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Career postings for the Massachusetts Biotechnology Council

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  • 12/22/15--23:23: Research Specialist
  • GENERAL SUMMARY/OVERVIEW STATEMENT:

    The mission of the Center for Clinical Investigation (CCI) is to strengthen the culture for clinical research at the Brigham and Women’s Hospital, by building services helpful to clinical investigators and facilitating the success of individual investigators. Working within the CCI the statistician will support research projects conducted by investigators at Brigham and Women’s Hospital, as well as external academic research institutions and private companies. Qualified candidates will have advanced formal training in statistics or biostatistics including design and analysis of observational and experimental studies, and strong statistical computing skills

    PRINCIPAL DUTIES AND RESPONSIBILITIES:

    1.Possess a solid understanding of the purpose, objectives and goals of each trial. 2.Collaborate with investigators to develop and perform statistical analyses (including planning, programming, analysis, interpretation and writing of results) for investigational protocols, subgroup and post-hoc projects and registry databases ending with preparation of manuscripts, abstracts and presentations at scientific meetings. 3.Assists in the development of randomization schedule, sample size and power calculations. 4.Responsible for assuring that data for statistical analyses are accurate. 5.Determine and/or verify correct statistical testing to be performed in each analysis request. 6.Rearranges data in a format that allows for accurate use as well as possible integration and pooling across trials.  1.Collaborates with faculty  on analytical objectives 7.Maintain department service standards as outlined in the BWH Code of Conduct 8.Performs other duties as required and as appropriate.   9.Effectively mentors non-statistical peers with regard to basic statistical methodology 10.Can clearly communicate basic statistical concepts to other scientists and nonscientists 11.Draft methods sections in manuscripts for publication 12.Provide biostatistics consultations

    QUALIFICATIONS:

    1.MPH or MS in biostatistics and/or other health sciences related field required. 2.5 years of direct research experience 3.Working knowledge of SAS, STATA, and R programming as well as advanced mastery of statistical analyses. 4.Must be deadline oriented. 5.Has thorough understanding of analysis, coding, testing and project methodologies.

    SKILLS/ABILITIES/COMPETENCIES REQUIRED:

    1.Demonstrated statistical/analytical and reasoning skills to perform high level problem solving. 2.Ability to work independently as well as part of a team 3.Ability to prioritize assignments, multi-task, make decisions based upon sound principles, and independently problem solve. 4.Detail and process oriented 5.Ability to manage multiple projects simultaneously, including both long-term and short-term projects 6.Excellent communication skills-both oral and written. 7.Ability to develop novel ways to coordinate, manage and report data if required by new trials 8.High level of confidentiality must be maintained. 9.Demonstrated sound independent judgment and competencies in clinical research.

    Brigham and Women’s Hospital is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, sexual orientation, protected veteran status, or on the basis of disability.

     

    If you are interested in the position, please apply to Job ID# 3008841 with the link below:

    http://www.brighamandwomens.org/About_BWH/Careers/external-candidate-job-listings.aspx?sub=0


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    New England Biolabs is inviting applicants for the position of Applications and Product Development Scientist.  The successful candidate will work with a diverse team of scientists to develop novel RNA and genome editing products including RNA modification and analysis reagents, RNA synthesis products, and products to support the emerging genome editing field.

    Primary Responsibilities:

    • Assist with development of products for the RNA product portfolio this includes RNA synthesis, modification and analysis and genome editing workflows.
    • Support all stages of new products from development to product release.
    • Assay optimization and quality control development.
    • Work with the Marketing department to create technical literature to accompany the RNA and genome editing product lines.

    Qualifications and Experience:

    • Ph.D. in a biochemistry, molecular biology or related field.
    • Minimum of 2 years’ experience in a life science role.
    • Strong molecular biology background with focus on RNA modifications and analysis including RNA synthesis.
    • Experience with genome editing technology.
    • Strong molecular biology bench skills (DNA/RNA).
    • Experience with Protein expression and purification by FPLC preferred.
    • Excellent verbal and written communication skills.
    • Goal oriented team player with a strong work ethic.

     

      New England Biolabs is an Equal Opportunity/ Affirmative Action Employer of Minorities, Females, Disabled and Protected Veterans 

    Candidates may apply online at www.neb.com or by accessing the following link: Applications and Product Development Scientist

     

     


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    The DNA Enzymes Division of New England Biolabs (NEB) invites applicants for the position of Postdoctoral Fellow. Projects will be part of a research program aimed at studying and reconstituting replication systems using genetic, biochemical and single molecule approaches.

    Required Qualifications:

    • Ph.D. in biochemistry, bioengineering, molecular biology or related field.
    • Technical expertise in enzymology.
    • Technical expertise in multi-component enzyme systems.
    • Excellent presentation and writing ability.
    • Publication of original scientific work in high-quality journals.

    Preferred Qualifications:

    • Have "good hand" with proven bench skills.
    • Strong scientific curiosity, integrity, creativity and self-motivation.
    • Experience in assay development.
    • Next generation sequencing and data analysis.

    This position offers exciting opportunities for broad research training, collaboration with academic and industrial institutions, publishing in peer-reviewed journals and participation in national and international conferences.

     

    New England Biolabs is an Equal Opportunity/ Affirmative Action Employer of Minorities, Females, Disabled and Protected Veterans

    Qualified candidates may apply online at www.neb.com or by clicking on the following link: Postdoctal Fellowship, DNA Enzymes

     


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    Education & Experience Requirements:
    * High School diploma or GED required
    * A minimum of 12 years of office administration experience with prior experience supporting executives required

    Key Skills, Abilities, and Competencies:
    * Extensive working knowledge of SAP, MS Word, Excel & PowerPoint.
    * Advanced knowledge of MS Outlook is essential.
    * Experience with expense reporting systems/software.
    * Strong interpersonal skills; position continually requires demonstrated poise, tact and diplomacy.
    * Must be able to interact and communicate effectively with individuals at all levels of the organization.
    * Requires strong attention to detail in composing and proofing materials, establishing priorities, scheduling and meeting deadlines.
    * Must be able to work in a fast paced environment with demonstrated ability to simultaneously manage multiple competing tasks and demands.
    * Must be flexible in handling multiple tasks of a different nature and have the ability to prioritize efficiently.
    * Must be able to handle confidential information and issues effectively and without breach of confidentiality

    Other Job Requirements:
    * Ability to hear and speak to employees/management and outside business associates on the phone and in person
    * Ability to sit for long hours at a time
    * Ability to see the letters and numbers on a personal computer screen and on memoranda, reports and other documents (near vision)
    * Requires moderate right and left hand coordination for the use of the personal computer
    * Must maintain a professional image/demeanor
    * Fluent in English
    * Domestic travel

    About Shire:
    Shire's Brave culture offers employees with diverse backgrounds the opportunity to enable those with life altering conditions to lead better lives. Shire is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by applicable law. US Applicants who require accommodation in the job application process may contact 484-595-8400.

    Application URL:http://www.aplitrak.com/?adid=c21vdXNzZWF1LjIzNTU1LjMxNjdAc2hpcmUuYXBsaXRyYWsuY29t


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  • 12/23/15--23:23: QC Analytical Scientist II
  • Org Marketing Statement
    A career at Pfizer offers opportunity, ownership and impact.

    All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

    Role Description
    The Quality Control Analytical group is seeking a highly motivated candidate to support analytical testing activities for multiple products at the Andover site. The work includes various HPLC, UV spectrophotometry, and ELISA methods. The candidate will also be responsible for supporting troubleshooting and method improvements at the site.

    Responsibilities
    Key responsibilities:
    The qualified candidate will work in a cGMP Quality Control Analytical lab.

    Responsibilities include:
    * Perform Analytical testing of in-process, drug substance, and drug product samples.
    * Identify basic technical issues, atypical or out-of-specifications test results, instrument
    malfunctions and methodology problems and participates in the investigation to resolve and correct.
    * Participates in continuous improvement culture within labs. Utilizes continuous improvement
    tools such as DMAIC.
    * Maintain all related data and records in compliance with cGMPs and quality procedures.
    * Prepares and record buffers and reagents, etc., and maintain work area in a neat and orderly manner.

    Qualifications
    * B.S. in Biology, Chemistry or related scientific discipline with a minimum of 4 years of related laboratory experience. M.S. with a minimum of 2 years of related laboratory experience.
    * Lab Experience in: HPLC (Peptide map and Oligosaccharide), ELISA, iCE, Bioassay, CE, and UV
    * Strong oral and written communication skills , technical writing skills preferred
    * Knowledge and understanding of cGMP and industry standards
    * Proficiency with computer systems (Microsoft Office applications, LIMS, etc.).
    * Experience working in cGMP USP/EP/JP, regulatory environment.

    PHYSICAL/MENTAL REQUIREMENTS:
    Normal lifting, sitting, standing and walking requirements to facilitate testing in a laboratory environment. Position is first shift Monday through Friday. Some off hour (night/weekend/holiday) support may be required to support staff and operations.

    EEO & Employment Eligibility
    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

    Application URL:http://www.aplitrak.com/?adid=SmltLlRhdm9saWVyaS41Mjg0Mi4zMTY3QHBmaXplci5hcGxpdHJhay5jb20


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  • 12/24/15--03:38: Desktop Support Specialist
  • Broad IT provides-and this role directly coordinates-end-user support of more than 2500 laptops, desktop systems (Windows and Mac) across Broad several buildings as well as telephony, printing, and conference room A/V, and a walk-up service desk. The desktop support organization comprises 8-10 Desktop Support Specialists and the Service Desk Coordinator under the supervision of the Manager for the Service Desk.

    The Desktop Support Specialist I role is responsible for first line support for the Broad community either by email, phone, remote or in-person. The position requires a strong focus on customer service and an ability to work efficiently and effectively in a fast pace environment. The work performed by a DTS I varies from day to day and as such the individual will need to be able to multi-task often to ensure the work gets processed and the incident closure rate remains high.

    PRINCIPAL DUTIES AND RESPONSIBILITIES:
    - Imaging, deploying and reclaiming computing equipment to end users on a timely basis.
    - Accurately record and update incidents on our Service Now instance in a timely manner.
    - Assist in developing, documenting new procedures as well as suggest process improvements-Respond to and update incidents promptly
    - Other duties as assigned by the Service Desk Manager

    MINIMUM QUALIFICATIONS:
    - Degree in Computer Science or other technical discipline with in-depth understanding of modern computing technology or equivalent training or experience0-1 years experience-Strong problem solving ability-Be able to follow established procedures-Previous experience supporting Windows, MacOS, Dell and Apple hardware in a high paced real-time work environment

    Preferred: Microsoft Certified Professional, Apple Certified Macintosh Technician Certification, MacOS 10.9 Certification, Comptia A+, HDI Service Desk Analyst or HDI Desktop Support Technician-Previous customer service experience is strongly desired

    WORKING CONDITIONS:
    - Normal office conditions
    - Ability to lift up to 50lb
    - Working hours are 9:00 am - 5:00 pm, may be asked to come in earlier or stay later as needed

    The Broad Institute will not offer visa sponsorship for this opportunity.EOE/Minorities/Females/Protected Veterans/Disabilities

    To apply for this position, please CLICK HERE


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  • 12/24/15--03:48: Network Engineer
  • Senior member of the team that operates Broad data communication systems and infrastructure. Lead the planning, design, implementation and maintenance efforts for network hardware and software infrastructure in order to provide fast, agile and reliable connectivity that addresses institutional infrastructure requirements.

    Responsibilities:
    Architect, implement and test new networking solutions that address current and future institutional needs.Contribute to design, implementation, monitoring and maintenance of the Broad network.Monitor the networking environment and improve performance, reliability and availability; diagnose failures and resolve uncovered issues.Plan and participate in the installation and configuration of network hardware.Maintain documentation for network infrastructure.

    Oversee issue tracking tickets relating to network infrastructure and respond as necessary; assist junior team members in addressing tickets.Act as technical lead and manage network projects, as assigned by IT leadership.Participate in budget planning for equipment and software.Act as a mentor to other team members.Manage existing vendor relationships and identify new technologies that enhance the network infrastructure.4+ years related networking experience, additional IT experience a plus.Strong knowledge of core network fundamentals, including firewalls,switching and routing.

    Working knowledge of the following platforms:
    Cisco ASA, Cisco Nexus, Cisco ASR, Cisco Catalyst, Brocade VDX, Palo Alto IPS; willingness to investigate and learn new technologies as required.
    Knowledge of data center electrical standards and related calculations;
    knowledge of cooling and air handling a plus.Bachelor degree in computer science or other technical discipline or equivalent level of experience.Cisco CCNP certification or equivalent knowledge.Ability to climb and work on a ladder up to 4 feet. Ability to lift and carry up to 40 lbs.Ability to use manual and power tools, including screwdrivers, wrenches and drills.Share on-­‐call support for nights and weekends with other members of the network operations team.The Broad Institute will not offer visa sponsorship for this opportunity.
    EOE / Minorities / Females / Protected Veterans / Disabilities

    To apply for this position, please CLICK HERE


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    Acorda Therapeutics, Inc. is a world leading pharmaceutical company focused on developing therapies that improve lives of people with neurological disorders. Acorda has a manufacturing facility in Chelsea.  The lead product in this facility is for the treatment of Parkinson’s disease. This product is in phase III of development and could profoundly increase the ability for many Parkinson’s patients to live relatively normal lives.

    The Quality Control Supervisor (or Quality Control  Analyst IV ) is responsible for executing QC testing and related analytical activities supporting product development, release and stability. This individual may have responsiblity to oversee 1 - 3 Analysts.  This individual conducts routine and non-routine chemical and physical analyses of raw materials, in-process materials and drug products according to standard operating procedures. The Quality Control Analyst IV compiles data for documentation of test procedures that may include stability program testing and formulation studies, participates in the preparation of investigations, summaries and reports, and reviews data obtained for compliance to specifications and reports out-of-trend and/or out-of-specification results. The Quality Control Analyst IV revises and updates standard operating procedures as needed. 

    *Essential Duties and Responsibilities include the following. Other duties may be assigned.

    • Operates analytical instrumentation including HPLC, UPLC, GC, UV-vis, FTIR, laser diffraction, KF.
    • Statistically and critically analyzes data for trending and reporting into regulatory filings. 
    • Participates in Laboratory and/or Quality Investigations.
    • Monitors equipment and instrumentation used on a daily basis to ensure proper operation and calibration.
    • Participates in the construction and/or revision of SOPs. 
    • Assists in the writing and updating of analytical test procedures, protocol, log books and checklists. 
    • Responsible for identifying, alerting and proposing solutions to issues on instruments and/or test executions; leads and implements recommended solutions and/or corrective actions.
    • Independently organizes work flows to accomplish objectives, provides guidance and support to colleagues as needed, promotes new policies and programs tactfully and authentically, and may author/document performance reviews and/or evaluations. 

    Education and/or Experience:

    • Bachelor’s Degree in Physical or Chemical Sciences (life sciences) required.
    • Minimum of 5-8 years of experience in a cGMP regulated environment required.
    • Must have experience with HPLC
    • Experience in MDI/DPI analytical test methods (i.e. Andersen Cascade Impactor and Emitted Dose techniques) preferred.
    • Experience supervising, training or mentoring analysts is preferred.
    • .Chromatography skills using Empower and/or ChemStation required

    Supervisory Responsibilities: This position may supervise a small group of QC Analysts 

       Qualifications:

    • Extensive experience with executing QC test methods, generating associated data packages, auditing data packages generated by others, troubleshooting instrumentation, trending data and statistical analyses required.
    • Demonstrated ability to lead projects and/or teams independently

    Please visit our website www.acorda.com/careers  to learn more about Acorda Therapeutics and this opportunity.  If qualified and interested,  Please submit your resume.  Thank you for your consideration!


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  • 12/24/15--09:25: Drug Safety Physician
  • Position Description:

    The Drug Safety Physician is responsible for safety surveillance of Ironwood products. This implies medical assessment of adverse event reports, detecting and assessing safety signals and proposing risk mitigating activities. With that aim, the Drug Safety Physician represents the medical safety function in relevant business processes, project teams and committees, both in clinical development and in the postmarketing space, to ensure consistency of safety focus, methods and communications. The role of the Drug Safety Physician is a global one, and covers all regions where the IRWD products are present.
    The Drug Safety Physician reports to the VP Drug Safety and Pharmacovigilance.

    Responsibilities:

    • Medically review individual adverse event reports, both from clinical trials or post-marketing, for seriousness, expectedness and causality.
    • Identify and assess potential safety signals for Ironwood products, manage and track signals. Communicate to the Safety Review Committee as necessary. 
    • Collaborate with Business Partners, on the exchange of safety data, safety monitoring and safety profile, as laid out in Pharmacogivilance Agreements.
    • Represent Drug Safety on study teams and project teams. Review and approve safety sections of clinical trial protocols, analysis plans, study reports.
    • Write “Analysis of Similar Events” for SUSARs; review and approve Investigator Safety letters
    • Produce in depth safety analyses. 
    • Write Development Safety Update Reports (DSURs) and Post-Marketing Periodic Safety Updates (PSURs) as necessary. 
    • Provide medical safety input to Investigator's Brochures, IND and NDA submissions, Product Labels, MAA Annual Safety Reports and other regulatory documents and communications.
    • Closely collaborate with Safety Operations for seamless PV processes.
    • Collaborate with clinical trial directors for safety monitoring.

    Position Requirements:

    • Medically qualified with an MD or equivalent.
    • Medical expertise in internal medicine (board certification or eligibility and subspecialty training would be a plus, but is not required).
    • Minimum of 3 years industry experience and at least 2 years of clinical practice.
    • A good knowledge of GVP, particularly in relation to signal detection and evaluation and risk management, and of the regulatory requirements relating to pharmacovigilance in the US and internationally.
    • Be familiar with quantitative methods, experience in epidemiology is a plus
    • Working knowledge of MedDRA.

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  • 12/26/15--04:12: Extraction Technologist
  • Foundation Medicine is dedicated to helping bring personalized cancer medicine into routine clinical practice. Harnessing advanced technology, Foundation Medicine has developed clinical laboratory tests that broadly capture the most relevant tumor genomic and other molecular information and connect it with relevant scientific and medical knowledge to help oncologists determine the right treatment for each patient. This is a diverse, fast-paced, team oriented environment integrating laboratory science, cancer genetics and genomics, process data metrics and clinical data.

    Candidates should be highly motivated, confident with multi-tasking and attentive to details. This position will perform patient sample testing, equipment maintenance, solution and reagent preparation in addition to other tasks in a highly complex clinical diagnostic laboratory.

     

    Shift: Tuesday- Saturday, first shift

     

    • Perform complex testing according to established SOPs
    • Operate automated 8-span and 96-head liquid handling platforms for sample processing
    • Operate DNA/RNA extraction and quantification instruments
    • Demonstrate commitment to quality and continuous improvement
    • Complete projects under guidance of senior lab personnel
    • Perform daily, weekly, monthly and as needed equipment maintenance checks
    • Review and write SOPs as needed
    • Participate in reagent and assay quality control and validations as needed
    • Experience working in a regulated laboratory environment (CLIA/CAP)
    • Basic knowledge of laboratory safety protocols
    • Ability to learn new tasks in appropriate timeframes
    • Knowledge and experience working with DNA manipulation techniques and enzymatic reactions
    • Familiarity with high through-put platforms and common molecular laboratory equipment (pipettes, thermocyclers, liquid handlers, etc.)
    • Experience with ensuring and maintaining integrity and quality of the lab (sample processing, equipment, SOPs)
    • Proficiency utilizing Microsoft Office Suite

    Desired Skills and Experience:

    • Familiarity with Laboratory Information Management System (LIMS)
    • Well organized

     

    Education or Experience

    • Minimum BS in a Biological or Life Science
    • Minimum of 1 year of relevant lab experience in a CLIA/CAP lab
    • QSR compliant lab experience preferred but not required

     

     

    Apply Here

    PI92587467

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  • 12/26/15--04:16: Medical Technologist I
  • Foundation Medicine is dedicated to helping bring personalized cancer medicine into routine clinical practice. Harnessing advanced technology, Foundation Medicine has developed clinical laboratory tests that broadly captures the most relevant tumor genomic and other molecular information and connects it with relevant scientific and medical knowledge to help oncologists determine the right treatment for each patient. This is a diverse, fast-paced, team oriented environment integrating laboratory science, cancer genetics and genomics, process data metrics and clinical data.

     

    Candidates should be highly motivated, confident with multi-tasking and attentive to details. This position will perform patient sample testing, equipment maintenance, solution and reagent preparation in addition to other tasks in a highly complex clinical diagnostic laboratory.

     

    Shifts:

    Tuesday-Friday 3pm-11:30pm, Saturday 12pm-8:30pm Sunday 12pm-8:30pm, Monday-Thursday 3pm-11:30pm Tuesday-Saturday 7:30am-4pm Sunday-Thursday 7:30am-4pm

     

    • Perform highly complex testing according to established SOPs (NGS library prep, hybridization, and sequencing).
    • Operate automated 8-span and 96-head liquid handling platforms for sample processing.
    • Operate quantification, sizing, and NGS instruments.
    • Demonstrate commitment to quality and continuous improvement.
    • Complete projects under guidance of senior lab personnel.
    • Perform daily, weekly, monthly and as needed equipment maintenance checks.
    • Review and write SOPs as needed.
    • Participate in reagent and assay quality control and validations as needed.

    Job Requirements
    • Experience working in a regulated laboratory environment (CLIA/CAP)
    • Basic knowledge of laboratory safety protocols
    • Ability to learn new tasks in appropriate timeframes
    • Knowledge and experience working with DNA manipulation techniques, enzymatic reactions, and sequencing chemistry
    • Familiarity with high through-put platforms and common molecular laboratory equipment (pipettes, thermocyclers, liquid handlers, etc.)
    • Experience with ensuring and maintaining integrity and quality of the lab (sample processing, equipment, SOPs)
    • Proficiency utilizing Microsoft Office Suite
    • Familiarity with Laboratory Information Management System (LIMS)

    • Well organized
    • Minimum BS in a Biological or Life Science

    • 2+ years of relevant lab experience in a CLIA/CAP lab

    • QSR compliant lab experience preferred but not required

     

     

    Apply Here

    PI92587571  

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  • 12/26/15--04:20: Molecular Lab Assistant
  • Foundation Medicine is dedicated to helping bring personalized cancer medicine into routine clinical practice. Harnessing advanced technology, Foundation Medicine has developed clinical laboratory tests that broadly capture the most relevant tumor genomic and other molecular information and connects it with relevant scientific and medical knowledge to help oncologists determine the right treatment for each patient. This is a diverse, fast-paced, team oriented environment integrating laboratory science, cancer genetics and genomics, process data metrics and clinical data.

     

    Candidates should be highly motivated, confident with multi-tasking and attentive to details. This position will support laboratory technologists who perform patient sample testing. This position may include equipment maintenance and reagent preparation in addition to other tasks in a highly complex clinical diagnostic laboratory.

     

    FOUNDATION TITLE Assistant I, Laboratory Operations
    SHIFT MONDAY-FRIDAY 8AM-4:30PM

    • Stock and control inventory in the lab
    • Support reagent receipt activities as needed
    • File batch records
    • Prepare reagents
    • Perform routine maintenance lab maintenance including daily, weekly, monthly and as needed equipment maintenance.
    • Prepare labware for use by the technologists
    • Be a “sample manager” to help triage sample cancel requests and other inquiries to the appropriate lab person for response
    • Potential to help with de-bulking in accessioning.
    • Demonstrate commitment to quality and continuous improvement.
    • Manage lab coat requests
    • Follow instructions defined in SOPs

    Job Requirements
    • Well organized
    • Ability to learn new tasks in appropriate timeframes
    • Proficiency utilizing Microsoft Office Suite

    Desired Skills and Experience

    • Experience working in a regulated laboratory environment (CLIA/CAP)
    • Basic knowledge of laboratory safety protocols
    • Familiarity with Laboratory Information Management System (LIMS)

    Education or Experience

    • Minimum HS diploma or BS in a Biological or Life Science
    • Entry level position, relevant lab experience in a CLIA/CAP lab is preferred but not required

     

    Apply Here

    PI92587771

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  • 12/26/15--04:23: Computational Biologist
  • Job ID: 27461
    Date Posted: 12/22/2015
    Location: 450 Brookline Ave
    Job Family: Laboratory/Research
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow''s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.

    Computational Biologist, Single Cell Sequencing Program

    Single cell genomics and biology is at the forefront of human biological research today. For this reason, the Dana-Farber Cancer Institute is establishing a new Single Cell Sequencing Program.

    We are seeking an accomplished scientist with extensive experience in computational and statistical data analysis to innovate methods for single cell sequencing and to share these methods with collaborators. This individual will lead pioneering research in single cell genomics and single cell biology. This exceptional opportunity offers the chance to work at the forefront of the genomic and cellular understanding of cancer. This Computational Biologist will have the opportunity to innovate, to work closely with experimental colleagues and with biological and clinical collaborators.

    Key Responsibilities and Duties

    • Develop algorithms for the analysis of single cell DNA, RNA, RNA/DNA, and epigenome sequencing.
    • Evaluate algorithms developed by colleagues at other institutions and incorporate these algorithms into analysis where appropriate.
    • Work closely with experimental colleagues to evaluate and troubleshoot experimental methods.
    • Work closely with scientific colleagues to accomplish initial pioneer projects.
    • Share computational methods with DFCI colleagues by education and by the development of a shared service.
    • Other duties as assigned.

    Skills and Qualifications

    • Exceptionally deep computational and analytic abilities demonstrated by a top-tier Ph.D. in the life sciences with significant programming and algorithm development experience or a top-tier Ph.D. in math, physics, engineering, computer science, or a related field and familiarity with biological research problems.
    • Strong interest in and commitment to genomic research; previous experience in the field preferred but not required.
    • The successful candidate must be capable of understanding and translating high-level scientific goals into concrete computational approaches.
    • Excellent oral and written English communication skills are required.
    • Ability to interact with multidisciplinary colleagues including experimental biologists in a fast-paced environment.
    • Ability to work both independently and collaboratively with both experimental and computational biologists.

    Schedule

    40 hours per week, Monday - Friday

    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the ''Select'' column, and then click the ''Apply Now'' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.

    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

     

    Apply Here

    PI92587580  

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  • 12/26/15--04:27: Research Tech - Lead
  • Job ID: 27430
    Date Posted: 12/14/2015
    Location: Longwood Center
    Job Family: Technician/Technologist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    Principal duties and responsibilities:

    • Synthesis, purification and characterization of small molecules.
    • Conduct SAR study to optimize the compounds for activity, selectivity and drug properties.
    • Keep good record on all reaction conditions and compound information.
    • Discuss with collaborator on ongoing project and participate in initiating new project by looking for new lead compound.

    Requirements:

    • MS in organic chemistry or medicinal chemistry.
    • Must have college level organic and analytical chemistry knowledge.
    • Must have capability to use NMR, HPLC and LC-MS.
    • Must know how to use chemdraw, Scifinder and Pubmed
    • Must have knowledge of personal computer software (Microsoft Word, Excel and PowerPoint) in a business environment.
    • Must be detail oriented, self-motivating, and comfortable working in a team-oriented environment.
    • Good communication skills are required.

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases. 

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.



    Schedule

    Full time flexible


    The hours of this position will vary to meet deadlines in order to complete experiments and achieve project goals in a timely fashion.



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service.  Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression,  national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

      Apply Here
    PI92587600  

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  • 12/26/15--04:30: Research Technician
  • Job ID: 27020
    Date Posted: 09/03/2015
    Location: 450 Brookline Ave
    Job Family: Technician/Technologist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases. 

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.

    Job Description:

    To assist research in the laboratory and to maintain the laboratory ordering system, cell stocks, and general inventory. The employee will work in a good scientific environment and will be involved in setting up molecular techniques for genotyping samples from cancer patients as part of a major project that will investigate new therapeutic modalities for brain cancer. As part of a team effort, the employee is expected to develop and optimize methods to analyze large-scale tumor samples, including use of screening techniques for mutation analysis and gene dosage quantification. In addition, the employee will take part in sample processing and is expected to be involved in the interpretation of the assays.   The position will also involve participation in general laboratory duties such as generation of laboratory stock solutions, maintenance of cell- and bacterial-stocks, pouring plates, etc.   Participate in all laboratory maintenance duties as required.



    Schedule

     Full Time - 40 hours per week as needed



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service.  Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression,  national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

      Apply Here
    PI92597368

    0 0
  • 12/26/15--04:33: Research Tech - Senior
  • Job ID: 26985
    Date Posted: 09/16/2015
    Location: Longwood Center
    Job Family: Technician/Technologist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases. 

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.

    Research technician – biochemistry/cell biology

    Highly-motivated Senior Research Technician who will be responsible for providing technical support for ongoing research projects. Previous experience with basic cellular and molecular research techniques including tissue culture, western blotting and immunoprecipitation, extraction and analysis of DNA and RNA, PCR, RT-PCR and quantitative PCR as well as basic molecular cloning techniques are required. Experience with transfection, lentivirus infection, CRISPR, and other mammalian cell manipulations would be preferred.  Additionally, she/he will assist in ordering supplies and maintaining a stock of lab reagents.

    BS in biology or a related field and at least 5 years of professional laboratory experience. Good organizational and interpersonal skills and a working knowledge of data management, word processing, graphic software (Excel, MS Word, Graphpad/PRISM) is preferred.  Some work on nights and weekends may be required.



    Schedule

    Full Time Flexible. 

    The hours of this position will vary to meet deadlines in order to complete experiments and achieve project goals in a timely fashion.



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service.  Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression,  national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

     

    Apply Here

     

    PI92597482


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    Job ID: 25176
    Date Posted: 05/01/2015
    Location: 27 Dry Dock Ave, South Boston
    Job Family: Laboratory/Research
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

     Job Description - Dana-Farber Cancer institute (DFCI) is seeking a Preclinical Imaging Physicist to support the cancer research program at the Lurie Family Imaging Center (LFIC), the pre-clinical arm of the Center for Biomedical Imaging in Oncology (CBIO), one of the strategic Centers of the DFCI. CBIO is a centralized cancer imaging research enterprise that was established as a paradigm shift for translational cancer research through the integration of pre-clinical, clinical multidisciplinary expertise, and drug/probe development. 

    LFIC is a state-of-the-art preclinical imaging facility, spanning 14,000 sq ft and equipped with 7T MRI, microPET/SPECT/CT, ultrasound, optical, and microscopy imaging systems, and an image-guided irradiator.  Since its inception, the research conducted at the LFIC in longitudinal studies of tumor biology, therapeutic efficacies of novel agents, and pharmacodynamic efficacy, have contributed to top tier publications. The adjacent cyclotron facility, which opens early next year, will further expand the portfolio of novel imaging agents used for preclinical and translational research studies at LFIC.

    The Preclinical Imaging Physicist’s responsibilities will include the design, development, evaluation, participation and supervision of preclinical research studies involving PET, SPECT, CT imaging, and radiotherapy. The Preclinical Imaging Physicist will advise on and implement protocols for the microPET/SPECT/CT imaging and image-guided irradiation devices.The Preclinical Imaging Physicist will provide technical hardware and software support (in collaboration with the manufacturers/vendors), as part of a quality control program of the imaging and nuclear medicine hot-lab equipment, meet regulatory requirements, and oversee the technical and safety training for all personnel operating these devices. The duties of the Preclinical Imaging Physicist will require the ability to perform procedures associated with small animal imaging and willingness to become familiar with other imaging modalities such as MRI. It is also anticipated for the Preclinical Imaging Physicist to be familiar and proficient with kinetic modeling and texture analysis to implement imaging data radiomics.

    The Preclinical Imaging Physicist will build collaborations and will initiate and participate in multi-disciplinary research efforts.The successful candidate will work collaboratively with the animal/imaging technologists, administrative personnel, and scientists at the preclinical facilities, and with their counterparts in the disease centers’ clinics and research labs. They will work closely with other Centers and Departments at Dana-Farber Cancer Institute (DFCI) that are engaged in research on small animal modeling in cancer and in experimental therapeutics, and will partner with clinical affiliates to facilitate bidirectional translational cancer imaging science between the preclinical and clinical arms of the Center for Biomedical Imaging in Oncology (CBIO).The Preclinical Imaging Physicist will be expected to develop imaging research projects for presentation at national meetings and publication in peer-reviewed journals, including collaborative cross-modality studies and interdisciplinary studies.

    The Pre-Clinical Imaging Physicist will work closely with the LFIC Director and CBIO Leadership to execute the CBIO/LFIC vision and strategic direction of translational cancer research. The Preclinical Imaging Physicist will work with the executive leadership to make preclinical instrument acquisition decisions and manage capital and operational budgets, and revenue streams.

    Dana-Farber Cancer Institute supports a robust Scientist career track with multiple opportunities for advancement, leadership, and recognition. The successful candidate will be appointed to a level within the Scientist career track commensurate with his or her accomplishments and abilities. Promotion on this track will be based on achievement of goals.

     Minimum Qualifications

    • Advanced degree in physics, engineering, medical physics, or biomedical imaging
    • Two to three years experience in Nuclear Medicine and Radiological Imaging (specifically PET, SPECT, and CT) in a pre-clinical, clinical or research setting
    • Experience in operating microSPECT and microPET/CT scanners, and ability to process and analyze images
    • Record of scientific research, including peer-reviewed publications
    • Ability to establish independent research and secure external funding as a collaborating investigator

     Skills and Abilities Required

    • Excellent written and oral communication skills
    • Ability to communicate and collaborate with members of a multidisciplinary team
    • Ability to handle animals and perform procedures associated with small animal experimentation
    • Documented programming skills and competency in C, C++, Matlab, IDL, or other languages


    Schedule
    • Full-time, Mon-Fri 40 hrs per week; hours may vary and some weekends may be required based on project needs


    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service.  Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression,  national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

     

    Apply Here

     

    PI92597493

     

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    GENERAL SUMMARY OF POSITION: Under the direction of the Director or designee, the Project Coordinator I provides analysis and support for projects, administrative, and general operations. Responsible for independent action on multiple projects as assigned. Tasks vary according to the priorities of the department.

     

    MAJOR RESPONSIBILITIES:

    • Organize and plan work activities of the Department for review with appropriate senior staff
    • Implement and manage tasks in accordance with departmental objectives
    • Participate as a member of project teams
    • Assist senior staff with project development activities: compiling data, drafting reports, and assisting with special projects
    • Maintain project plans in Microsoft Project and produce related project reports
    • Compile and analyze data, and draft project reports for review by senior staff
    • Initiate and maintain contact with key personnel including staff, department heads and external parties
    • Update the Director or designee on project details and changes in a timely manner
    • Review pertinent correspondence, communications and other background materials on a daily basis to remain current on project and operation details
    • Draft routine correspondence, meeting minutes, management reports for the Director or designee and department staff
    • Prepare multi-media presentations and reports utilizing a variety of software applications including, but not limited to: Microsoft Word, PowerPoint, and Visio
    • Develop and maintain time schedules for department staff, project events and office activities
    • Maintain project files and support materials
    • Perform other duties as required.

    REQUIRED QUALIFICATIONS:

    • Bachelor's degree in business administration, a related field, or equivalent experience

    • 1 year of experience coordinating and planning projects

    • Ability to work in a team and meet performance deadlines in a dynamic environment
    • Excellent oral and written communication skills necessary to interact with clients and staff
    • Demonstrated experience in using computer-based tools including electronic mail, word processing, spreadsheet and database products.

     

     

    Apply Here

     

    PI92587700


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    Merrimack is a biopharmaceutical company discovering, developing and preparing to commercialize innovative medicines paired with companion diagnostics for the treatment of cancer. Merrimack seeks to gain a deeper understanding of underlying cancer biology through its systems biology-based approach and develop new insights, therapeutics and diagnostics to improve outcomes for cancer patients. Merrimack currently has six oncology therapeutics in clinical development and three additional candidates in late stage preclinical development. Merrimack's lead product candidate, MM-398, recently completed a Phase 3 trial in post-gemcitabine pancreatic cancer. Based on the results of this trial, Merrimack is currently preparing a New Drug Application for MM-398.

     

    The Associate Director will be working with a cross‑functional program team as the statistical lead, responsible for statistical activities across multiple studies, as well as providing strategic and technical support to functional area development. The ideal candidate is a good communicator, high-energy, self-motivated, and forward‑thinking. Experience working in oncology development is desirable, but not required.

     

    Job Responsibilities:

    • Provide leadership and guidance as the statistical expert on a cross‑functional program team
    • Apply statistical expertise to ensure optimal clinical trial designs, analysis methods and data displays
    • Be accountable for all statistical aspects of protocols and regulatory submissions
    • Represent Merrimack regarding statistical issues with external parties including regulatory agencies and corporate partners
    • Work collaboratively with internal and external (e.g. CRO) team members to coordinate the planning and execution of biostatistics deliverables
    • Work with data management personnel in the preparation of datasets that are of high quality and in usable format
    • Provide requirements to SAS Programmers to facilitate efficient and effective programming
    • Be responsible for quality assurance of data produced, the validity of the reported results and their statistical interpretation
    • Participate in the establishment of processes and standards for the generation and reporting of data
    • Contribute to the development of statistical approaches and support for biomarker analysis and translational research.

     

    Requirements: 

    • PhD in statistics or related discipline with at least 6 years of experience in the pharmaceutical or biotech industry preferred – will also consider MS with at least 8 years of experience

    • Demonstrated ability to effectively contribute to the statistical aspects of clinical protocol design, data interpretation, review and reporting of results for multiple studies and projects

    • Practical experience with application of advanced statistical methodologies to clinical trial design/analysis and with regulatory reporting/submissions

    • Experience managing outsourced biostatistical services

    • Proficiency with statistical software tools such as SAS, S-Plus, R, EAST

    • Familiarity with regulatory requirements and considerations (e.g. GCP, ICH, 21CFRpart11, CDISC)

    • Positive interpersonal work habits and communication skills

    • Ability to work independently and act with initiative to address issues

    • Ability to communicate statistical concepts in a clear and concise manner

    • Excellent verbal, writing, and presentation skills

    • Passion for fighting cancer

    If you are interested in a great opportunity with a fantastic company, please click the link to apply:

    https://hire.jobvite.com/j?cj=osRU0fwX&s=Mass_Biotech_Council


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