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Career postings for the Massachusetts Biotechnology Council

older | 1 | .... | 843 | 844 | (Page 845) | 846 | 847 | .... | 855 | newer

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    Primary Role
    Topics of research:
    * Cell engineering: utilize applied mammalian cell- and molecular biology, with special emphasis on genetic and metabolic engineering of industrially relevant mammalian host cell types, to modulate critical performance characteristics related to all aspects of recombinant protein expression, production cell health and robustness and product quality.
    * Genome editing: utilize advanced molecular genetic tools to develop hosts supporting streamlined generation of high producing manufacturing cell lines.
    * Develop, implement high throughput, small scale cell culture approaches and various selection and enrichment technologies to improve the efficiency and output of the stable manufacturing cell line development process
    * Develop, implement novel analytical (cell and harvest) approaches to identify clones producing biologics with the desired quality attributes
    * The developed methods and approaches as well as the resulting engineered cell lines will be directly used in ongoing preclinical stage programs and the candidate will be involved in the work of drug/process development teams

    Responsibilities
    100% Conduct research on topics listed under the "Primary duties" section

    Education & Experience Requirements
    Education: PhD in molecular biology, biochemistry, cell biology, biotechnology or similar discipline

    Scientific interest, training, thesis work:
    * protein production in mammalian cells including "difficult to express" molecules, modulating post-translational modification pathways including protein N glycosylation;
    * theoretical and practical experience with molecular genetics and genome editing methods;
    * demonstrated experience in generating engineered derivatives with desired phenotypes;
    * molecular, cellular and protein analytical/characterization methods, approaches;

    The expected duration of this position is a period of 24 months.

    Shire's Brave culture offers employees with diverse backgrounds the opportunity to enable those with life altering conditions to lead better lives. Shire is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by applicable law. US Applicants who require accommodation in the job application process may contact 484-595-8400.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=amVucy4zNTgxNi4zMTY3QHNoaXJlLmFwbGl0cmFrLmNvbQ


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    This position actively participates in and assists management in maintaining the quality and compliance of the Global PVRM organization through development and execution of global and departmental processes and standards, training, and compliance monitoring while fostering a culture of continuous process improvement and identifying opportunities to further enhance quality and compliance.

    Responsibilities:
    20%:
    Compliance Monitoring: Review global performance metrics for quality and submission timeliness. Investigate root cause and identify corrective and/or preventative actions. Develop/improve process, conduct trend analysis, and liaise internally across Shire and externally with alliance partners and vendors to identify root cause and CAPA. Identify areas for enhancement of the compliance monitoring process within PVRM. Train back-up personnel. Liaise with management relative to metrics.

    20%:
    Manage creation/revision of assigned procedural documents including cross-functional documents. Liaise with PVRM and cross-functional subject matter experts as necessary. Maintain department-specific documentation in support of the PV system in a document management system as directed.

    20%:
    Manage audit and inspection-related issues including inspection readiness activities, document procurement, responding to audit and inspection requests and reports as directed by the Head PV Compliance and Training. Manage internal tracking of PVRM commitments as directed by Head PV Compliance and Training.

    10%:
    Manage special projects as directed by Head of Compliance and Training and/or PVRM management.

    10%:
    Evaluate legislation related to pharmacovigilance system; work with PVRM SMEs to identify gaps with current process and articulate gaps to management as well as identify potential resolution to identified gaps. Ensure changes to legislation are reflected timely in PVRM process documents.

    10%:
    Manage the PVQST email box including alerting the Head PV Compliance and Training to any issues or issues that need to be addressed. Investigate issues and formulate answers to questions independently and seek advice when necessary.

    5%:
    Act as backup or primary if directed by the Head PVCT for the maintenance of the PSMF including providing metrics, QC, authoring sections or conducting training and investigation of any issues.

    5%:
    Manage curriculum for PVRM staff and identify any gaps or issues. Train back up and liaise with Head of PV Compliance and Training related to any issues that may develop. Identify areas for improvement. Maintain and conduct new hire on-boarding activities.

    Education & Experience Requirements:
    * Bachelors of Science degree preferred in medical or science-related field
    * 5+ years in pharmaceutical industry/compliance field
    * 3+ years' experience in metrics generation & review and procedural document creation or revision
    * Practical experience in the interpretation of PV regulations and implementation
    * Technical expertise with spreadsheets (Excel) and data review
    * Technical expertise with databases (Access, TrackWise, Argus, etc.)
    * Knowledge of Quality Management Systems, FDA/EU regulations and ICH guidelines for GXP or devices

    Other Job Requirements: Domestic or international travel may be required

    Shire's Brave culture offers employees with diverse backgrounds the opportunity to enable those with life altering conditions to lead better lives. Shire is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by applicable law. US Applicants who require accommodation in the job application process may contact 484-595-8400.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=c3N6Y3plc255LjMzNzYxLjMxNjdAc2hpcmUuYXBsaXRyYWsuY29t


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    Org Marketing Statement
    All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That's why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.

    Role Description
    The Clinical Operations Study Team Lead (Study Team Lead) delivers on Pfizer's commitment to develop new medicines by leading internal (Dev Ops) and/or external (Alliance Partner/Vendor/Contractors) operational resources to ensure that overall study timeline, cost and quality goals are met. The Study Team Lead is an expert on the operational delivery of clinical studies and brings that expertise to the design and conduct of clinical development at Pfizer. The
    Study Team Lead is accountable for the operational delivery of one or more clinical studies from study concept through reporting, submission and regulatory defense within one or more development projects. The Study Team Lead is responsible for operational oversight of all study activities and escalates issues when needed. The Study Team Lead provides joint leadership (in partnership with the Clinician) of the study team and ensures good team functioning.

    Responsibilities
    * Provides Study Team Leadership
    * Serves as co-lead (with Clinician) of study team and leads the Clinical Operations subteam
    * Ensures cross-functional connectivity among team members and supporting functional lines
    * Manages study team meetings and facilitates effective decision making
    * Fosters synergistic team health and engagement.
    * Supports Practical Clinical Study Design
    * Partners with Clinician and other team members and supporting functional lines to provide operational expertise and insight to inform protocol design.
    * Initiates and ensures a Protocol Operational Feasibility and Budget assessment is performed by seeking input from other lines within Development Operations and at the Alliance Partner/Vendor as needed.
    * Facilitates early engagement of Alliance Partners/Vendors when needed.
    * Provides Operational Oversight - Accountable for the operational success of the study.
    * Serves as primary Development Operations point of contact for the study. Engages early within project team to ensure effective up-front planning
    * Develops accurate study plans (timelines, budget) in concert with Alliance
    * Partner/Outsourcing Provider and utilizing resources from Dev Ops Lines and aligning with RU/BU business needs.
    * Provides critical assessment of AP and 3rd party vendor proposals. Pressure tests planning and resourcing assumptions to ensure success.
    * Oversees Site Feasibility and Site Selection Process in partnership with Clinical Trial
    * Execution Center of Excellence (Named COL, Global Site Start Up Unit) and Alliance
    * Partner/Vendor
    * Maintains collaborative working relationship with AP/CRO to provide appropriate level of AP/vendor oversight to ensure study success. Assists in issue resolution and escalation when needed.
    * Oversee and ensure appropriate and quality interactions between the site/investigators and CRO/Vendor related to the conduct of a clinical study.
    * Works proactively with AP/CRO and Pfizer internal functions to ensure timely delivery of data.
    * Leads Quality/Risk Management Activities - Proactively identifies risks to delivery or quality and ensures that appropriate risk mitigation plans are in place.
    * Oversees the study risk planning process (e.g. IQMP)
    * Communicates opportunities and risks to the RU/BU and Dev Ops project leadership. Ensures cross functional buy-in to risk mitigation plans.
    * Ensures compliance with all applicable SOPs and Quality Standards
    * Raises quality issues when required.
    * Coordinates and oversees inspection readiness activities including maintenance of study documentation.
    * Provides Cross Pfizer Coordination - Provides guidance on availability of expertise on Pfizer processes and systems with access to Pfizer subject matter experts to support AP/CRO tasks and issue resolution.
    * Provides Financial Oversight -Forecasts and manages high level clinical trial budget and supports invoicing approvals as needed and dependent on current process.

    Qualifications
    Education and Experience:
    * Experience in operationalizing clinical trials in Rare Disease required (minimum of 3 years of recent experience)
    * Recent experience working with Rare Disease KOLs at academic centers
    * Prior Pfizer experience (preferred)
    * B.A./B.S. or equivalent required; MS or higher degree, preferred
    * 10-15 years of Clinical Development experience
    * At least 7 years of direct project and/or study management experience required
    * Experience managing CRO staff to deliver clinical studies

    Technical Skills:
    * Thorough understanding of good clinical practices (GCP)
    * Thorough understanding of key operational elements of clinical research (e.g., site selection, monitoring, data acquisition and cleaning, reporting, etc.)
    * Develops and maintains relevant scientific knowledge within assigned program and or asset
    * Ability to participate and support sponsor regulatory interactions/inspections
    * Protocol design and operational feasibility assessment
    * Matrix team leadership
    * Vendor management
    * Strong knowledge in disease and technical areas pertaining to clinical studies
    * Effective leadership, project management, influencing, negotiating, problem solving, analytical, verbal, and written communications skills required to ensure executable study design and operational alignment
    * Strong networking & relationship building skills
    * Ability to identify, analyze, and manage risk

    EEO & Employment Eligibility
    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=c3VzYW4ubS5kaXBhZ2xpYS4zMDIwNS4zMTY3QHBmaXplci5hcGxpdHJhay5jb20


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  • 01/16/16--01:23: Associate Scientist
  • Org Marketing Statement
    A career at Pfizer offers opportunity, ownership and impact.

    All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

    Role Description
    * Responsible for performing all sample coordination activities to support regulated studies in the Andover site
    * Responsible, under the guidance of a bioanalytical principal investigator (BA PI), for the development of robust and reliable ligand binding and /or cell-based assays suitable for characterizing the disposition (PK) and Immunogenicity of biotherapeutics in various matrixes using a range of potential platforms and assay techniques.
    * Responsible for, under the guidance of a BA PI, timely delivery of drug concentration and immunogenicity data to PDM BioTX principle investigators.
    * Development and validation of assays to be governed per departmental SOP.
    * Accurate execution and documentation of bioanalytical methods in a regulatory compliant manner.
    * Ensure GLP/GCP compliance is maintained in laboratory during study support.

    Responsibilities
    * Perform all sample coordination activities to support regulated GLP/GCP studies
    * Bioanalysis for Biotherapeutic compounds, under the guidance of a BA PI, which includes,
    * Development and implementation of ligand binding assays (e.g. ELISA, ECL detection) to measure compound concentration, detection the presence of anti-drug antibody and neutralizing anti-product antibody activity in a regulated environment;
    * Design, development and implementation of appropriate cell-based assays.
    * Data analysis and interpretation and be able to draw conclusions regarding progress and results of work.
    * Gathering input from PDM colleagues, other departments, literature, and additional resources to assist in driving the project forward.

    Qualifications
    * BSc with at least 3+ years relevant GLP/GCP laboratory experience, with a focus on ligand binding assay development, cell-based assay experience; MSc with at least 1+ years relevant GLP/GCP laboratory experience with a focus on ligand binding assay development, cell-based assay experience.
    * Industry experience with a focus in biotherapeutics and a strong record of scientific achievement; excellent communication skills.
    * Skills in GLP/GCP complient analysis including following SOP and provision of quality regulatory documents.

    Technical Skill Requirements
    * Knowledge and hands-on experience developing ligand binding assays, utilizing various technology platforms.
    * Knowledge and hands on experience working under GLP/GCP regulations
    * Proven experience generating analytical data in a regulated environment
    * Proven analytical problem solving skill.
    * Proven ability to generate high quality data against challenging time lines
    * Ability to author technical documents like SOPs, data summary reports and analytical procedures.
    * Collaborative skills and effective partnering skills in a complex, multi-discipline organizational model.

    EEO & Employment Eligibility
    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=TWVnYW4uSGFycmlnYW4uMTA3MzMuMzE2N0BwZml6ZXIuYXBsaXRyYWsuY29t


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  • 01/16/16--01:28: Process/Project Engineer III
  • Org Marketing Statement
    A career at Pfizer offers opportunity, ownership and impact.

    All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

    Role Description
    Provide engineering and technical support related to the operation, maintenance, design, installation, startup/commissioning, testing, and qualification of production & Infrastructure equipment and systems within a biopharmaceutical manufacturing facility in Andover, Massachusetts. These systems may include production equipment such as bioreactors, fermentors, centrifuges, ultrafiltration skids, chromatography skids, Clean - In - Place (CIP) skids, and other support equipment such as WFI, Clean Steam, Process Gases, HVAC and Core Building Utility Systems. Particular focus for initial assignment to be capital project engineering for a new facility with evolution to facility operational support as described below. Specific accountability to ensure the quality of and compliance with Pfizer specifications during design, construction, commissioning and qualification during project life cycle phases.

    Responsibilities
    * Support the operation and lead troubleshooting of manufacturing equipment and control systems used in the manufacture of biopharmaceuticals
    * Support Tech Transfer activities for new products and product changeovers
    * Support reliability engineering for production and support equipment
    * Provide on the floor operational support as needed
    * Lead/Support the design and qualification of improvements, changes, or upgrades to this equipment as needed
    * Lead/Support the development of design and startup documents such as commissioning plans, User Requirement Specification (URS), Functional Requirement Specification (FRS), Configuration Specification (CS)
    * Lead/Support the development and execution of commissioning, validation and qualification documents and activities
    * Support the maintenance department as needed
    * Provide equipment maintenance history review
    * Support all investigations and audits as needed
    * Support process and component improvement projects as needed
    * Provide off-shift and on call support when necessary

    Qualifications
    * Candidate should have a BS/MS in Chemical or Mechanical Engineering or relevant discipline (ie. Biomechanical Engineering) + minimum of 4-6 years of industry experience
    * Candidate must be able to work across functional areas such as operations, maintenance, quality and regulatory.
    * Good communication skills, verbal and written, are required.
    * Knowledge of working with computers and associated applications such as MS Word, Excel, and PowerPoint are recommended.
    * Knowledge of database applications and AutoCAD are a preferred
    * Proficiency in the arena of Process, Utility and Building Engineering in a cGMP environment within a biopharmaceutical facility
    * Working knowledge of automated production systems with ability to manipulate and troubleshoot systems
    * Working knowledge of documents such as Piping & Instrumentation Diagrams (P&IDs), User Requirement Specifications (URS), Functional Requirement Specifications (FRS), Configuration Specifications (CS), and Qualification documents.

    NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS:
    * Minimal travel for equipment support and testing
    * Ability to work off shift (Nights and Weekends) as needed
    * Ability to work in a clean room environment

    EEO & Employment Eligibility
    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=SmltLlRhdm9saWVyaS41MzI3Mi4zMTY3QHBmaXplci5hcGxpdHJhay5jb20


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    Org Marketing Statement
    A career at Pfizer offers opportunity, ownership and impact.

    All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

    Role Description
    Provide engineering and technical support related to the operation, maintenance, design, installation, startup/commissioning, testing, and qualification of production & Infrastructure equipment and systems within a biopharmaceutical manufacturing facility in Andover, Massachusetts. These systems may include production equipment such as bioreactors, fermentors, centrifuges, ultrafiltration skids, chromatography skids, Clean - In - Place (CIP) skids, and other support equipment such as WFI, Clean Steam, Process Gases, HVAC and Core Building Utility Systems. Particular focus for initial assignment to be capital project engineering for a new facility with evolution to facility operational support as described below. Specific accountability to ensure the quality of and compliance with Pfizer specifications during design, construction, commissioning and qualification during project life cycle phases.

    Responsibilities
    * Support the operation and lead troubleshooting of manufacturing equipment and control systems used in the manufacture of biopharmaceuticals
    * Lead Tech Transfer activities for new products and product changeovers
    * Support reliability engineering for production and support equipment
    * Provide on the floor operational support as needed
    * Lead/Support the design and qualification of improvements, changes, or upgrades to this equipment as needed
    * Lead/Support the development of design and startup documents such as commissioning plans, User Requirement Specification (URS), Functional Requirement Specification (FRS), Configuration Specification (CS)
    * Lead/Support the development and execution of commissioning, validation and qualification documents and activities
    * Support the maintenance department as needed
    * Provide equipment maintenance history review
    * Support all investigations and audits as needed
    * Support process and component improvement projects as needed
    * Provide off-shift and on call support when necessary

    Qualifications
    * Candidate should have a BS/MS in Chemical or Mechanical Engineering or relevant discipline (ie. Biomechanical Engineering) + minimum of 10 years of industry experience
    * Candidate must be able to work across functional areas such as operations, maintenance, quality and regulatory.
    * Good communication skills, verbal and written, are required.
    * Knowledge of working with computers and associated applications such as MS Word, Excel, and PowerPoint are recommended.
    * Knowledge of database applications and AutoCAD are a preferred
    * Proficiency in the arena of Process Engineering in a cGMP environment within a biopharmaceutical facility
    * Working knowledge of automated production systems with ability to manipulate and troubleshoot systems
    * Ability to read and generate documents such as Piping & Instrumentation Diagrams (P&IDs), User Requirement Specifications (URS), Functional Requirement Specifications (FRS), Configuration Specifications (CS), and Qualification documents.

    NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
    * Minimal travel for equipment support and testing
    * Ability to work off shift (Nights and Weekends) as needed
    * Ability to work in a clean room environment

    EEO & Employment Eligibility
    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=SmltLlRhdm9saWVyaS4yODA4MS4zMTY3QHBmaXplci5hcGxpdHJhay5jb20


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    The Broad Institute of MIT and Harvard is the world’s leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.

    Founded in 2004 by Eric Lander and philanthropists Eli and Edythe L. Broad, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and beyond, with collaborations spanning more than a hundred private and public institutions in more than 40 countries worldwide. The Genomic Perturbation Platform at Broad is currently looking for a Research Associate to work as part of a team to execute high-throughput lentiviral CRISPR/Cas9 screens, including lentivirus production and infection of cultured cells.

    Responsibilities include:  
    - Cell culture and screening in a high-throughput facility.  
    - Manages lab resources with respect to equipment repair, ordering and organization.  
    - Executes high-throughput lentiviral RNAi screens in a high throughput and automation environment.  
    - Performs cell culture on up to 20 cell lines, and must be able to accurately monitor for contamination and cell line fidelity.  
    - Operates and maintains laboratory equipment to complete investigations.  
    - Prepares, orders, and maintains stocks of necessary reagents, solutions and supplies.  
    - Documents, compiles, and may analyze experimental data.
    - Reports data to supervisor in oral and written reports.  
    - Attends team meetings for experimental planning.  
    - Maintains and improves technical knowledge base.  
    - Other related tasks as required.
    - A bachelor's degree in biochemistry/biology or related field. Excellent critical thinking skills and attention to detail required.
    - Experience with mammalian cells and tissue culture required.
    - Must be able to use sound judgment to effectively solve problems and work independently.
    - Ability to handle a variety of tasks under biosafety level 2+ preferred.
    - Experience in a high-throughput research environment and interest in automation are pluses.

    *Off shift and weekend work is required in this roleThe Broad Institute will not offer visa sponsorship for this opportunity.
    EOE/Minorities/Females/Protected Veterans/Disabilities LI-POST

    To apply for this position, please CLICK HERE


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    Job ID: 27444
    Date Posted: 12/09/2015
    Location: Galleria
    Job Family: Clinical Research Coordinator
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.


    General Summary

    The Clinical Research Coordinator (CRC) works within the clinical research program and supports the research team in the overall conduct of clinical trials using Good Clinical Practice, under the auspices of the Principal Investigator. The CRC will be responsible for the primary data collection and management of patient clinical information as it pertains to participation in clinical trials. Ensures timely collection of protocol related samples including shipment to outside entities as required. Maintains regulatory binders and ensures study compliance with all state, federal, and IRB requirements. May be responsible for IRB protocol submissions (amendments, continuing reviews, and minimal risk protocols). This individual may also screen patients for protocol eligibility, obtain informed consent, and register study participants with the Quality Assurance Office for Clinical Trials (QACT).


    Duties & Responsibilities

    •Oversees the clinical trials start-up process from receipt of protocols through the Scientific Review Committee and IRB submissions, and site activation activities.
    •Responsible for data reporting and management, collection of source documents, use and development of case report forms, adverse events reporting, filing and archiving of study records, and resolution of data queries.
    •.Prepares and/or completes regulatory related reports and IRB submissions. Maintains and organizes study regulatory binders, and enters all required study data on an ongoing basis.
    •Ensures all study related samples are collected, properly prepared and shipped according to the protocol requirements and IATA/DOT regulations.
    •.Responsible for organizing and preparing for both internal and external auditing and study monitoring visits.
    •Coordination and management of clinical trials, including communication with Sponsors and regulatory authorities.
    •Close-out of clinical trials, including contributing to research articles, audit preparation, and communication with regulatory agencies and other disciplines involved.
    •Interacts with study participants as directed/required by the protocol and/or study team.
    •May be responsible for tissue sample work.



    Job Qualifications

    •Bachelor’s Degree required with 0-1 years of related experience preferred.
    •Requires close to moderate supervision.
    •Experience working in a medical or scientific research setting or comparable technology orientated business environment preferred.



    Knowledge, Skills & Abilities

    •Excellent organization and communications skills required.
    •Strong interpersonal skills – ability to effectively interact with all levels of staff and external contacts.
    •Must be detail oriented and have the ability to follow-through.
    •Ability to effectively manage time and prioritize workload.
    •Must practice discretion and adhere to hospital confidentiality guidelines at all times.
    •Must have computer skills including the use of Microsoft Office.



    Supervisory Responsibilities

    None



    Patient Contact

    May have contact with Adult and Pediatric patients of all ages and populations. May distribute protocol schedules, quality of life surveys or other study-related questionnaires, subject diaries, and/or conduct follow-up communication with patients.



    Schedule

    Full-time, Monday through Friday. 40 hours per week.

    Patient contact will be required.



    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.



    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.




    Apply Here

    PI92710520


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  • 01/16/16--02:39: R&D Associate I
  • GENERAL SUMMARY OF POSITION:

     

    The Research Associate I will be responsible for research and/or development of assays for support of antibody and biological drug development.

    MAJOR RESPONSIBILITIES:

    • Operates and maintains standard laboratory and department-specific equipment.
    • Prepares buffers, packs chromatography columns, carries out purification experiments, and makes detailed observations.
    • Performs analytical biochemistry assays and other laboratory testing as required.
    • Keeps timely and accurate documentation per cGMP, GLP, and MBL SOPs in notebooks and in electronic documents.
    • Coordinates with other group members to maintain and organize assay request and data entry on common projects.
    • Analyzes experimental data and provides accurate, concise and pertinent summaries and reports.
    • Provides support for protocol writing, project summaries and technical reports.
    • Prepares written and oral reports for presentation to the supervisor(s) and development group.
    • Maintains reagent and equipment inventories, orders supplies and cleans laboratory areas, hoods and common equipment.
    • Exercises technical discretion in the design, execution and interpretation of experiments that contribute to project strategies within defined parameters.
    • Perform additional job related duties as required.



    REQUIRED QUALIFICATIONS:

    • Requires a bachelor's degree in Chemistry, Biology, or related field with a minimum 0-2 years of relevant experience
    • Ability to follow instructions precisely, recognize deviations, and recommend corrective action within scope of training
    • Ability to troubleshoot within scope of training
    • Computer literate and proficient in MS Word, Excel and other relevant electronic systems
    • Strong critical thinking, time management and organizational skills. Demonstrated ability to manage and prioritize multiple projects and consistently meet deadlines
    • Possesses strong attention to detail, ability to maintain accurate records and excellent proofreading skills
    • Excellent written and verbal communication skills. Ability to communicate effectively with others
    • Ability to work effectively both independently and as a member of a team
    • Occasionally projects require flexibility in work schedule to meet business needs

    PREFERRED QUALIFICATION:

    • Working knowledge on protein purification and hands-on experience on chromatography workstations preferred

    Must be able to carry out the essential functions of this position, with reasonable accommodation if disabled

     

    SUPERVISION RECEIVED:

    Reports to Director of Product Discovery or designee.

     

    SUPERVISION EXERCISED:

    None

     

     

    ENVIRONMENTAL WORKING CONDITIONS:

    Job may require working with hazardous and infectious materials. Employees will receive appropriate training and be required to adhere to UMBL policies and procedures.



    Apply Here

    PI92720259


    0 0
  • 01/16/16--02:42: R&D Scientist I
  • GENERAL SUMMARY OF POSITION:

    R&D Scientist I is responsible for initiating and executing all preclinical scientific research and/or development strategies for monoclonal antibodies. Leads a team to the successful execution of departmental projects and achievement of departmental goals. Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products and problems. Plans and executes laboratory research.

    MAJOR RESPONSIBILITIES:

    • Develops methods for producing antigens required for immunizing HuMAb mice.
    • Screen hybridomas for reactivity with desired antigens.
    • Develops and implements in vitro assays to detect and measure biologic activities of all monoclonal antibodies.
    • Designs and implements strategies for selection of lead candidate antibodies and antibody conjugates.
    • Develops small animal models of disease. Aids in the completion of all in vitro and in vivo pre-clinical activity of lead candidate HuMAb antibodies.
    • Coordinates research activities with collaborators on HuMAb projects.
    • Performs organic chemistry techniques required for conjugating antibodies to protein and non-protein molecules.
    • Assists in compiling manuscripts, posters and oral presentations.
    • Keeps accurate records of experimental data to standards suitable to support publication, FDA submission, and patent filing. Ensures records of direct reports also meet this standard.
    • Analyzes experimental data and reports to senior management and research collaborators in a timely fashion.
    • Serves as a technical resource to the department and conducts moderately complex troubleshooting. Proposes creative problem solving approaches.
    • Takes an active role in the organizational aspects of the Product Discovery department such as ordering and equipment repair.
    • Hires, manages and trains staff. Plans and assigns duties to meet departmental and organizational objectives. Provides guidance and direction to staff; establishing expectations, defining roles, supporting career development and managing performance.
    • Performs additional job related duties as required.



    REQUIRED QUALIFICATIONS:

    • Requires a PhD in life science or related field and a minimum of 2 years of relevant experience or equivalent combination of education and work experience.
    • Ability to motivate personnel to work effectively and efficiently
    • Demonstrated capability to manage others, assign and schedule work, and conduct performance evaluations
    • Ability to maintain extensive working knowledge of current procedures within molecular and cell biology, biochemistry, and animal modeling.
    • Computer literate and proficient in MS Word, Excel and other relevant electronic systems
    • Excellent problem solving skills as well as time management and organizational skills. Demonstrated ability to manage and prioritize multiple projects and consistently meet deadlines
    • Possesses strong attention to detail, ability to maintain accurate records and excellent proofreading skills
    • Must have strong verbal and written communication skills. Ability to communicate effectively with others internally (up, down, and laterally) and externally to the organization
    • Ability to work flexible and at times, extended hours to meet business needs

    Must be able to carry out the essential functions of this position, with reasonable accommodation if disabled.

     

    SUPERVISION RECEIVED:

    Reports to Director of Product Discovery

     

    SUPERVISION EXERCISED

    May supervise lower level personnel

     

    ENVIRONMENTAL WORKING CONDITIONS:

    Job may require working with hazardous and infectious materials. Employees will receive appropriate training and be required to adhere to UMBL policies and procedures.

     



    Apply Here

    PI92720278


    0 0

    GENERAL SUMMARY OF POSITION:

    This research program is focused on the creation of improved genome editing technologies to facilitate both efficient and precise editing of vertebrate genomes.

     

    These improved nuclease technologies are being utilized in three areas of study: (1) developing reagents for precise gene correction/replacement that will be utilized for the gene therapy-based correction of monogenic diseases or the inactivation of integrated retroviral genomes; (2) engineering gene regulatory networks to deconvolute the signaling pathway that underpin cellular responses to external stimuli; and (3) improving reagents for the study of gene function in model organisms with a particular focus on zebrafish.

     

    These positions are open immediately for highly motivated candidates to develop and utilize CRISPR/Cas9 nucleases and effectors for investigating chromatin architecture and its influence on transcriptional activity in human cells.

     

     

     

    MAJOR RESPONSIBILITIES:

    • Conducts in-depth analysis of research experiments
    • Performs complex laboratory experiments
    • Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
    • Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
    • May modify protocols and be responsible for a single, independent research project
    • Assists in writing the text of scientific publications and grants. Reviews literature
    • Trains new laboratory personnel, students, and collaborators
    • Maintains laboratory supplies and equipment
    • Complies with all safety and infection control standards
    • Perform other duties as required



    REQUIRED QUALIFICATIONS:

    • Bachelor's degree in Biological Sciences, or equivalent experience
    • 1 year relevant research experience
    • Knowledge of Microsoft Office products
    • Strong ability to analyze complex visual data in a quantitative and objective manner
    • Judgment and action skills required to solve commonly encountered problems

    PREFERRED QUALIFICATIONS:

    • Experience with the construction of Illumina deep-sequencing libraries
    • Experience with mammalian cell culture
    • Experience with standard molecular biology techniques - cloning, PCR, qRT-PCR
    • Experience with CRISPR-Cas9 system a plus

     

     

     

     

     

    SUPERVISION RECEIVED:

    Under the direction of the Principal Investigator, or designee

     

    SUPERVISION EXERCISED:

    May functionally supervise Lab Technicians and Aides

     

    ENVIRONMENTAL WORKING CONDITIONS:

    Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.



    Apply Here

    PI92720572


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  • 01/17/16--09:00: Director of IT
  • PixarBio is searching for a qualified, highly motivated Director of Information Technology to lead the company's IT initiatives including network administration, desktop support and data center security. This position will report to the Chief Operating Officer.

    PixarBio’s primary mission is to research and develop FDA compliant novel biomaterials for sustained delivery of drugs, cells or biologics for treating various CNS disorders.

    Primary Responsibilities

    • Manage information systems and computer resources for the entire organization.
    • Oversee the organization's computer operations, systems and programming, desktop support, network administration, user services and data center.
    • Develop disaster recovery plans and manage back-up, archiving and security systems.
    • Interact with internal clients on all levels to help resolve IT-related issues and provide answers in a timely manner.
    • Manage user requirement definition and development, system configuration and testing, installation, implementation of ongoing support, system enhancements/upgrades and bug fixes.
    • Responsible for the introduction of new systems and hardware/software rollouts.
    • Develop and manage the department's budget.
    • Hire, train, and supervise information systems staff.
    • Build and maintain vendor relationships and purchase hardware and software products.
    • Ensure that company assets are tracked and maintained responsibly.

    Qualifications

    Requires BS in Computer Science or Business Administration and a minimum 5-8 years MIS management experience. Knowledge and experience of process modeling, reengineering and systems analysis is preferred.

    Required Skills 

    • Communicate professionally, clearly, concisely and consistently both verbally and in writing internally and externally.
    • Must be able to organize and prioritize work effectively to meet timelines with quality deliverables.

    Notes

    Authorization to work in the U.S. required.

    Compensation

    We offer a highly competitive salary commensurate with experience, options, medical, dental and vision coverage, 401K plan, flexible spending account, disability, and life insurance.


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    Compass Therapeutics is an antibody discovery and development company focused on comprehensively drugging the tumor-immune synapse with combinations of human monoclonal antibodies, multiclonals and engineered protein constructs.  Compass is industrializing antibody discovery and decentralizing biologic validation through a partnership-first mentality that leverages best-in-class technologies and top-tier academic laboratories around the world.  Novel scientific insights are validated and explored deeply inside our labs before Compass pursues the best proprietary combinations of therapeutics into human clinical trials.

    In 2015, Compass quietly closed a $120mm Series A financing to fund our ambitious plan to build a fully-integrated biopharmaceutical company from the ground up.  Our investors are among the most sophisticated venture capitalists in the industry who exemplify our philosophy of building long term economic value only by delivering therapeutics with meaningful efficacy beyond standard of care.  They include OrbiMed Advisors, F-Prime Capital (formerly Fidelity Biosciences), Borealis Ventures, Google Ventures and a handful of smaller VCs and passionate angel investors.

    Our Protein Engineering Group is seeking a hands-on Scientist or Senior Scientist at our Cambridge, MA site.
            
    Principal Responsibilities:

    • Contribute to the development and implementation of an optimized phage display platform for the discovery and engineering of antibodies
    • Establish tools for high throughput phage panning and antibody screening including the use of automation and next generation sequencing
    • Manage antibody discovery and optimization campaigns against multiple targets in the tumor immune synapse
    • Work closely with Protein Expression and Analytics groups to streamline processes for reformatting and screening phage output
    • Cure cancer. 

    Preferred Qualifications:

    • In-depth knowledge and hands-on experience with phage display and antibody selections
    • Experience with automation technologies for phage panning, expression, and/or screening
    • Experience with high-throughput antibody screening platforms such as IntelliCyt iQue, mirrorball, or comparable technologies
    • Ability to work in intense, fast paced, multinational work environment
    • Comfortable with balancing multiple project objectives simultaneously
    • Ability to lead actively and enthusiastically from the bench 

    Basic Qualifications:

    • Ph.D. in a relevant field with relevant scientific experience 

    Compass Therapeutics offers individually-tailored compensation packages which include competitive cash compensation, meaningful equity participation, comprehensive healthcare and adoption benefits, continuous career development, sabbatical programs, education reimbursement and many other benefits aligned with our philosophy of putting our team first.  Our labs are located at 450 Kendall Street in Cambridge, MA.


    0 0

    Responsibilities

    BASIC SUMMARY:

    Responsible for coordinating and managing the Corporate Assessment Program to minimize regulatory risk. Provide regulatory review of Quality Agreements (QAs), Master Service Agreements (MSAs), other technical contracts and regulatory filings.

    ESSENTIAL DUTIES AND RESPONSIBILITIES:

    •Manage the overall Corporate Assessment Program to ensure that all regulated operational units are in compliance with their respective regulations and applicable corporate policies.  

    •Develop annual assessment schedules, assign members to assessment teams, and participate in assessments as lead auditor or assign lead auditor when participation is not possible.  

    •Develop specific audit strategies for each assessment based on site complexity, compliance history and regulatory risk.  

    •Provide mentoring and guidance to assessment teams, evaluate performance of assessment team members and act as a liaison between assessment teams and site management.  

    •Develop an internal resource pool of compliance auditors.  

    •Ensure that all assessment reports are presented in a consistent format and are issued to site and senior management within established timeframes.  

    •Review site responses to ensure that all compliance issues are addressed appropriately, corrective measures are clearly defined and assigned to responsible individuals and that dates for completion are reasonable and achievable. Conduct follow-up assessments when necessary.  

    •Establish and manage corporate assessment program metrics for senior management review.  

    •Manage, in coordination with corporate legal and the various site managers, the review and edit/comment process for Quality Agreements (QAs), Master Service Agreements (MSAs) and other technical contracts between Charles River Laboratories and its clients.  

    •Perform regulatory review of QAs, MSAs and other contracts to determine scope of work, regulatory requirements and establish timeframe for completion.  

    •Develop and manage appropriate agreement/contract metrics for incorporation into an annual summary of these activities to be presented to senior management.  

    •Review all findings made by regulatory authorities auditing Charles River regulated sites. Review all site responses to regulatory findings to ensure that all site responses are timely, clear, concise and address the deficiencies described in the findings. Work with site QA and management to revise and edit responses as needed.  

    •Ensure that site responses to regulatory findings and related follow-up activities are consistent, systemic and effective in addressing the deficiencies found.  

    •Ensure that the routine regulatory filings of FDA and/or USDA regulatory documents such as Establishment Registrations, BLA Annual Reports, Establishment Licenses and Product Licenses are completed on time.

    •Perform all other related duties as assigned.

    Qualifications

    Education: Bachelor’s degree (B.A./B.S.) or equivalent in a science related discipline. Master’s degree (M.S./MBA) preferred.   •Experience: 5-7 years related experience in a pharmaceutical/ biotechnological/ medical Device related industry in the area of regulatory compliance.   •An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.   •Certification: None.   •Other: Must have excellent interpersonal and communication skills with the ability to influence and negotiate. Proficiency with desktop computer applications (word processing, spreadsheets, databases) and technical writing skills required. Detailed knowledge of FDA regulations required.

    Equal Employment Opportunity 

    Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet


    0 0

    Arietis is a Boston based start-up biotechnology company focused on the discovery and development of novel antibiotics. We are seeking a full-time employee to perform mouse models of infection to measure the effectiveness of novel antibiotics and to carry out additional microbiology/drug development experiments.

    Responsibilities will include performing daily health assessments of study animals, administering compounds, collecting and processing tissues, analyzing data and generating study reports.

    The ideal candidate will have:

    AALAS certification as Lab Animal Tech (LAT) and laboratory experience with mice. Those with 2-year, 4 year or Master’s degrees in Veterinary Sciences or a related field will also be considered.

    Basic laboratory skills and experience with microbiology.

    Strong preference will be given to candidates familiar with animal models of infectious disease, such as septicemia, thigh lesion, foreign body or topical infections.

    We encourage versatile candidates who will thrive in a fast paced startup environment to apply. Competitive salary and benefits based on qualifications.

    Send resume and cover letter to jobs@arietiscorp.com

     

     

     

     

     

     


    0 0

    Position Responsibilities:

    The Mgr/Sr Manager, Drug Product Manufacturing is an exciting opportunity to join Vertex’s growing Technical Operations team and facilitate rapid commercialization of new products while working with first-in-class, drug product development and commercial operations and external suppliers in an industry-leading Quality by Design (QbD) environment. Vertex Pharmaceuticals currently has three significant commercial products in addition to a very robust pipeline with multiple new molecules in various stages of clinical development. The successful candidate will have the opportunity to add significant value in two primary areas:

    • Product development - Partner with late-stage product development teams to ensure that process and product development activities result in commercially relevant processes with robust control strategies and design space features. The candidate will be expected to bring a real-world perspective to key design space studies as well as creativity and energy to these teams in order to promote positive and collaborative relationships with internal stakeholders and key external suppliers.

    • Commercial production support - Lead important cross-functional initiatives involving resources from across the Vertex organization to resolve complex commercial manufacturing issues, and to champion continuous process improvement activities, as needed. The successful candidate will have a solid understanding of related regulatory and business impacts in order to define and implement effective strategies for implementing post-approval changes. In order to succeed in this role, the candidate must be an excellent collaborator and a proven technical leader with experience in a cGMP pharmaceutical drug product manufacturing environment. The successful candidate will have a solid background in solid oral dosage form manufacturing and its related processes and unit operations, as well as technology transfer and scale-up.

    Position Qualifications:

    • Degree in an engineering discipline: BS/MS and 8+ years or PhD with 5+ years of relevant work experience 

    • Ability to travel up to approximately 20 – 30%

    Preferred Qualifications:

    • Proficiency with Quality by Design (QbD) concepts, statistical process control (SPC) and complex data analysis

    • Experience with biologic's and/or inhalation products is a definite plus

    • Experience with the operation of laboratory and pilot-scale manufacturing equipment Experience in technology transfer, scale-up, and late phase clinical development

    • Process Development experience in solid oral dosage forms and a sound understanding of the pharmaceutical development process

    • Must be a committed team player and collaborator

    • Demonstrates competency in the principles and practice of cGMPs and associated regulatory considerations in a pharmaceutical environment, including process, equipment, and facility validation experience

    • Strong knowledge of DOE concepts and practice as well as descriptive statistics ** Level will commensurate with experience


    0 0

    Associate Scientist I will join a Respiratory Science group committed to finding treatments for cystic fibrosis, COPD and other respiratory diseases.

    For details visit:

    http://www.cwsciences.com/Current-Openings/Associate-Scientist-I-Respiratory-Science

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


    0 0
  • 01/17/16--23:10: Quality Engineer (IVD)
  • Quality Engineer (IVD) will represent Quality Assurance during New Product Introduction/design transfer process.

    For details visit:

    http://www.cwsciences.com/Current-Openings/Quality-Engineer-IVD

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


    0 0
  • 01/17/16--23:12: QC Documentation Specialist
  • QC Documentation Specialist will perform quality control reviews of clinical documentation and review/edit documentation for technical accuracy.

    For details visit:

    http://www.cwsciences.com/Current-Openings/QC-Documentation-Specialist

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


    0 0

    The Controlled Substances Associate will participate in the tracking of and maintaining the controlled substances program, policies, and procedures under the guidance.

    For details visit: http://www.cwsciences.com/Current-Openings/Controlled-Substances-Associate

     

    Candidates must live local and be a US Citizen or Green Card Holder

    Email resume to: jobs@cwsciences.com

    Commonwealth Sciences is a professional recruiting firm specializing in Science, Engineering and Green Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.


    Commonwealth Sciences, Inc.
    http://www.cwsciences.com


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