractors.  8.Ensures accurate and appropriate reporting to oversight committees, as necessary. 9.Take a leading role in opening of a new vivarium, including commissioning, testing new equipment and technology, stocking facility, etc. 10.Assure facilities and operations are maintained at a high level of animal care, meeting or exceeding all federal, state and local regulatory requirements and AAALAC standards. 11.Promotes a team culture and leads continuous improvement initiatives within the facility and throughout the department. Manages team-based work assignments, facilitates workplace organization improvements, and structured team problem solving.  12.Assist researchers in project feasibility and complex facility needs, as required. 13.Champions a customer-centric environment throughout the facility. Addresses and resolves problems or questions from investigative staff concerning the facility or animal care in general. 14.Ensures consistency and integration across facilities, in part by, writing/reviewing SOPs for facilities. Ensures efficiency, compliance and feasibility of SOPs in conjunction with contract staffing vendor. 15.Along with the Director, BWH CCM, develops and oversees the training program for husbandry staff and researchers. 16.Manages transportation and transfer of animals between facilities and among collaborating institutions. 17.Stays current on advancing standards of animal care and related regulatory requirements.  

    QUALIFICATIONS: 

    1.Bachelor’s Degree, with major study in a basic or applied science OR equivalent combination of training, formal education (such as an Associate’s Degree in Veterinary Technology) and/or research, training or laboratory operations experience.  2.5-6 years of experience in research animal facility management. 3.Certification by the American Association for Laboratory Animal Science (AALAS) at the Laboratory Animal Technologist (LATG) level. 4.Certification by the American Association for Laboratory Animal Science (AALAS) at the Certified Manager Animal Resources (CMAR) level or ability to obtain CMAR prior to start.    

    SKILLS/ABILITIES/COMPETENCIES REQUIRED: 

    1.Strong customer service skills and ability to navigate complex political environments. 2.Experience with Microsoft Word, Excel, and other Microsoft Office applications.  3.Experience with electronic databases and reporting. 4.Experience handling and providing husbandry for a variety of animal species and training others on the same. 5.Ability to make appropriate, sustainable decisions regarding daily facility operations and to address unique situations that arise within the animal research facilities. 6.Has a customer-focused attitude and enjoys working with similarly dedicated persons in a team fashion within a high-energy research environment. 7.Management skills appropriate for overseeing a large, complex program. 8.Ability and willingness to learn RFID and bar code software used for census, and other technologies as developed.    

    WORKING CONDITIONS: 

    The animal facility has a variety of environmental conditions.  Specifically, employees may be exposed to noise, dust, chemicals, extreme heat, and animal waste products. The duration of exposure to any of the above is dependent on the assigned duties. Some aspects of this position may expose the incumbent to potential zoonotic diseases.  Appropriate protective clothing and equipment may be required and will be provided when required, accompanied by appropriate training; Long periods of standing; Must be able to lift 50 pounds.     

    SUPERVISORY RESPONSIBILITY: 

    Directly supervises research animal technician staff and team leaders. Exact number of FTEs not yet determined. All animal tech staff will be provided by an organization contracted to help manage the facility.  Contract still pending.     

    FISCAL RESPONSIBILITY: 

    1.Budgetary responsibility, including planning yearly budget and monitoring actual performance against budget. 2.Manage those individuals responsible for procurement of supplies and animals. 3.Oversee service contracts for all animal facilities. 4.Expected to identify ways to perform required duties in the most economical way possible and make recommendations for cost and resource saving improvements.    

    Brigham and Women’s Hospital is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, sexual orientation, protected veteran status, or on the basis of disability. 


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    Description:

    Sr. Research Associate will assist the development of therapeutics in the field of cancer immunology.

    For details visit:  http://www.cwsciences.com/Current-Openings/Sr-Research-Associate--Cancer-Immunology

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com

     


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    Research Associate - Molecular Biology will join a group dedicated to the discovery of therapeutics for neurological diseases.

    For details visit: http://www.cwsciences.com/Current-Openings/Research-Associate--Molecular-Biology

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com

     

     


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  • 12/11/15--00:26: Analytical Chemist - Protein
  • Analytical Chemist will characterize and purify proteins in support of drug development activities.

    For details visit: http://www.cwsciences.com/Current-Openings/Analytical-Chemist--Protein

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


     


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    Beryllium Discovery Corp. provides innovative solutions and insightful strategies in structural and cell biology in order to advance scientific discovery and enable our customers to perform novel drug discovery.  Our teams support leading pharmaceutical, biotechnology and research institutions.

     

    Our Bedford, MA facility has an opening for a talented NMR spectroscopist, with a broad range of experience to join the Biophysics group as part of the drug discovery program.  This Senior Research Scientist will independently execute NMR-based research programs, conduct biophysical scientific studies and provide support for these efforts.

     

    The Senior Research Scientist will be involved in the daily operation of the NMR lab and be responsible for coordinating research efforts for Beryllium and its clients.  The individual will be expected to evaluate new techniques and implement novel biophysical assays while maintaining a strong emphasis on delivering critical project needs.  There will be close collaborations with structural biologists and functional biologists where the individual will serve as a representative for fragment-based lead discovery and/or biophysical methods within multi-disciplinary projects.  The candidate should have a solid understanding of nucleic acid NMR research and in particular have experience working with RNA.  In addition, the candidate should have an understanding of the progression of small molecule drug discovery programs from early stage lead finding, lead validation, lead optimization to candidate selection.

     

    Responsibilities:

    • Management of Bruker instrument with HCN cryoprobe and SampleJet autosampler;
    • Conduct fragment/ligand-based screens and SAR to early stage research and discovery programs;
    • Conduct Protein-based screens and SAR to early stage research and discovery programs;
    • Management of research projects in a team setting and communication of research results to Project Managers and Beryllium clients;
    • Small molecule structure determination, QA/QC and data management for small molecule ligand collection;
    • Management of libraries for high throughput fragment screening;
    • Implementation of state-of-the-art NMR methods and strategies with a willingness to develop new techniques/protocols as needed in support of client solutions;
    • Maintain state-of-the art knowledge and contribute to the field with scientific publications and conference presentations.

     

    Experience:

    • PhD in a relevant scientific discipline (Physical/Biophysical/Organic Chemistry/Structural Biology);
    • Experience in NMR of small molecules, nucleic acids, peptides and proteins, with an emphasis in fragment based drug discovery towards RNA targets;
    • Expert knowledge and application of current NMR screening techniques, small molecule NMR and QC, library design, automation and analysis of high-throughput NMR data sets;
    • Proficiency with NMR software applications;
    • Strong, communication and interpersonal skills essential for building and developing strong scientific collaborations as demonstrated through peer-reviewed scientific publications and successful collaborative research endeavors.

     

    We offer a competitive compensation and benefits package including 401k, health benefits and vacation.  Qualified candidates should send a resume and cover letter. 

     

    As an equal opportunity employer, Beryllium Discovery Corp. will consider all qualified applications for employment.  EOE AA M/F/Vet/Disability.

     

     


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