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Career postings for the Massachusetts Biotechnology Council

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  • 01/22/16--00:56: Clinical Contracts Manager
    • Conducts contract negotiation, management, administration, and execution for Clinical Development Operations group within R&D Organization    
    • Global site budget responsibility for development, management, and finalization
    • Works independently to resolve complex contract issues within Clinical Trial Agreements, Consulting Agreements, Service Agreements, and others as needed. 

    Manages study contracting on a program level, and has frequent interaction with, and oversight of, outsourced contracting vendor.

    • Negotiates clinical trial contracts within established guidance.
    • Responsible for global site budget development and management; assures fair market valuation of procedures and fees
    • Administers templates for increasingly complex business/legal terms with minor supervision
    • Manages outsourced contracting function; ensures compliance with established processes
    • Independently negotiates agreements to completion
    • Liaise with Legal globally to ensure compliance with current legislation/guidance
    • Ensures compliance with internal timelines, metrics, and processes
    • Proactively identifies areas for process improvement; participates in cross functional initiatives
    • Applies an understanding of complex contract principles.
    • BA/BS and (7+ years direct industry contracting)
    • Excellent interpersonal, influencing and negotiation skills
    • Proven problem solving skills
    • Experience with industry budgeting tool (GrantPlan or GrantManager)
    • Strong analytical skills and detail orientation
    • Solid understanding of the clinical operations contracting processes

    Excellent written and verbal communication skills


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    Nominated by Fierce Biotech in 2014 as a “Fierce 15” company “that could change how physicians approach infectious disease,” Seres Therapeutics is well-positioned to become the first company to bring drugs to patients comprised of carefully selected commensal bacteria. Seres is a dynamic biotechnology company in Cambridge, MA with a passion for developing new drugs in areas of high unmet need. Seres is well-financed and has an advanced program for treatment of recurrent Clostridium difficile infection and a second clinical-stage program for Inflammatory Bowel Disease. As part of growing its pipeline and expanding the therapeutic impact of this novel type of treatment, Seres plans to enter the clinic with new product candidates in a range of therapeutic areas in 2016 and beyond.

     

    What's in it for you?

    In this role, you will build on Seres' unique screening technologies to create novel Ecobiotics for new indications. You will develop new assays and implement cutting edge technologies to expand Seres' capabilities to create and vet new combinations of commensal bacteria. We are creating live therapeutic products, and you will be at the center of that effort. You will be immersed in a learning organization, with a need to bring an open mind and an interest in rapidly developing and mastering the novel approaches required by new therapeutic space. You will develop important, enabling intellectual property and collaborate with functional teams including microbiology, bioinformatics and molecular biology.

     

    How do you know if you're the right fit?

    If you are a scientist who enjoys learning and problem solving in a fast-paced, team-oriented environment and who has experience with implementing high-throughput screening technologies, you'll fit in well at Seres. You will have previous experience performing screens for therapeutic candidates, including selecting high-throughput technologies and implementing them at the appropriate scale. You are comfortable with automation technologies, from robotics tools to liquid handlers and have developed medium- to high-throughput screens. You are fearless at adapting existing tools to meet new needs. You are a hands-on scientist who enjoys working in an intense and collaborative environment. You're motivated to succeed at developing new, innovative products. You will want to take the next steps in a new therapeutic area with a company that went from bench to bedside in record time.

     

    The other stuff

    This is typically a role best suited for PhD level candidates or exceptional non-PhD scientists with several years of experience. You will be comfortable working alone or in collaboration with Seres' teammates, as required. You will be an experienced microbiologist, biochemist or chemist with a deep knowledge of lead screening. You will be interested in building rapid screening platforms, and driven to bring new products to patients.

     


    Apply Here

     

    PI92742356


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    Do you consider yourself organized, meticulous, and enthusiastic? Our client is a dynamic biotechnology company in Cambridge, MA with a passion for developing new drugs in areas of high unmet need and they are looking for a Quality Assurance Specialist.  This position will assist the QA Team in quality system compliance and product quality.  You will also be maintaining systems and standards to ensure compliance with Gxp and International regulations.
    • Some additional components to the opportunity:
    • Support Quality, Manufacturing and Operations in a Documentation Systems capacity under minimal supervision.
    • Apply technical proficiency and attention to detail in troubleshooting and management of the Quality documentation and training systems.  
    • Coordinates implementation and maintenance of the controlled document management system companywide.
    • Proactively identifies opportunities for process improvement in the document control and training systems and works cross functionally to implement, as appropriate.
    • Reviews as document control all Policies, SOPs, Work Instructions, Forms, and Templates.
    • Facilitates  training documentation and processes.
    • Interacts with internal customers and functional groups at various management levels to provide customer service.
    • Assists in coordinating activities in support of audits and/or regulatory inspections, as required.
    • Participates as a representative of Quality on internal cross-functional project driven sub-teams, as required.
    • Assists all departments in the implementation, training and maintenance of the controlled document management system.
    • Manages the full life cycle of SOPs, Work Instructions, Attachments, and Templates within the controlled document system.
    • Performs other duties as assigned.
    REQUIREMENTS
    • B.S. in a scientific or allied health field (or equivalent degree) and at least 3 years of relevant GMP Quality Documentation experience
    • Experience working with electronic Document Management Systems (eDMS) a plus.
    About StratAcuity
    Whether you are seeking a career change or simply interested to become part of our network, you will appreciate the ethics guiding each StratAcuity team member. We build lasting relationships with exceptional scientists and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a StratAcuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

    CHEMISTRY IS EVERYTHING™


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    The Senior Regulatory Manager will be responsible for the core functions of regulatory operations (publishing, submissions, documentation, etc) as well as the management of 2 other full time employees. Seeking a seasoned candidate (min 8 years) who has experience in global submissions (US/EU/Japan is highly desirable) as well as direct report managerial experience.

    This is a permanent/salaried opportunity. Qualified candidates must have a strong work history as well as the desire to be a full time employee of this company.  

     

    Perks!

    • Under new executive leadership
    • Amazing Company Culture
    • Paid parking
    • Full Range of Benefits (Health, Vision, Dental)
    • 401k

     


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  • 01/22/16--01:33: Clinical Trial Manager
  •  

    Seeking a Contract Clinical Trial Manager (min 12 month with opportunity to renew) for one of Aerotek's top clients!

     

    The Sr. CTM will be responsible for:

    • Project and CRO Vendor Management
    • Working on Global Phase III projects
    • Execute development operation plans
    • Collaboration with internal and external stakeholders

     

    Please apply for more details!


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    In the Next-Generation Sequencing (NGS) workflow, the Senior Scientist, Sample Preparation, is responsible for the development of an automated sample-preparation process upstream of the sequencer. The candidate’s responsibilities include assessment of existing sample-preparation process, setting up an automation platform, and adapting existing protocols to the automation platform according to project requirements.

    The Senior Scientist will directly report to the Director of System Integration. The candidate will also be frequently reporting out intermediate work results to the matrix and line organization.

    • Build a strong core competency around sample preparation within the system integration group.
    • Define objectives and plan experiments required to meet project milestones.
    • Supervise work of research associates on a scientific-level across NGS workflow.
    • Establish quality control methods using either qPCR or BioAnalyzer
    • Analyze KPI’s (key performance indicators) and TPM’s (technical performance measures) to drive continuous process improvement.
    • Design and verify robust sample tracking methods (chain of custody).
    • Collaborate with other R&D groups to meet project objectives, more specifically with NGS System Integration group in Hilden (Germany).
    • Deploy GDP (good development practices) methods and SOPs in accordance w/ QIAGEN standards, methodologies and guidelines.
    • Maintain project documentations in accordance with internal and external requirements.
    • Contribute to development of intellectual property. 

    REQUIREMENTS

    MS/PhD in Biochemistry / Molecular Biology
    • At least 5+ years of relevant industry experience (NGS and adjacent technologies)
    • Expertise in DNA extraction and purification from FFPE samples, PCR amplification, qPCR and BioAnalyzer
    • Mandatory experience in assay development for DNA analysis (preferably next generation sequencing)
    • Excellent understanding of the underlying sample preparation chemistries for NGS workflows
    • Preferably some experience with automated liquid handlers (e.g. QIAsymphony)
    • Very good troubleshooting and problem solving skills
    • Strong technical writing and presentation skills

    • Strong work ethic with emphasis on taking initiatives

    • Light travel required (up to 10%)

    We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.


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    ARIAD is a Cambridge, Massachusetts-based biotechnology company focused on cancer. We are a cohesive team of talented people from diverse backgrounds with a shared vision: We seek to transform the lives of patients with breakthrough cancer medicines. This is our purpose. This is our passion. This is our promise.

    Job Summary:
    Reporting to the Senior Vice President of Corporate Affairs, the Associate Director of Investor Relations will be responsible for developing and implementing a successful investor relations program for ARIAD and will be accountable for its day-to-day management.  The Associate Director will help lead ARIAD’s communications with all existing and potential shareholders and research analysts that cover the company. The Associate Director of Investor Relations will work closely with senior management to communicate the company’s strategic objectives to the investment community and provide feedback from investors regarding the perception of the company’s performance.

     

    Duties and Responsibilities:

    • Develop and maintain productive relationships and dialogue with research analysts, investors and other key stakeholders
    • Collaborate with the Senior Vice President, Corporate Affairs and other executives to develop superb external communication plans relating to material corporate announcements
    • Serve as a corporate spokesperson to institutional investors and analysts
    • Manage quarterly earnings calls including the writing of the earnings press release, conference call script and management Q&As
    • Develop presentations and coach and prepare spokespersons for investor meetings
    • Lead the execution of large projects in support of communications strategies, including Annual Reports, presentations and website content
    • Maintain Wall Street consensus model on the company and its products
    • Monitor investment research on the company and its industry peers, and communicate competitive intelligence and analysis to senior management
    • Direct the company’s participation in investment conferences
    • Accompany road show teams and participate in key corporate presentations and Q&A
    • Manage Investor Relations portion of the company website

     

    Qualifications:

    • Education: Bachelor of Arts or Bachelor of Science degree, Masters of Business Administration degree preferred
    • 7-10 years of experience in the biotech/pharmaceutical industry with a focus on investor relations or corporate communications
    • Knowledge of financial modeling, with strong quantitative and analytical skills
    • A proven track record of developing productive relationships with the investment community
    • Exceptional oral and written communications and presentation skills
    • Demonstrated experience in effectively collaborating with executives and senior leaders
    • A proactive, strategic approach to communications
    • A professional, outgoing personality with a high level of energy, a strong work ethic, resourcefulness and flexibility

     

    ARIAD Pharmaceuticals, Inc. provides equal employment and affirmative action opportunities to applicants and employees without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability.

    Submitting a resume online at a job site could cause valuable screening information to be missed.

    Click here to apply: http://ariad-openhire.silkroad.com/epostings/submit.cfm?fuseaction=app.dspjob&jobid=620&company_id=16419&jobboardid=306

    ARIAD is an equal opportunity employer. The Company's policy is to afford equal employment opportunities to qualified individuals without regard to race, color, religion, national origin, ancestry, citizenship, marital status, veteran status, physical or mental disability, sex, sexual orientation or age and to comply with applicable laws and regulations. All employment decisions will be consistent with the principle of equal employment opportunity.


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    KSQ Therapeutics, Inc. has an immediate opening for a Senior Scientist-Drug Discovery position in Cambridge, MA.  Founded by pre-eminent scientific leaders, KSQ Therapeutics, Inc. is a drug discovery company employing cutting-edge functional genomics technology to identify novel pathways and targets involved in oncology and immuno-oncology.  We are developing this platform to uncover novel drug targets, mechanisms for drug efficacy and resistance to identify transformative single agent and combination therapies to transform patient lives.  We are looking for driven individuals who want to contribute to our fast growing company as a member of the founding scientific team.  KSQ is backed by Flagship Ventures and Polaris Partners, two of the premier life science venture capital funds with over 30 years combined experience in launching and growing new biotechs.

    Position summary:

    KSQ Therapeutics, Inc. is seeking an exceptional and highly motivated scientist to carry out cell-based assay development for small molecule single agent and drug combination efforts.  This position requires in-depth oncology experience to elucidate the mechanisms of drug sensitivity & resistance needed to discover and develop biomarker assays to drive drug discovery programs.  This person will directly influence the company’s efforts to translate our unique platform discoveries into novel drug discovery programs.  As part of the founding team of scientists at KSQ, this individual will be joining a dynamic, enthusiastic, and highly interdisciplinary environment.

    Key Qualifications

    • Ph.D. with 2+ years of experience with oncology small molecule drug discovery in an industry setting.
    • Proven experience developing cell-based assays for use in oncology; non-standard assays (FACS, soft agar, epigenetic tools etc.) highly desired.
    • Experience with conducting single agent & combination drug testing and prosecuting diverse areas of biology (signaling, biochemistry, gene expression etc.) is preferred.
    • Working knowledge of genome engineering approaches is valuable but not required.
    • Ability to think critically and creatively as part of a fast-paced research team.
    • Adaptability, commitment to scientific excellence, and team player mentality is a must.

    Responsibilities

    • The successful candidate will work as part of an interdisciplinary team contributing to the design and execution of experiments that support our drug discovery activities and goals
    • Participate in various aspects of this new company from building out the capabilities to contributing to generating data in a fast and efficient manner

    Compensation

    A competitive overall compensation package including: competitive base salary, bonus potential and stock options.

    Contact Information

    To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Dr. Wade Hicks at KSQJobs@ksqtx.com.


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    KSQ Therapeutics, Inc. has an immediate opening for a Scientist / Senior Scientist - Target Discoveryposition in Cambridge, MA.  Founded by pre-eminent scientific leaders, KSQ Therapeutics, Inc. is a drug discovery company employing cutting-edge functional genomics technology to identify novel pathways and targets involved in oncology and immuno-oncology.  We are developing this platform to uncover novel drug targets, mechanisms for drug efficacy and resistance to identify transformative single agent and combination therapies to transform patient lives.  We are looking for driven individuals who want to contribute to our fast growing company as a member of the founding scientific team.  KSQ is backed by Flagship Ventures and Polaris Partners, two of the premier life science venture capital funds with over 30 years combined experience in launching and growing new biotechs.

    Position summary:

    KSQ Therapeutics, Inc. is seeking an exceptional and highly motivated scientistto conduct work on developing and deploying cutting-edge precision functional genomics tools.  As part of the founding team of scientists at KSQ, this individual will have key technology development responsibilities, joining a dynamic, enthusiastic, highly interdisciplinary, and collaborative team.

    Key Qualifications

    • Ph.D. with post-graduate experience in genome engineering, cell biology, molecular biology, or a related field.
    • Extensive experience in molecular, cell biology, and mammalian tissue culture required.
    • Experience with library-based screening techniques (CRISPR or shRNA) and CRISPR-Cas9 genome engineering is desired.
    • Experience with mammalian expression systems, synthetic biology, and next generation sequencing is highly valuable
    • Ability to think critically and creatively as part of a fast-paced research team.
    • Commitment to quality, attention to detail, and team player mentality is a must.

    Responsibilities

    • The successful candidate will work as part of an interdisciplinary team contributing to the design and execution of experiments that support our research activities and project goals
    • Participate in various aspects of this new company from building out the capabilities to contributing to generating data in a fast and efficient manner

    Compensation

    A competitive overall compensation package including: competitive base salary, bonus potential and stock options.

    Contact Information

    To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Dr. Wade Hicks at KSQJobs@ksqtx.com.


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  • 01/23/16--09:04: Senior Account Executive
  • Torch Communications is a specialized public relations agency serving advanced technology and healthcare companies. Our clients are diverse, including cutting edge startups, growth stage organizations, and longstanding industry leaders. But they all share one common element: the drive to make the world a better place through true scientific and technological innovation.

    Our team has deep experience at some of the world’s top public relations agencies, bringing that expertise to a more flexible, client-friendly, “high touch” boutique service model. Founders are directly involved with client management, helping all levels of the team rapidly advance their skills. And our entire team - from interns to the executive suite - weighs in on new client areas to explore, and new capabilities to enhance our service.

    Client mix: tech, biotech, finance, health IT, venture capital

     

    Each day will be different, but as a Senior Account Executive at Torch, you will:

    • Be directly responsible for maintaining client accounts and successfully executing on critical projects – albeit in a collaborative environment where dissenting viewpoints are welcome and nothing’s done that way “just because it’s always been.”

    • Research, write, and edit a wide range of communications materials, including: customized outreach lists, intelligence briefings, press releases and press kit materials, and individualized media pitches.

    • Maintain workflows and execute on key projects, such as media pitching, event planning, and messaging development.

    • Assist with communications strategy and development of creative programs to help our clients reach their primary audiences.

    • Identify and cultivate new fields to explore and new capabilities to enhance our service.

    • Develop personal expertise in areas of science and technology relevant to our clients, and spread that fluency within the PR team.

    • Assist junior staff with their professional development.

     

    If you like what we’re saying, here’s what we’re looking for:

    • 3-5 years of experience in a role that requires significant writing, persuasive communications, strategy development, and management of complex projects – PR agency experience is highly preferred

    • Exceptional communications skills

    • Flexibility to wear multiple hats and manage projects simultaneously in a fast-paced environment

    • Ability to quickly grasp technical concepts from a mainstream perspective, with strong critical thinking skills that enable those concepts to be discussed in creative, fresh ways

    • Knowledge of digital services and proficiency in social media platforms

    • A sense of adventure as we look to grow and expand our reach

     

    Brownie points for:

    • Passion or exposure to startup culture and innovation in Boston and beyond

    • Experience implementing social media campaigns, including experience with analytics

    • Knowledge of graphic design, integrated communications, and/or brand marketing

     

    Torch participates in the Federal E-Verify program to confirm employment eligibility. We are an Equal-Opportunity Employer with offices in San Francisco and Boston.

     

    To apply, please send a cover letter and resume to bostonjobs@torchcommunications.com. As a bonus, send along any previous work and/or examples of your social media mastery as well.

     


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    The Quantitative Systems Pharmacology (QSP) Lab in Pfizer's Cardiovascular and Metabolic Diseases (CVMET) Research Unit is responsible for developing insights to help advance CVMET clinical candidates and identifying and evaluating promising new therapeutic targets through physiologically-based modeling and simulation, and analysis and interpretation of preclinical and clinical data. We seek a highly motivated postdoctoral candidate to develop and analyze mechanistic, mathematical models of cardiomyocyte biophysics to enable the in silico testing of mechanistic hypotheses and improve the identification and evaluation of therapeutic targets for the treatment of heart failure (HF).

    The successful candidate will apply quantitative systems modeling and simulation methods to develop a validated mathematical model that couples cellular electrophysiology and ion transients to cellular metabolism, mitochondrial function, and contractile force generation in human cardiomyocytes. In addition to enabling in silico identification and assessment of HF drug targets, the successful candidate will pursue new avenues for scientific development in areas of QSP modeling, cellular biophysics, data analysis, and uncertainty quantification. The mechanistic insights gained from detailed analyses of the in silico model will generate physiological hypotheses that may be tested experimentally and/or in the clinic. The expectation is that the resulting findings will lead to improved confidence in rationale for the pursuit of novel agents for the treatment of heart failure.

    Responsibilities
    * Develop a validated model of key pathways underlying cardiomyocyte properties, including cellular electrophysiology, metabolism, and contractile force generation; develop and implement numerical methods for parameter estimation and model simulation
    * Generate testable hypotheses regarding the pathogenesis and treatment of heart failure at the level of the cardiomyocyte, based on detailed analyses of model and simulation results
    * Identify, obtain, and organize primary data sets for use in defining parameter values/ranges and for model calibration and validation; contribute to the design of in vitro and in vivo experiments to resolve key knowledge gaps in our understanding of the biology
    * Present novel results at Pfizer and externally at regional or national meetings
    * Publish model and simulation results in high-impact journals

    Qualifications
    * Recent Ph.D. (0-3 years) in Engineering, Applied Mathematics, Physics or related discipline with strong numerical components focusing on mathematical modeling and simulation. Training and/or experience in mechanistic modeling of biological or physiological systems is preferred.
    * Understanding of theory, principles, and statistical aspects of mathematical modeling and simulation, including parameter estimation techniques
    * In-depth understanding of ordinary differential equations (ODEs) and how these can be applied in the development of complex models of biological pathways and systems
    * In-depth, hands-on knowledge of modeling and simulation software (MATLAB, C/C++ preferred)
    * Keen interest in learning new areas of biology and building on a solid foundation of quantitative and computational skills
    * Self-directed with ability to work independently
    * Team player
    * Excellent communication and writing skills
    * Primary authorship on relevant publications in peer-reviewed scientific journals

    NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT

    REQUIREMENTS

    Office-based position with minimal travel

    EEO & Employment Eligibility
    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

    Please apply at: Application URL:http://www.aplitrak.com/?adid=SmlsbGlhbi5TY2FubG9uLjY3Nzc1LjMxNjdAcGZpemVyLmFwbGl0cmFrLmNvbQ


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    Role Description
    Pfizer's Cardiovascular and Metabolic (CVMET) Disease Research Unit is looking for a candidate for the position of senior research associate. The successful candidate will have a deep knowledge and interest in cellular biology and will be responsible for -in vitro' studies. (S)he will have knowledge on common -in vitro' techniques, including but not limited to cell culture maintenance, differentiation and analysis of cells. Tasks include molecular biology analyses, such as western blot, PCR, in vitro protein handling, immunoprecipitation, microscopy or cellular imaging, siRNA knockdown, transfection, and viral infection techniques. (S)he will also perform functional assays in cell culture, such as glucose uptake or oxygen consumption. Candidates with a lack of prior experience in cardiovascular and metabolic diseases will be considered provided they can demonstrate strong expertise in general cell and molecular biology or biochemistry. (S)he will be responsible for organizing, processing and reporting experimental data and will attend and participate in regular laboratory meetings and discussions. Knowledge on mass spectrometry techniques is preferable, but not required.

    Responsibilities
    Pfizer's Cardiovascular and Metabolic (CVMET) Disease Research Unit is focused on identifying targets and developing compounds for the treatment of cardiometabolic disease. We are seeking self-motivated individuals with excellent oral and written communication skills and a deep interest in biological sciences. The candidate should have a strong interest in cell and molecular biology, strong written and oral communication skills, and the ability to function well in a team environment. Activities will include:

    *The prosecution of in vitro studies exploring the actions of potential anti-diabetic therapies using cell culture or primary cells, on parameters of relevance to diabetes, from study design, preparation, execution, and endpoint measurements.
    *Ability to maintain and differentiate cell culture, perform western blot and immunoprecipitation analyses, RNA and DNA extraction, RT-PCR experiment, immunocytochemistry, immunohistochemistry and microscopy analyses, siRNA techniques, glucose uptake and output experiments.
    *Knowledge of proteomics techniques is preferred, but not mandatory.
    *Maintenance of laboratory notebook records and adherence to safety policies is strictly required.

    Qualifications
    Education Requirements:
    BA, BS or MS with laboratory experience in appropriate scientific areas relevant to this position

    A degree in the following is strongly preferred:
    *Physiology, Biochemistry, Molecular Biology, Pharmacology, Cell Biology, Biomedical Engineering, Chemical Biology, Quantitative Biology

    Successful candidates will have 4+ years research associate experience and demonstrated skills in the following:
    *Experience with cell culture and primary cells maintenance and differentiation. Knowledge on culture and maintenance of skeletal muscle cells and adipose cells is preferred, but not mandatory.
    *Demonstrated experience with laboratory techniques such as western blot and immunoprecipitation analyses, RNA and DNA extraction and purification and transcriptomics techniques, immonocitochemistry, immunohistochemistry and microcopy techniques, FACS techniques, siRNA and shRNA delivery, ELISA and MSD assays, quantitative PCR, in vitro viral delivery, glucose uptake and glucose production assays.
    *Ability to grasp complex procedures, and adapt appropriately.
    *Proven verbal and written communication skills, and the ability to work in a collaborative team environment.
    *A working knowledge of statistics as it applies to experimental design and be able to conduct data analysis using Microsoft Excel, GraphPad Prism, or equivalent software.
    *Ability to complete experiments and present results in individual and group settings, including experience using Microsoft PowerPoint or equivalent software for this purpose.
    *Knowledge on proteomic, phosphoproteomics and in vivo techniques is preferred, but not mandatory.

    PHYSICAL/MENTAL REQUIREMENTS:
    Lifting, sitting, bending, standing, walking.

    Please apply at: Application URL: http://www.aplitrak.com/?adid=TWVnYW4uSGFycmlnYW4uNzc0MjIuMzE2N0BwZml6ZXIuYXBsaXRyYWsuY29t


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  • 01/23/16--03:38: Research Technician
  • Job ID: 27567
    Date Posted: 01/19/2016
    Location: Smith Building
    Job Family: Technician/Technologist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    FLSA Status: Exempt


    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

    Overview

    Duties and Responsibilities:

    A team of translational researchers led by Rameen Beroukhim at the Dana-Farber Cancer Institute and Broad Institute seeks a research technicianto join in efforts to apply cutting-edge genomic technologies to determine optimal treatment strategies for patients with brain cancers, with a particular focus on childhood cancers. The aim of these efforts is to perform translational research to develop new therapies to improve outcomes of patients diagnosed with these tumors. The work will be highly translational and span efforts from acquiring patient sample to generating and analyzing high-throughput datasets from those samples. To that end, the individual will engage in experiments involving genomic DNA/RNA isolation from cancer tissue and preparation of samples for gene expression profiling and next generation sequencing. The individual will utilize molecular biology techniques that include cell culture methods, recombinant DNA and gene transfer technology, and other cell biology assays (Western blots, immunoprecipitation, flow cytometry etc.). There will be opportunities to learn and assist in computational methods of analysis. The individual will also assist in daily laboratory operations and organization.

    Required Education, Experience, and Skills:

    A minimum of a Bachelors Degree or equivalent is required, preferably in the Biological, Biochemical Sciences or Computational Sciences. Prior research experience in biochemistry, molecular biology, or genetics is preferred. Experience with tissue culture, DNA/RNA purification, PCR amplification, subcloning, retroviral transfection; or computational coding, data management, and statistical analysis is a plus. The ideal candidate will be passionate about scientific discovery, a team player and, enthusiastic about scientific discovery to help improve patient outcomes, and highly self-motivated. A minimum two-year commitment is required.

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.

    Schedule

    Full Time

    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.

    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.




    Apply Here

    PI92748269


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    Job ID: 27566
    Date Posted: 01/21/2016
    Location: Yawkey Center for Cancer Care
    Job Family: Clinic Admin Sup Specialist
    Full/Part Time: Full-Time
    Regular/Temporary: Regular
    FLSA Status: Nonexempt


    About Dana-Farber

    Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

    Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.



    Job Description: This position is responsible for all aspects of patient scheduling in accordance with department scheduling guidelines. Provides superior customer service to all patients, family members, physicians and staff at all times in accordance with the DFCI Customer Service Standards. Assigned to work with a clinical practitioner group consisting of physicians, physician's assistants, technical supervisors, technical staff, program nurses and nurse practitioners and other care providers, the individual in this position will play a critical role in facilitating all aspects of patient care.

    • Under the direction of the clinical practice support management team, provides appointment scheduling ranging in complexity from one physician appointment to multiple care provider appointments in accordance with department scheduling guidelines for new and/or existing patients.
    • Performs front desk check-in and check-out functions (may defer complicated scheduling to Clinical Administrative Support Specialists as needed).
    • Obtains detailed clinical information face-to-face, by telephone or electronically.
    • May provide basic information regarding the need for insurance referral(s).
    • Performs independent patient and outside provider call triaging and assists in directing patient flow.
    • Serves as a liaison between patient/family/provider.
    • Recognizes emergencies and appropriately responses using standard operating procedures and critical thinking skills..
    • May provide general administrative support and coordination for all aspects of patient care for both new and/or established patients, including filing, document preparation, data entry, telephone support, etc.
    • May be responsible for scheduling numerous complex research protocols, involving extensive interaction with those associated with in-house studies, grant-funded studies and industry-sponsored clinical trials.
    • Requires clinical, operational and regulatory knowledge of the standard of care or clinical trial protocol for the patient population coordinated.
    • Prepares open and close provider schedules and handles daily schedule changes.
    • Performs past-pending reconciliations.
    • Enters data into patient care related databases.
    • May be required to perform other duties as required by the clinical practice support team.



    Schedule

    7:30-4pm or 6:30-3:00 pm depending on department needs

    How to Apply

    Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen.

    DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers.

    Equal Employment Opportunity

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.




    Apply Here

    PI92748125


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    GENERAL SUMMARY OF POSITION:


    This is an exciting opportunity to be at the forefront of gene therapy and vector manufacturing process development. The R&D Scientist I will be responsible for designing and implementing cell culture process development activities, including but not limited to: growth and feed medium development, shake flask and small-scale bioreactor process development and optimization studies, cell culture process scale-up and technology transfer. The Scientist I provides technical guidance and leadership to process development staff.

     

    This position is located at Fall River, MA

    MAJOR RESPONSIBILITIES:

    • Develops, optimizes and characterizes cell culture process for the production of gene therapy vectors, MAbs and other biologics.
    • Designs, performs and analyzes small-scale cell culture experiments.
    • Develops new cell culture growth and feed media formulations.
    • Bioreactor process scale-up to 250 L.
    • Transfers processes to the cGMP plant and supports cGMP manufacturing at up to 250L scale.
    • Ensures that all work is properly documented and suitable for regulatory submission.
    • Drafts technical reports to support technology transfer, regulatory and intellectual property submissions.
    • Maintains substantial knowledge of state-of-the-art principles in cell culture technology.
    • May manage process development projects and supervise junior process development personnel.
    • Works on problems of moderate scope where analysis of situation or data requires a review of identifiable factors. Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solution. Normally receives general instructions on routine work, detailed instructions on new assignments.
    • Perform additional job related duties as required.



    REQUIRED QUALIFICATIONS:

    • Requires a PhD in a relevant scientific discipline such as Chemical Engineering, Biochemistry, Molecular Biology, or other relevant field and a minimum of 0-2 years of relevant experience in cell culture process development and characterization.
    • Demonstrates potential for technical proficiency, scientific creativity, collaboration with others, and independent thought. Solid knowledge on scientific principles and concepts.
    • Must be detailed orientated with the ability to maintain accurate records and excellent proofreading skills.
    • Must have excellent time management and organizational skills, to meet deadlines with minimal supervision.
    • Experience with typical cell culture equipment and procedures including bench-scale and pilot-scale bioreactors, cell counters, metabolite analyzers, etc.
    • Experience in micro- and molecular- biology techniques such as molecular cloning, flow cytometry based assays and recombinant cell line development is a plus.
    • Experience with insect cell/baculovirus system is a plus.
    • Willingness to work extended and, at times, unusual hours to meet business needs.

    Must be able to carry out the essential functions of this position, with reasonable accommodation if disabled

     

    SUPERVISION RECEIVED:

    Reports to Director of Process Development or designee

     

    SUPERVISION EXERCISED:

    May supervise research associates

     

    ENVIRONMENTAL WORKING CONDITIONS:

    • Job may require working with hazardous and infectious materials. Employees will receive appropriate training and be required to adhere to UMBL policies and procedures.
    • Job may require flexibility to work unusual hours during production processes.



    Apply Here

    PI92747650


    0 0
  • 01/23/16--03:46: Quality Control Analyst II
  • Acorda Therapeutics, Inc. is a world leading pharmaceutical company focused on developing therapies that improve lives of people with neurological disorders. Acorda has a manufacturing facility in Chelsea, MA. The lead product in this facility is for the treatment of Parkinson’s disease. This product is in phase III of development and could profoundly increase the ability for many Parkinson’s patients to live relatively normal lives.

    The Quality Control Analyst II is responsible for executing QC testing and related analytical activities supporting product development, release and stability. This individual conducts routine and non-routine chemical and physical analyses of raw materials, in-process materials and drug products according to standard operating procedures. The Quality Control Analyst II compiles data for documentation of test procedures that may include stability program testing and formulation studies, participates in the preparation of investigations, summaries and reports, and reviews data obtained for compliance to specifications and reports out-of-trend and/or out-of-specification results. The Quality Control Analyst revises and updates standard operating procedures as needed.

     *Essential Duties and Responsibilities include the following. Other duties may be assigned.

    • Operates analytical instrumentation (i.e. HPLC, GC, UV-vis, FTIR, laser diffraction, KF).
    • Statistically and critically analyzes data for trending and reporting into regulatory filings. 
    • Participates in Laboratory and/or Quality Investigations.
    • Monitors equipment and instrumentation used on a daily basis to ensure proper operation and calibration.
    • Participates in the construction and/or revision of SOPs. 
    • Assists in the writing and updating of analytical test procedures, protocol, log books and checklists. 
    • Responsible for identifying and alerting a supervisor of issues on instruments and/or test executions; makes initial recommendations for possible solutions and/or corrective actions. 

     

    Education and/or Experience:

    • Bachelor’s Degree in Physical or Chemical Sciences (life sciences) required.
    • Minimum of 2-5 years of experience in a cGMP regulated environment required.
    • Chromatography skills using Empower and/or ChemStation preferred
    • Ability to troubleshoot and repair analytical instrumentation such as HPLCs and UPLCs preferred.
    • Demonstrated ability to lead and/or author investigations to determine root causes of OOTs and/or OOSs according to cGMP standards required.

     Qualifications:

    • Extensive experience with executing QC test methods, generating associated data packages, auditing data packages generated by others, troubleshooting instrumentation, trending data and statistical analyses required.
    • Experience with analytical method development and validation preferred.
    • Familiarity with executing Standard Operating Procedures in a GMP setting required.
    • .Critical understanding of the importance of documentation and data traceability required.
    • Working knowledge of cGMP’s and their application to Quality Control required.
      • Experience with MS  Office Suite

     

     Please visit our website to learn more about Acorda and the QC II Analyst opportunity. 


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    GENERAL SUMMARY OF POSITION:

    Our current emphasis is on mechanisms of genetic interference pathways specified by CRISPR loci in pathogenic bacteria. We have employed biochemical, molecular biological, and genetic approaches to uncover the fundamental principles that govern these processes, with considerable success. Most notably, we demonstrated in 2008 that the molecular target of CRISPR interference is DNA rather than RNA, setting the stage for the recent explosion in CRISPR-based genome manipulation.

     

    Under the general direction of the Principal Investigator or designee, the Research Associate II performs a variety of complex research experiments and is responsible for overseeing and managing laboratory operations within the Department.

     

     

     

     

    MAJOR RESPONSIBILITIES:

    • Perform complex laboratory experiments and conduct in-depth analysis of research experiments
    • Write standard operating procedures, schedule work, analyze data, maintain accurate records, and write reports
    • Report the status of projects and observations to the Department Chair
    • Ensure departmental computer resources remain functional and provide on-site support to Investigators as requested
    • Design and execute protocols and experiments, modify protocols as needed, and may be responsible for own research project
    • Manage laboratory research staff
    • Responsible for overall laboratory organization including oversight of safety protocols and the maintenance of related records
    • May assist with budget and/or operational aspects of grant and contract proposals
    • Long-range planning for laboratory and departmental equipment maintenance and replacement. Assist in procurement of departmental equipment. Responsible for physical inventory of all equipment, and maintaining records of all equipment acquired, moved off-site, or discarded
    • Oversee and coordinate the use of centralized departmental facilities
    • Work with Facilities Engineering, Environmental Health and Safety, and Radiation Safety to ensure department facilities and laboratories are in compliance with federal, state and institutional regulations
    • Assist in writing the text of scientific publications and grants. Review literature
    • Oversee and assist in the training of new laboratory personnel, students, and collaborators
    • Comply with all safety and infection control standards
    • Perform other duties as required

    REQUIRED QUALIFICATIONS:

    • Bachelor's degree in the Biological Sciences, or equivalent experience
    • 5 years of relevant research experience
    • Knowledge of Microsoft Office products
    • Strong ability to analyze complex visual data in a quantitative and objective manner
    • Judgment and action skills required to solve commonly encountered problems

    PREFERRED QUALIFICATIONS:

    • Minimum 5 years experience in molecular biology, and tissue culture
    • Minimum 5 years experience, laboratory management
    Additional Information:

    SUPERVISION RECEIVED:

    Under the direction of the Principal Investigator, or designee

     

    SUPERVISION EXERCISED:

    Supervise aides, technicians, and associates

     

    ENVIRONMENTAL WORKING CONDITIONS:

    Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens



    Apply Here

    PI92755558


    0 0

    Acorda Therapeutics, Inc. is a world leading biotechnology company focused on developing therapies that improve lives of people with neurological disorders. Acorda has a manufacturing facility in Chelsea, MA. The lead product in the Chelsea facility is for the treatment of Parkinson’s disease. This product is in phase III of development and could profoundly increase the ability for many Parkinson’s patients to live relatively normal lives.

    The Quality Control Analyst IV is responsible for executing QC testing and related analytical activities supporting product development, release and stability. This individual conducts routine and non-routine chemical and physical analyses of raw materials, in-process materials and drug products according to standard operating procedures. The Quality Control Analyst IV compiles data for documentation of test procedures that may include stability program testing and formulation studies, participates in the preparation of investigations, summaries and reports, and reviews data obtained for compliance to specifications and reports out-of-trend and/or out-of-specification results. The Quality Control Analyst IV revises and updates standard operating procedures as needed.

     *Essential Duties and Responsibilities include the following. Other duties may be assigned.

    • Operates analytical instrumentation (i.e. HPLC, GC, UV-vis, FTIR, laser diffraction).
    • Statistically and critically analyzes data for trending and reporting into regulatory filings. 
    • Participates in Laboratory and/or Quality Investigations.
    • Monitors equipment and instrumentation used on a daily basis to ensure proper operation and calibration.
    • Participates in the construction and/or revision of SOPs. 
    • Assists in the writing and updating of analytical test procedures, protocol, log books and checklists. 
    • Responsible for identifying, alerting and proposing solutions to issues on instruments and/or test executions; leads and implements recommended solutions and/or corrective actions.
    • Independently organizes work flows to accomplish objectives, provides guidance and support to colleagues as needed, promotes new policies and programs tactfully and authentically, and may author/document performance reviews and/or evaluations. 

     

    Education and/or Experience:

    • Bachelor’s Degree in Physical or Chemical Sciences (life sciences) required.
    • Minimum of 5-8 years of experience in a cGMP regulated environment required.
    • Experience in MDI/DPI analytical test methods (i.e. Andersen Cascade Impactor and Emitted Dose techniques) preferred.
    • Demonstrated ability to lead projects and/or teams independently
    • Ability to author investigations to determine root causes of OOTs and/or OOSs according to cGMP standards required.
    • Ability to troubleshoot and repair analytical instrumentation such as HPLCs  preferred.
    • Experience with analytical method development and validation preferred

     Supervisory Responsibilities:  This position may supervise a small group of QC Analysts

     

    Qualifications:

    • Extensive experience with executing QC test methods, generating associated data packages, auditing data packages generated by others, troubleshooting instrumentation, trending data and statistical analyses required.
    • Familiarity with executing Standard Operating Procedures in a GMP setting required.
    • Chromatography skills using Empower and/or ChemStation
    • Critical understanding of the importance of documentation and data traceability required.
    • Working knowledge of cGMP’s and their application to Quality Control required.

     

    Please visit our website www.acorda.com to learn more about Acorda Therapeutics, Inc.


    0 0

    Scientist, Protein Characterization

    About Acceleron:

    Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutic candidates that regulate cellular growth and repair.  The company is a leader in understanding the biology of the Transforming Growth Factor-Beta (TGF-β) protein superfamily, a large and diverse group of molecules that are key regulators in the growth and repair of tissues throughout the human body, and in targeting these pathways to develop important new medicines. Acceleron has built a highly productive R&D platform that has generated innovative clinical and preclinical protein therapeutic candidates with novel mechanisms of action.  These protein therapeutic candidates have the potential to significantly improve clinical outcomes for patients with cancer and rare diseases. 

    Position overview:

    We are seeking an experienced and highly motivated Scientist with expertise in analytical characterization of proteins and antibodies to join our R&D team. This hire will play a key role in the development and execution of new analytical methods to support our growing drug pipeline. The candidate will be responsible for  characterization of various discovery molecules with a wide variety of analytical techniques including LC-MS, complex glycan analysis (N-linked, O-linked), HPLC and capillary electrophoresis to support discovery at different stages. This hire may be involved in assessment of drug candidate stability and pre-formulation. We are looking for a candidate who is able to design new approaches to attack complicated problems uncounted during biologics process development and potentially provide directions for process improvement to discovery scientists. Candidates with extensive experience in characterization of mAbs as well as bispecific antibodies are especially encouraged to apply. The title will be determined based on the experience.

    Basic Qualifications:

    • Ph.D. Chemistry/Biochemistry or related discipline with 2+ year experience in biotech industry/post-doc training in characterization of biologics or MS with 5-8 year experience
    • Excellent knowledge of analytical techniques of protein characterization
    • Solid understanding of protein structure
    • Extensive knowledge in state-of-the-art analytical technologies and instrumentation
    • Extensive hands-on experience with development of HPLC (IEX, SEC, etc.), LC-MS (peptide mapping and N-linked glycan), and CE (cIEF and CE-SDS) methodologies
    • Prior experience with complex glycosylation characterization and analysis is required
    • Hands-on experience with DLS, DSC, CD, AUC is essential
    • Experience with Biacore and/or Octet is highly desirable
    • Ability to plan, schedule and carry out work for multiple projects
    • Demonstrated technical expertise and creative problem-solving ability
    • Ability to work independently, with minimal supervision, and to manage multiple projects at one time
    • Excellent oral and written communication skills
    • Enthusiastic with a high-level of integrity and attention to detail

    *Recruiters - please do not send unsolicited resumes to this posting.

    FOR IMMEDIATE CONSIDERATION PLEASE VISIT OUR WEBSITE AT:

    www.acceleronpharma.com


    0 0
  • 01/24/16--09:13: Analytical Chemist
  • Leading society’s mandate for non-opiate and non-addictive pain treatments, PixarBio is searching for a qualified, highly motivated individual to serve as Analytical Chemist.

    PixarBio’s NeuroRelease is a novel micro-particle drug delivery platform comprised of US FDA approved drugs and biomaterials.  PixarBio is a Project Management focused organization, and we seek an Analytical chemist with project management mindset. 

    Co-founded by Frank Reynolds and MIT’s Robert S Langer PixarBio’s leadership is unmatched in Medical R&D success.  The Analytical Chemist will report to Director, Analytical Chemistry. 

    PixarBio’s CEO, Frank Reynolds, won 2013 Best Company to work for Boston Business Journal, and 2013 CFO of the Year runner-up Boston Business Journal and has been hiring and developing people for almost 40 years.

    Mr. Reynolds is also the lead inventor of significant neurological advancements, InVivo Therapeutics’ NeuroScaffold and PixarBio’s NeuroRelease.  Frank is a neurological R&D expert and he has filed a wide range of patents covering NeuroScaffolds, NeuroRelease, and neuro-biomaterials cGMP manufacturing. 

    The CEO has been creating, capturing, and monetizing value while leading businesses since 1980.  He is a true partner in your success.  You’ll rarely if ever work for a Pharma CEO who owns more than 60% of the company but Frank Reynolds is THE majority owner of PixarBio and we avoid VC issues that distract projects from their critical paths to success.

    PixarBio's primary mission is to research and develop novel biomaterials for sustained delivery of drugs, cells or biologics for treating various CNS disorders.  A medical history making leadership team with almost 70 products approved for US FDA human study in spinal cord injury, cancer, regenerative tissues, and a wide variety of drug delivery systems, we’ve advanced NeuroRelease’s 14 day post-op pain treatment to be ready for the clinic.

    PixarBio’s intends to replace opiates and other addictive pain treatments in early 2018.  Our primary mission is to research and develop sustained drug, cell, and biologic delivery systems, for acute/chronic pain, epilepsy, spinal cord injury, and Parkinson’s disease.

    We rely on our R&D model to create our innovative engine, providing a creative work environment.  We have sought replacements for morphine for centuries so PixarBio combines a once in a life-time experience to join neuroscience’s most productive team. 

    Robert Langer, ScD, Co-Founder of PixarBio is #1 in the history of US Life science patents, trailing only Thomas Edison for #1 in US history of patents.  Frank Reynolds, CEO and Co-founder of PixarBio invented the NeuroScaffold, won top 50 scientist in Ireland history, and he is co-inventor on 50+ pending and or issued biomaterials/life science patents.

    About the Job

    PixarBio is searching for a qualified, highly motivated analytical chemist to join our analytical team to carry out daily works on characterization of biomaterials for drug delivery. 

    Our primary mission is to research and develop FDA compliant novel biomaterials for sustained delivery of drugs, cells or biologics for treating various CNS disorders. 

    Primary Responsibilities

    Conduct routine analyses and data process of biomaterials using HPLC/UPLC, GC, TGA, DSC, and other analytical instruments

    • Assist in HPLC/UPLC, GPC, GC, and other analytical methods Development and validations
    • Help maintain and troubleshoot analytical instruments
    • Communicate results and observations to the analytical, engineering, and process development teams
    • Think creatively, problem solve, and develop innovative solutions based on sound scientific analysis.
    • Other duties as required

    Qualifications

    MS in Chemistry or Analytical Chemistry 2-3 years of hands-on experience with analytical measurements and instrumental analysis in the pharmaceutical or biotechnology industry,

    or

    BS in Chemistry or Analytical Chemistry 3-5 years of hands-on experience with analytical measurements and instrumental analysis in the pharmaceutical or biotechnology industry.

    Required Skills 

    • Instrumental analysis, including, HPLC/UPLC, GPC, SEC, GC, FT-IR, ion-exchange chromatography
    • Experience working in a cGMP/GLP environment
    • Experience with biomaterials and drug delivery is a plus.
    • Ability to execute controlled experiments with a strong attention to detail is essential.
    • Driven self-starter with capability to work independently as well as on interdisciplinary teams with biomedical engineers, chemical engineers, analytical chemists, materials scientists, quality specialists, biologists, etc.
    • Comfortable working on high risk technologies in a fast paced, high pressure start-up environment.
    • Proficient computer skills including MS Office and statistical analysis software.
    • Proficient oral and written communication skills.

    Notes

    Authorization to work in the U.S. required. 

    Compensation

    We offer a highly competitive salary commensurate with experience, options, medical, dental and vision coverage, 401K plan, flexible spending account, disability, and life insurance.


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